Details

Mass Spectrometry for Lipidomics


Mass Spectrometry for Lipidomics

Methods and Applications
1. Aufl.

von: Michal Holcapek, Kim Ekroos

232,99 €

Verlag: Wiley-VCH
Format: EPUB
Veröffentl.: 07.03.2023
ISBN/EAN: 9783527836505
Sprache: englisch
Anzahl Seiten: 752

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Beschreibungen

Mass Spectrometry for Lipidomics <p><b>All-in-one guide to successful lipidomic analysis, combining the latest advances and best practices from academia, industry, and clinical research</b> <p><i>Mass Spectrometry for Lipidomics</i> presents a systematic overview of lipidomic analysis, covering established standards of lipid analysis, available technology, and key lipid classes, as well as applications in basic research, medicine, pharma, and the food industry. <p>Through connecting recent technological advances with key application areas, this unique guide bridges the gap between academia and industry by translating the vast body of knowledge that has been gained in the past decade into much-needed practical advice for novices as well as routine users. <p>Edited by the president and vice-president of the International Lipidomics Society with contributions from the top experts in lipid analysis, <i>Mass Spectrometry for Lipidomics</i> covers a wide range of key topics, including: <ul><li> Aspects of sample preparation, separation methods, different mass spectrometry modes, as well as identification and quantitation, including the use of bioinformatics tools for data analysis</li> <li> Identification, quantitation and profiling of lipids in different types of biological samples</li> <li> Analytical approaches for all major classes of biological lipids, from fatty acids to phospholipids to sterols</li> <li> Novel applications in biological research, clinical diagnostics, as well as food and crop science</li></ul> <p>For analytical chemists, biochemists, clinical chemists, and analytical laboratories and hospitals, <i>Mass Spectrometry for Lipidomics</i> presents a comprehensive and authoritative overview of the subject, with unmatched expertise from practicing professionals actively involved in the latest research.
PART 1: Introduction<br> The International Lipidomics Society<br> Standardization efforts in lipidomics<br> <br> PART 2: Analytical methodologies in lipidomics<br> Preanalytical phase, extraction protocols, and robotization<br> Shotgun electrospray mass spectrometry<br> Liquid chromatography- and supercritical fluid chromatography-mass spectrometry<br> Mass spectrometry imaging of lipids in tissues<br> Ion mobility spectrometry<br> Structural characterization using advanced mass spectrometry approaches<br> Lipidomic identification<br> Lipidomic quantitation<br> Bioinformatics, softwares, and databases<br> <br> PART 3: Lipidomic analysis according to lipid categories and classes<br> Glycerophospholipids<br> Sphingolipids<br> Glycerolipids<br> Sterol lipids<br> Fatty acids<br> Oxylipins<br> Bile acids<br> <br> PART 4: Lipidomic applications<br> Large scale biobank lipidomics <br> Lipidomics in cancer<br> Lipidomics in clinical diagnostics<br> Lipidomics in food industry and nutrition<br> Lipidomics in plant science<br> Integration of lipidomics with other omics approaches<br> Fluxomics in lipidomics<br> Lipidomics in aging and Alzheimer's disease<br> Lipidomics in CVD<br> Lipidomics in pharma research<br> Lipidomics in membrane biology<br> Lipidomics in cell biology
<p><b>Michal Holèapek</b> obtained his Ph.D. at the University of Pardubice (Czech Republic), where he is now a full professor of analytical chemistry. His research focus is mass spectrometry and its coupling with liquid chromatography and supercritical fluid chromatography. He is the current vice-president for conferences of the International Lipidomics Society.</p> <p><b>Kim Ekroos</b> is the founder and CEO of Lipidomics Consulting Ltd. He received his Ph.D. degree in biology from the Technical University in Dresden (Germany). He is the current president of the International Lipidomics Society.</p>
<p><b>All-in-one guide to successful lipidomic analysis, combining the latest advances and best practices from academia, industry, and clinical research</b> <p><i>Mass Spectrometry for Lipidomics</i> presents a systematic overview of lipidomic analysis, covering established standards of lipid analysis, available technology, and key lipid classes, as well as applications in basic research, medicine, pharma, and the food industry. <p>Through connecting recent technological advances with key application areas, this unique guide bridges the gap between academia and industry by translating the vast body of knowledge that has been gained in the past decade into much-needed practical advice for novices as well as routine users. <p>Edited by the president and vice-president of the International Lipidomics Society with contributions from the top experts in lipid analysis, <i>Mass Spectrometry for Lipidomics</i> covers a wide range of key topics, including: <ul><li> Aspects of sample preparation, separation methods, different mass spectrometry modes, as well as identification and quantitation, including the use of bioinformatics tools for data analysis</li> <li> Identification, quantitation and profiling of lipids in different types of biological samples</li> <li> Analytical approaches for all major classes of biological lipids, from fatty acids to phospholipids to sterols</li> <li> Novel applications in biological research, clinical diagnostics, as well as food and crop science</li></ul> <p>For analytical chemists, biochemists, clinical chemists, and analytical laboratories and hospitals, <i>Mass Spectrometry for Lipidomics</i> presents a comprehensive and authoritative overview of the subject, with unmatched expertise from practicing professionals actively involved in the latest research.

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