Details

T Cell Subsets in Infectious and Autoimmune Diseases


T Cell Subsets in Infectious and Autoimmune Diseases


Novartis Foundation Symposia, Band 195 1. Aufl.

von: Derek J. Chadwick, Gail Cardew

121,99 €

Verlag: Wiley
Format: PDF
Veröffentl.: 30.04.2008
ISBN/EAN: 9780470514856
Sprache: englisch
Anzahl Seiten: 272

DRM-geschütztes eBook, Sie benötigen z.B. Adobe Digital Editions und eine Adobe ID zum Lesen.

Beschreibungen

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in autoimmune diseases.
Partial table of contents: <p>Differentiation and Tolerance of CD4<sup>+</sup> T Lymphocytes (A. Abbas, <i>et al.</i>).</p> <p>Differentiation of Subsets of CD4<sup>+</sup> and CD8<sup>+</sup> T Cells (T. Mosmann, <i>et al.</i>).</p> <p>Role for CD30 Antigen in Human T Helper 2-Type Responses. (S. Romagnani) Regulation of T Lymphocyte Subsets (F. Fitch, <i>et al.</i>).</p> <p>The Development of Effector T Cell Subsets in Murine <i>Leishmania Major</i> Infection (R. Locksley, <i>et al.</i>).</p> <p>Cytokines in Immune Regulation/Pathogenesis in HIV Infection (G. Shearer, <i>et al.</i>).</p> <p>Regulation of CD4<sup>+</sup> T Cell Differentiation (T. Nakamura, <i>et al.</i>).</p> <p>The Role of Subsets of CD4<sup>+</sup> T Cells in Autoimmunity (D. Fowell, <i>et al.</i>).</p> <p>Nitric Oxide in Infectious and Autoimmune Diseases (F. Liew).</p> <p>Final Discussion.</p> <p>Indexes.</p>
<p><b>Derek J. Chadwick</b> and <b>Gail Cardew</b> are editors for <i>T Cell Subsets in Infectious and Autoimmune Diseases</i> and other scientific titles.</p>
Mature T cells are classified on the basis of their surface marker proteins, such as CD4 and CD8. CD4<sup>+</sup> and CD8<sup>+</sup> cells recognize antigens associated with major histocompatibility complex class II and class I molecules, respectively, and they can both be further classified into subgroups. The division of CD4<sup>+</sup> T cells into T helper 1 (Th1) and Th2 cells is based on the secretion of distinct patterns of cytokines, and the resulting polarized Th1 and Th2 responses play different roles in protection and the promotion of different immunopathological reactions. In contrast, CD8<sup>+</sup> T cells are strongly cytotoxic; however, they can also secrete Th1-like or Th2-like cytokine profiles. This suggests that there is an increasingly complex network of cytokine regulatory patterns which are produced in response to, and specifically tailored to, different offending agents. This book contains contributions from a diverse group of scientists and clinicians working on T cells. Specific topics include: the differentiation and regulation of T cell subsets; their roles in bacterial, protozoan, viral and autoimmune diseases; and the effector mechanisms employed by these subsets of cells. Vaccine development, memory, anergy and allergy are also discussed.

Diese Produkte könnten Sie auch interessieren:

Zukunftstechnologie Tissue Engineering
Zukunftstechnologie Tissue Engineering
von: Will W. Minuth, Raimund Strehl, Karl Schumacher
PDF ebook
114,99 €
Biologische Bodensanierung
Biologische Bodensanierung
von: Kassem Alef
PDF ebook
40,99 €
Zukunftstechnologie Tissue Engineering
Zukunftstechnologie Tissue Engineering
von: Will W. Minuth, Raimund Strehl, Karl Schumacher
EPUB ebook
114,99 €