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<p>List of Contributors xiii</p> <p>Foreword xix</p> <p>Preface xxi</p> <p>About the Companion Website xxiii</p> <p><b>Section 1 Basic Science 1</b></p> <p>1 Introduction 3<br /><i>Somesh Gupta and Nanja van Geel</i></p> <p>2 Melanocyte and Melanogenesis: Applied Anatomy and Physiology 9<br /><i>Reinhart Speeckaert and Nanja van Geel</i></p> <p>3 Epidemiology of Vitiligo 15<br /><i>Nader Aboul</i><i>‐</i><i>Fettouh and Amit G. Pandya</i></p> <p>4 Pathogenesis of Vitiligo 19<br /><i>John E. Harris</i></p> <p>5 Understanding the Mechanisms of Repigmentation in Vitiligo 27<br /><i>Ravinder Kumar, Davinder Parsad, and Amrinder J. Kanwar</i></p> <p><b>Section 2 Clinical Science 33</b></p> <p>6 Classification and Clinical Features of Vitiligo 35<br /><i>Sang Ho Oh and Seung</i><i>‐</i><i>Kyung Hann</i></p> <p>7 Outcome Measures for Vitiligo 49<br /><i>Brian Clinton, Viktoria Eleftheriadou, Nanja van Geel, Laila Benzekri, Amit G. Pandya, and Khaled Ezzedine</i></p> <p>8 Evaluation and Treatment of the Psychosocial Burden of Vitiligo 61<br /><i>Vishal Gupta and M. Ramam</i></p> <p>9 Patient Support, Education, and Compliance 69<br /><i>Richard H. Huggins, Jackie Gardner, and Amit G. Pandya</i></p> <p>10 Goals of Vitiligo Treatment, and Evidence‐Based Practice Guidelines for Medical and Surgical Management 77<br /><i>Kevin Prier and Amit G. Pandya</i></p> <p>11 The Concept of Stability of Vitiligo and Stabilization Therapies 81<br /><i>Anuradha Bishnoi and Davinder Parsad</i></p> <p><b>Section 3 Phototherapy 91</b></p> <p>12 Narrow‐Band Ultraviolet B Phototherapy in Vitiligo 93<br /><i>Narumol Silpa</i><i>‐</i><i>archa and Henry W. Lim</i></p> <p>13 UVA‐Based Phototherapy: PUVA, PUVA‐Sol, and UVA1 Phototherapy 105<br /><i>Ljubomir B. Novaković</i></p> <p>14 Targeted Phototherapy in Vitiligo 113<br /><i>Mohammed Al</i><i>‐</i><i>Jamal, James L. Griffith, Iltefat H. Hamzavi, and Henry W. Lim</i></p> <p><b>Section 4 Medical Management 123</b></p> <p>15 Immunomodulators and Immunosuppressives in Vitiligo Treatment 125<br /><i>Anuradha Bishnoi and Davinder Parsad</i></p> <p>16 Topical Glucocorticoids, Topical Calcineurin Inhibitors, and Topical Vitamin D3 Analogs 133<br /><i>Sai Yee Chuah and Boon Kee Goh</i></p> <p>17 Other Therapies in Vitiligo 141<br /><i>Narumol Silpa</i><i>‐</i><i>archa, James L. Griffith, Iltefat H. Hamzavi, and Pearl E. Grimes</i></p> <p>18 Biologic Therapies for Vitiligo 151<br /><i>Pablo Michel and Amit G. Pandya</i></p> <p>19 Evidence Toward Integrated Management of Vitiligo, Combining Ayurveda and Homeopathy with Modern Dermatology 159<br /><i>Saravu R. Narahari, Madhur G. Aggithaya, Kuthaje S. Bose, and Kodimoole S. Prasanna</i></p> <p><b>Section 5 Surgical Therapies: History, Patient Selection, and Classification 171</b></p> <p>20 History and Chronology of Development of Surgical Therapies for Vitiligo 173<br /><i>Koushik Lahiri and Abhishek De</i></p> <p>21 Patient Selection, Pre‐ and Postoperative Information in Surgical Therapies for Vitiligo 185<br /><i>Nanja van Geel and Mats J. Olsson</i></p> <p>22 Classification of Surgical Therapies in Vitiligo 193<br /><i>James L. Griffith, Mohammed Al</i><i>‐</i><i>Jamal, and Iltefat H. Hamzavi</i></p> <p><b>Section 6 Surgical Therapies: Tissue Grafting 209</b></p> <p>23 Minigrafting for Vitiligo 211<br /><i>Koushik Lahiri</i></p> <p>24 Suction Blister Epidermal Grafting 225<br /><i>Savita Yadav and Somesh Gupta</i></p> <p>25 Thin and Ultra‐Thin Skin Grafts for Vitiligo 241<br /><i>Imran Majid</i></p> <p>26 Treatment of Leukoderma by Transplantation of Ultra‐Thin Epidermal Sheets<br />Using a Motorized Dermatome 249<br /><i>Mats J. Olsson</i></p> <p>27 Mesh Grafts for Vitiligo 257<br /><i>Chakravarthi R. Srinivas and Reena Rai</i></p> <p>28 Smash Grafting 261<br /><i>Sumit Kar, Ajay Krishnan, and Sudhir Singh</i></p> <p>29 Therapeutic Needling and Needling Micrografting 267<br /><i>Khalifa E. Sharquie and Adil A. Noaimi</i></p> <p>30 Complications and Limitations of Melanocyte Transplantation 273<br /><i>Yvon Gauthier and Laila Benzekri</i></p> <p><b>Section 7 Surgical Therapies: Cellular Grafting 279</b></p> <p>31 Treatment of Leukoderma by Transplantation of Basal Cell Layer Suspension 281<br /><i>Mats J. Olsson</i></p> <p>32 Non‐Cultured Extracted Follicle Outer Root Sheath Cell Suspension Transplantation 293<br /><i>Kanika Sahni and Somesh Gupta</i></p> <p>33 Long‐Term Results of Non‐Cultured Epidermal Cellular Grafting in Vitiligo 299<br /><i>Nanja van Geel, Sofie De Schepper, Hilde Lapeere, Barbara Boone, Boon Kee Goh, and Reinhart Speeckaert</i></p> <p>34 Simplified Non‐Cultured Cellular Grafting 303<br /><i>Boon Kee Goh</i></p> <p>35 Novel Methods of Preparing Epidermal Cell Suspension for Transplantation in Vitiligo 309<br /><i>Vishal Gupta, Sanjeev Gupta, Kanika Sahni, and Somesh Gupta</i></p> <p>36 Management of Vitiligo: Setting Up a Tissue Culture Laboratory 317<br /><i>Rafał Czajkowski, Małgorzata Maj, and Tomasz Drewa</i></p> <p>37 Treatment of Leukoderma by Transplantation of Cultured Autologous Melanocytes 323<br /><i>Mats J. Olsson</i></p> <p>38 Transplantation of In‐Vitro‐Cultured Epithelial Grafts for Vitiligo and Piebaldism 337<br /><i>Liliana Guerra, Sergio Bondanza, and Desanka Raskovic</i></p> <p>39 Application of Lasers for Abrasion in Transplantation Procedures for Vitiligo 351<br /><i>Gwang Seong Choi</i></p> <p>40 Cell Delivery on Recipient Skin 357<br /><i>Thomas Hunziker</i></p> <p>41 Safety Concerns in Transplantation of In‐Vitro‐Cultured Cellular Grafts 363<br /><i>Liliana Guerra, Elena Dellambra, Patrizia Paterna, and Somesh Gupta</i></p> <p><b>Section 8 Special Issues in Medical and Surgical Therapies 369</b></p> <p>42 Surgical Management of Vitiligo of Lips, Eyelids, and Genitals 371<br /><i>Riti Bhatia and Somesh Gupta</i></p> <p>43 Surgical Management of Acral Vitiligo 389<br /><i>Munish Paul</i></p> <p>44 Surgical Management of Leukotrichia 401<br /><i>Amrendra Kumar</i></p> <p>45 Surgical Treatments of Leukodermas Other Than Vitiligo Vulgaris 407<br /><i>Mats J. Olsson</i></p> <p>46 Ethnic Issues in Management of Vitiligo and Sun Protection 417<br /><i>Haneol S. Jeong, Michelle Rodrigues, and Amit G. Pandya</i></p> <p>47 Management Issues for Vitiligo in Children and Pregnant Women 427<br /><i>Freya Van Driessche and Nanette Silverberg</i></p> <p>48 Combination Treatments for Vitiligo 439<br /><i>Anuradha Bishnoi and Davinder Parsad</i></p> <p>49 Micropigmentation 451<br /><i>Gurvinder P. Thami</i></p> <p>50 Camouflage in Vitiligo 459<br /><i>Chakravarthi R. Srinivas, Pradeep Balasubramanian, and C.K. Shashidharan Nair</i></p> <p>51 Depigmentation Treatment for Vitiligo: Bleaching Cream, Laser, and Cryotherapy 469<br /><i>Nanja van Geel and Monique R.T.M. Thissen</i></p> <p>52 Future Directions in the Treatment of Vitiligo 475<br /><i>Vishal Gupta and Somesh Gupta</i></p> <p>53 Informed Consent 491<br /><i>Mats J. Olsson</i></p> <p>Index 495</p> <p> </p>

<p><b>About the Editors</b> <p><b>Somesh Gupta, MD, DNB, MNAMS,</b> Professor, Department of Dermatology & Venereology, All India Institute of Medical Sciences, New Delhi, India <p><b>Mats J. Olsson, MD, PhD,</b> CEO, ParkCell AB and President, International Vitiligo Center, Uppsala, Sweden <p><b>Davinder Parsad, MD,</b> Professor, Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh, India <p><b>Henry W. Lim, MD,</b> Chair Emeritus, Department of Dermatology and Senior Vice President for Academic Affairs, Henry Ford Health System. Past President, American Academy of Dermatology, Detroit, USA <p><b>Nanja van Geel, MD, PhD,</b> Professor, Department of Dermatology, Ghent University Hospital, Ghent, Belgium <p><b>Amit G. Pandya, MD,</b> Professor, Department of Dermatology, University of Texas, Southwestern Medical Center, Dallas, USA

<p><b>PRACTICAL GUIDANCE BASED ON EXPERT EXPERIENCE AND EVIDENCE FOR DEVELOPING MANAGEMENT STRATEGIES FOR VITILIGO</b> <p>This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world's population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case. <p>Management of vitiligo is challenging and requires a multipronged approach. <i>Vitiligo: Medical and Surgical Management</i> is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. <i>Vitiligo: Medical and Surgical Management</i> takes an evidenced-based approach to the disease's treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more. <ul> <li>Thoroughly guides those involved in the clinical aspects of vitiligo</li> <li>Aids diagnosis and classification of severity</li> <li>Balances evidence and experience</li> <li>Compiled by world-leading expert editors</li> </ul> <p>Comprehensive in nature, <i>Vitiligo: Medical and Surgical Management</i> contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.

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