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<p>Contributors ix</p> <p>Preface xi</p> <p>Chapter 1 Defining the equine genome: The nuclear genome and the mitochondrial genome 1<br /><i>Bhanu P. Chowdhary</i></p> <p>Chapter 2 Genetic linkage maps 11<br /><i>June Swinburne and Gabriella Lindgren</i></p> <p>Chapter 3 Physical and comparative maps 49<br /><i>Terje Raudsepp and Bhanu P. Chowdhary</i></p> <p>Chapter 4 The Y-chromosome 73<br /><i>Terje Raudsepp, Nandina Paria, and Bhanu P. Chowdhary</i></p> <p>Chapter 5 Unexpected structural features of the equine major histocompatibility complex 93<br /><i>Loren C. Skow and Candice L. Brinkmeyer-Langford</i></p> <p>Chapter 6 Assembly and analysis of the equine genome sequence 103<br /><i>Claire M. Wade</i></p> <p>Chapter 7 Genomic tools and resources: Development and applications of an equine SNP genotyping array 113<br /><i>Molly McCue and Jim Mickelson</i></p> <p>Chapter 8 Functional genomics 125<br /><i>Stephen J. Coleman, Michael J. Mienaltowski, and James N. MacLeod</i></p> <p>Chapter 9 Coat color genomics 143<br /><i>Samantha A. Brooks and Rebecca R. Bellone</i></p> <p>Chapter 10 Genomics of skin disorders 155<br /><i>Amy E. Young, Stephen D. White, and Danika L. Bannasvch</i></p> <p>Chapter 11 Genomics of muscle disorders 171<br /><i>James R. Mickelson, Stephanie J. Valberg, Carrie J. Finno, and Molly E. McCue</i></p> <p>Chapter 12 Genomics of skeletal disorders 187<br /><i>Ottmar Distl</i></p> <p>Chapter 13 Genomics of reproduction and fertility 199<br /><i>Terje Raudsepp, Pranab J. Das and Bhanu P. Chowdhary</i></p> <p>Chapter 14 Genetics of equine neurologic disease 217<br /><i>Carrie J. Finno and Monica Aleman</i></p> <p>Chapter 15 Molecular genetic testing and karyotyping in the horse 241<br /><i>M. C. T. Penedo and Terje Raudsepp</i></p> <p>Chapter 16 Genomics of laminitis 255<br /><i>Jim K. Belknap</i></p> <p>Chapter 17 Genomics of performance 265<br /><i>Emmeline W. Hill, Lisa M. Katz, and David E. MacHugh</i></p> <p>Chapter 18 Genomics of the circadian clock 285<br /><i>Barbara A. Murphy</i></p> <p>Chapter 19 Mitochondrial genome: Clues about the evolution of extant equids and genomic diversity of horse breeds 311<br /><i>Cynthia C. Steiner, Kateryna D. Makova, and Oliver A. Ryder</i></p> <p>Index 323</p>

<p>“Equine Genomicsis an excellent text that compiles historical accomplishments in equine genetics and molecular biology, describes state-of-theart approaches to understanding the equine genome, and provides glimpses of where the field may go in the future . . . It is our responsibility to try to keep up, and I believe this book will help us do that.”  (<i>Journal of the American Veterinary Medical Association</i>, 15 June 2014)</p>

<p><b>Bhanu P. Chowdhary</b> is Professor, Faculty Fellow, and Associate Dean for Research and Graduate Studies in the Department of Veterinary Medicine and Biomedical Sciences at Texas A&M University, College Station, Texas.

<p><b>Equine Genomics</b> <p>Equine genetics has long been studied as a means of improving traits such as performance capabilities and coat color in horses. Dramatic advances in genomics and high-throughput DNA analysis technologies have significantly increased our understanding of the molecular biology of growth, development, and disease. <i>Equine Genomics</i> focuses on the significant advances in genome-mapping and genomic technologies and their application to the improvement of equine traits of economic significance. <p><i>Equine Genomics</i> provides broad-ranging coverage of advances in genome science as applied to horses. The opening chapters provide strong foundational information on defining the equine genome, the development of genetic linkage, physical and comparative maps, as well as whole genome sequences. The following several chapters then look at the underlying genetics of key traits, such as reproduction, coat color, performance, and a variety of key diseases impacting horses. The final chapter looks at equine mitochondrial DNA and its implication on equid evolution and genetic diversity. <p>A timely and vitally important resource, <i>Equine Genomics</i>, is an essential title for animal scientists, genomic researchers, veterinary scientists, equine breeders, and industry personnel.

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