Details

The Peripheral T-Cell Lymphomas


The Peripheral T-Cell Lymphomas


1. Aufl.

von: Owen A. O'Connor, Won Seog Kim, Pier L. Zinzani

152,99 €

Verlag: Wiley-Blackwell
Format: PDF
Veröffentl.: 19.02.2021
ISBN/EAN: 9781119671329
Sprache: englisch
Anzahl Seiten: 416

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Beschreibungen

<p><b>The first text dedicated to peripheral T-cell lymphomas and their classification, diagnosis, and management </b></p> <p>Peripheral T-cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represents 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. </p> <p>The first book of its kind, <i>The Peripheral T-Cell Lymphomas</i> presents a far-reaching survey of this complex and rare group of blood cancers. Featuring contributions from thought-leaders concerned with all aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: </p> <ul> <li>Covers the biological basis, epidemiology, classification, and treatment of PTCL </li> <li>Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL </li> <li>Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation </li> <li>Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations </li> <li>Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL </li> </ul> <p>Reflecting the unique epidemiology and genetic diversity of the PTCL, <i>The Peripheral T-Cell Lymphomas</i> is an indispensable source of data, insight, and references for the medical community, particularly those working in oncology and hematology.  </p>
<p>List of contributors to be generated by the copy editor</p> <p>Part 1: Biological Basis of the Peripheral T-Cell Lymphomas</p> <p>1 Fundamentals T-Cell Lymphocyte Biology</p> <p>Claudio Tripodo, Stefano Pilleri</p> <p>2 Mechanisms of T-cell Lymphomagenesis</p> <p>François Lemonnier, Philippe Gaulard, Laurence de Leval</p> <p>3 Epigenetics of T-cell Lymphoma</p> <p>H. Miles Prince, Jasmine Zain, Anas Younes, Sean Whittaker, Owen O’Connor, Sean Harrop</p> <p>4 Animal Models of T-cell Lymphoma</p> <p>Keiichiro Hattori, Raksha Shrestha, Tatsuhiro Sakamoto, Manabu Kusakabe, Mamiko Sakata-Yanagimoto</p> <p>Part 2: Epidemiology and Classification of the PTCL</p> <p>5 The Geographic Distribution of the PTCL: Global Epidemiology</p> <p>Amulya Yellala, Avyakta Kallam, James Armitage</p> <p>6 Classification of the Peripheral T-Cell Lymphomas</p> <p>Neval Ozkaya, Elaine Jaffee</p> <p>7 Molecular Classification of the PTCLs</p> <p>Tyler A. Herek, Javed Iqbal</p> <p>Part 3: Discrete Clinical Subtypes of PTCL (Unique Epidemiology, Therapy and Management)</p> <p>8 Peripheral T-Cell Lymphoma – Not Otherwise Specified</p> <p>Nora Bennani, Stephen Ansell</p> <p>9 Angioimmunoblastic T-cell Lymphoma (AITL)</p> <p>Jehan Dupuis, Franck Morschhauser</p> <p>10 The Spectrum of Anaplastic Large Cell Lymphoma</p> <p>Jianping Kong, Andrew Feldman</p> <p>11 HTLV-1-Positive Adult T-Cell Leukemia-Lymphoma (ATL)</p> <p>Wataru Munakata, Kensei Tobinai</p> <p>12 Natural Killer/T Cell Lymphomas</p> <p>S.J. Kim, R. Suzuki, A. Jaccard, S.T. Lim, Won Seog Kim</p> <p>13 T-Prolymphocytic Leukemia (T-PLL)</p> <p>Dima El-Sharkawi, Claire Deardon</p> <p>14 Large Granular Lymphocytes Leukemia (LGL)</p> <p>Karolina H. Dziewulska, Katharine B. Moosic, HeeJin Cheon, Kristine C. Olson, David J. Feith, Thomas P. Loughran, Jr.</p> <p>15 Gamma Delta T-cell Lymphomas</p> <p>Francine Foss, Aadil Ahmed, Mina Xu</p> <p>16 Enteropathy Associated T-Cell Lymphoma and Monomorphic Epitheliotropic Intestinal T-cell lymphoma</p> <p>Craig R. Soderquist, Jennifer Shingleton, Sandeep Dave, Govind Bhagat</p> <p>17 Hepatosplenic T-Cell Lymphomas</p> <p>Robert N. Stuver, Mwanasha Merrill, Salvia Jain</p> <p>18 Cutaneous T-Cell Lymphoma</p> <p>Alejandro Ariel Gru, Bethanie Rooke, Kevin Molloy, Julia Scarsbrick</p> <p>19 Other Rare Subtypes of PTCL</p> <p>Pier Paolo Picaluga</p> <p>Part 4: Treatment of the PTCL</p> <p>20 Standard Front-line Therapies</p> <p>Raphael Koch, Lorenz Truemper</p> <p>21 Approved Agents in the Relapsed or Refractory Setting, Excluding Brentuximab vedotin</p> <p>Helen Ma, Owen A. O’Connor</p> <p>22 The Role for Autologous Stem Cell Transplantation (ASCT) in Peripheral T Cell Lymphomas (PTCL)</p> <p>Juan Alejandro Ospina, H. Martinez-Cordero, J. Enciso, H. Idrobo</p> <p>23 Allogeneic Stem Cell Transplantion</p> <p>Anna Dodero, Paolo Corradini</p> <p>24 Emerging Immunotherapy Approaches in Peripheral T-Cell Lymphomas</p> <p>Barbara Pro, Andrei Shustov</p> <p>25 Emerging New Small Molecules in Peripheral T-Cell Lymphomas</p> <p>Alessandro Broccoli, Pier Luigi Zinzani</p> <p>Part 5: Future Directions</p> <p>26 The Value and Relevance of T-cell Lymphoma Registries</p> <p>Tetiana Skrypets, Martina Manni, Monica Civallero, Iryna Kriachok, Massimo Federico</p> <p>27 Innovative Chemotherapy-Free Approaches for the Treatment of PTCL </p> <p>Enrica Marchi, Ahmed Sawas, Helen Ma, Luigi Scotto, Francesca Montanari</p> <p>28 Global Collaborations</p> <p>Dejan Radjeski, Eliza Hawke, Owen A. O’Connor, Pier Luigi Zinzani, WonSeog Kim, Enrica Marchi</p>
<p><b>Owen A. O’Connor, MD</b><b>, PhD </b>is<b> </b>American Cancer Society Research Professor, Professor of Medicine and Experimental Therapeutics<b>, </b>and<b> </b>Founding Director of the Center for Lymphoid Malignancies, Columbia University Medical Center, New York, NY, USA. </p> <p><b>Won Seog Kim, MD</b><b>, PhD </b>is Professor of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.  </p> <p><b>Pier Luigi Zinzani, MD</b><b>, PhD </b>is<b> </b>Professor of Hematology<b>, </b>Director of Lymphoma and CLL Unit, and<b> </b>Chief of Phase I clinical trials<b>, </b>Institute of Hematology, University of Bologna, Bologna, Italy. </p>

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