Details

Virulence Mechanisms of Bacterial Pathogens

ASM Books 5. Aufl.

von: Indira T. Kudva, Nancy A. Cornick, Paul J. Plummer, Qijing Zhang, Tracy L. Nicholson, John P. Bannantine, Bryan H. Bellaire
123,99 €
Verlag:	ASM Press
Format:	EPUB
Veröffentl.:	01.06.2016
ISBN/EAN:	9781683673200
Sprache:	englisch

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Beschreibungen

Titelbeschreibung

Ground-breaking overview of an enduring topic Despite the use of antibiotics, bacterial diseases continue to be a critical issue in public health, and bacterial pathogenesis remains a tantalizing problem for research microbiologists. This new edition of Virulence Mechanisms of Bacterial Pathogens broadly covers the knowledge base surrounding this topic and presents recently unraveled bacterial virulence strategies and cutting-edge therapies. A team of editors, led by USDA scientist Indira Kudva, compiled perspectives from experts to explain the wide variety of mechanisms through which bacterial pathogens cause disease: the host interface, host cell enslavement, and bacterial communication, secretion, defenses, and persistence. A collection of reviews on targeted therapies rounds out the seven sections of this unique book. The new edition provides insights into some of the most recent advances in the area of bacterial pathogenesis, including <ul> <li>how metabolism shapes the host-pathogen interface</li> <li>interactions across species and genera</li> <li>mechanisms of the secretion systems</li> <li>evasion, survival, and persistence mechanisms</li> <li>new therapies targeting various adaptive and virulence mechanisms of bacterial pathogens</li> </ul> Written to promote discussion, extrapolation, exploration, and multidimensional thinking, Virulence Mechanisms of Bacterial Pathogens serves as a textbook for graduate courses on bacterial pathogenesis and a resource for specialists in bacterial pathogenicity, such as molecular biologists, physician scientists, infectious disease clinicians, dental scientists, veterinarians, molecular biologists, industry researchers, and technicians.

Inhaltsverzeichnis

Contributors ix Preface xv Acknowledgments xvii I. Bacterial-Host Interface Section Editor: Nancy A. Cornick 1 Evolution of Bacterial Pathogens within the Human Host 3 Kimberly A. Bliven and Anthony T. Maurelli 2 Bacterial Metabolism Shapes the Host–Pathogen Interface 15 Karla D. Passalacqua, Marie-Eve Charbonneau, and Mary X.D. O’Riordan 3 Iron Acquisition Strategies of Bacterial Pathogens 43 Jessica R. Sheldon, Holly A. Laakso, and David E. Heinrichs II. Bacterial Communication and Virulence Section Editor: Paul J. Plummer 4 Sociomicrobiology and Pathogenic Bacteria 89 Joao B. Xavier 5 Candida-Bacteria Interactions: Their Impact on Human Disease 103 Devon L. Allison, Hubertine M. E. Willems, J.A.M.S. Jayatilake, Vincent M. Bruno, Brian M. Peters, and Mark E. Shirtliff 6 Microbial Endocrinology in the Pathogenesis of Infectious Disease 137 Mark Lyte 7 Small RNAs in Bacterial Virulence and Communication 169 Sarah L. Svensson and Cynthia M. Sharma III. Bacterial Secretion Systems Section Editor: Indira T. Kudva 8 Bacterial Secretion Systems: An Overview 215 Erin R. Green and Joan Mecsas 9 The Structure and Function of Type III Secretion Systems 241 Ryan Q. Notti and C. Erec Stebbins 10 Mechanism and Function of Type IV Secretion During Infection of the Human Host 265 Christian Gonzalez-Rivera, Minny Bhatty, and Peter J. Christie 11 Type V Secretion Systems in Bacteria 305 Enguo Fan, Nandini Chauhan, D. B. R. K. Gupta Udatha, Jack C. Leo, and Dirk Linke 12 The Versatile Type VI Secretion System 337 Christopher J. Alteri and Harry L.T. Mobley 13 Type VII Secretion: A Highly Versatile Secretion System 357 Louis S. Ates, Edith N. G. Houben, and Wilbert Bitter IV. Bacterial Defenses Section Editor: Qijing Zhang 14 Stress Responses, Adaptation, and Virulence of Bacterial Pathogens During Host Gastrointestinal Colonization 387 Annika Flint, James Butcher, and Alain Stintzi 15 Bacterial Evasion of Host Antimicrobial Peptide Defenses 413 Jason N. Cole and Victor Nizet 16 Antigenic Variation in Bacterial Pathogens 445 Guy H. Palmer, Troy Bankhead, and H. Steven Seifert 17 Mechanisms of Antibiotic Resistance 481 Jose M. Munita and Cesar A. Arias V. Bacterial Persistence: Within and Between Hosts Section Editor: Tracy L. Nicholson 18 Chronic Bacterial Pathogens: Mechanisms of Persistence 515 Mariana X. Byndloss and Renee M. Tsolis 19 The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response 529 Alexandra E. Paharik and Alexander R. Horswill 20 Surviving Between Hosts: Sporulation and Transmission 567 Michelle C. Swick, Theresa M. Koehler, and Adam Driks 21 Staying Alive: Vibrio cholerae’s Cycle of Environmental Survival, Transmission, and Dissemination 593 Jenna G. Conner, Jennifer K. Teschler, Christopher J. Jones, and Fitnat H. Yildiz VI. Host Cell Enslavement by Intracellular Bacteria Section Editor: John P. Bannantine 22 Hijacking and Use of Host Lipids by Intracellular Pathogens 637 Alvaro Toledo and Jorge L. Benach 23 Contrasting Lifestyles Within the Host Cell 667 Elizabeth Di Russo Case and James E. Samuel 24 Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms 693 Valérie Poirier and Yossef Av-Gay 25 Cellular Exit Strategies of Intracellular Bacteria 715 Kevin Hybiske and Richard Stephens VII. Targeted Therapies Section Editor: Bryan H. Bellaire 26 Novel Targets of Antimicrobial Therapies 741 Sarah E. Maddocks 27 Innovative Solutions to Sticky Situations: Antiadhesive Strategies for Treating Bacterial Infections 753 Zachary T. Cusumano, Roger D. Klein, and Scott J. Hultgren 28 The Role of Biotin in Bacterial Physiology and Virulence: A Novel Antibiotic Target for Mycobacterium tuberculosis 797 Wanisa Salaemae, Grant W. Booker, and Steven W. Polyak 29 Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases 823 Jan S. Suchodolski and Albert E. Jergens Index 843

Back cover copy

Virulence Mechanisms of Bacterial Pathogens Fifth Edition Ground-breaking overview of an enduring topic Despite the use of antibiotics, bacterial diseases continue to be a critical issue in public health, and bacterial pathogenesis remains a tantalizing problem for research microbiologists. This new edition of Virulence Mechanisms of Bacterial Pathogens broadly covers the knowledge base surrounding this topic and presents recently unraveled bacterial virulence strategies and cutting-edge therapies. A team of editors, led by USDA scientist Indira Kudva, compiled perspectives from experts to explain the wide variety of mechanisms through which bacterial pathogens cause disease: the host interface, host cell enslavement, and bacterial communication, secretion, defenses, and persistence. A collection of reviews on targeted therapies rounds out the seven sections of this unique book. The new edition provides insights into some of the most recent advances in the area of bacterial pathogenesis, including <ul> <li>how metabolism shapes the host-pathogen interface</li> <li>interactions across species and genera</li> <li>mechanisms of the secretion systems</li> <li>evasion, survival, and persistence mechanisms</li> <li>new therapies targeting various adaptive and virulence mechanisms of bacterial pathogens</li> </ul> Written to promote discussion, extrapolation, exploration, and multidimensional thinking, Virulence Mechanisms of Bacterial Pathogens serves as a textbook for graduate courses on bacterial pathogenesis and a resource for specialists in bacterial pathogenicity, such as molecular biologists, physician scientists, infectious disease clinicians, dental scientists, veterinarians, molecular biologists, industry researchers, and technicians.