Details

Templated Organic Synthesis


Templated Organic Synthesis


1. Aufl.

von: François Diederich, Peter J. Stang

133,99 €

Verlag: Wiley-VCH (D)
Format: PDF
Veröffentl.: 11.07.2008
ISBN/EAN: 9783527613533
Sprache: englisch
Anzahl Seiten: 431

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Beschreibungen

Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. <br> <br> The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.<br>
TEMPLATES IN SUPRAMOLECULAR CHEMISTRY<br /> Templates in Organic Synthesis: Definitions and Roles <br /> Molecular Imprinting: Templated Materials for Recognition and Catalysis <br /> Templated Synthesis of Catenanes and Rotaxanes <br /> Templated Synthesis of Carcerands, Containers, and Capsules <br /> Template-directed Nucleic Acid Synthesis<br /> TEMPLATES IN ORGANIC SYNTHESIS<br /> Tether-directed Remote Functionalization <br /> Regio- and Stereoselective Multiple Functionalization of Fullerenes <br /> Template-controlled Oligomerizations <br /> Templated Ring-closing Reactions <br /> Templated Stereoselective Synthesis Using Remote Covalent Tethers
<p><b>Francois Diederich</b> was born in 1952 in Luxembourg. He received his doctorate in 1979 from the University of Heidelberg and pursued postdoctoral studies at the University of California at Los Angeles. After his postdoctoral qualification at the Max-Planck-Institut fur medizinische Forschung, he joined the Department of Chemistry and Biochemistry at UCLA in 1985 where he became a full professor four years later. In 1992, he moved to the ETH Zurich as a member of the Department of Chemistry and Applied Biosciences. Professor Diederich's research interests, documented in more than 420 publications, range from medicinal chemistry with a focus on molecular recognition studies, to advanced fullerene and acetylene-based materials with novel optoelectronic properties.</p> <p><b>Peter J. Stang</b> is a German American chemist and Distinguished Professor of chemistry at the University of Utah. He has also been the editor of the Journal of the American Chemical Society. He is the author of more than 450 scientific publications and several books.</p>
Templated Organic Synthesis Edited by F. Diederich and P. J. Stang Located at the borderline of supramolecular and organic chemistry, template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authorative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereo-selectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. The editors and authors, all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.

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