Details

Spiro Compounds


Spiro Compounds

Synthesis and Applications
1. Aufl.

von: Ramon Rios Torres

165,99 €

Verlag: Wiley
Format: EPUB
Veröffentl.: 15.02.2022
ISBN/EAN: 9781119567653
Sprache: englisch
Anzahl Seiten: 464

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Beschreibungen

<b>SPIRO COMPOUNDS</b> <p><b>A comprehensive treatment of the latest research in, and applications of, spiro compounds </b> <p><i>Spiro Compounds: Synthesis and Applications</i> combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, <i>Spiro Compounds</i> delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies. <p> With a special focus on the mechanisms of the reactions that lead to the synthesis of spiro compounds, chapters in the book cover topics such as: <ul><li>The history, significance, and unique properties of spiro compounds</li> <li>The most important methodologies for their synthesis</li> <li>The applications of spiro compounds in organic chemistry, biology, drug discovery</li> <li>The most important syntheses of natural products bearing a spiro ring</li></ul> <p>Perfect for academic and industrial chemists, this comprehensive discussion of spirocycles is an indispensable resource for those practicing in the field.
<p>Prelims</p> <p>Table of Contents</p> <p>List of Contributors</p> <p>Preface</p> <p>CHAPTER 1. Spiro Compounds: A Brief Story</p> <p>CHAPTER 2. Selected Applications of Spirocycles in Medicinal Chemistry</p> <p>CHAPTER 3. Recent Advances in the Asymmetric Synthesis of Spiro Compounds through Cycloadditions </p> <p>CHAPTER 4. Design and Synthesis of Spirocycles via Olefin Metathesis </p> <p>CHAPTER 5. Spirooxindoles, synthesis via organocatalytic processes</p> <p>CHAPTER 6. Spirooxindole synthesis by organometallic processes</p> <p>CHAPTER 7. Enantioselective synthesis of spiro heterocycles</p> <p>CHAPTER 8. Enantioselective synthesis of all carbon spiro compounds</p> <p>CHAPTER 9. Transition-Metal-Catalyzed Dearomative Spiroannulation Reactions</p> <p>CHAPTER 10. Carbocyclic Spiro Compounds Occupying Higher Dimensions: Benzoannelated [5.5.5.5]Fenestranes and Beyond</p> <p>CHAPTER 11. The synthesis of natural products containing spirocycles</p> <p>Index</p>
<p><b>Ramon Rios Torres, PhD</b> is Associate Professor in Organic Chemistry at the University of Southampton. He is the author of more than 130 papers, 18 chapters in chemical books, and a patent. Dr. Rios has edited two books with Wiley: <i>Stereoselective Organocatalysis: Bond Formation Methodologies</i> and <i>Activation Modes and The Pauson-Khand Reaction: Scope, Variations and Applications.</i></p>
<p><b>A comprehensive treatment of the latest research in, and applications of, spiro compounds </b></p> <p><i>Spiro Compounds: Synthesis and Applications</i> combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, <i>Spiro Compounds</i> delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies. <p> With a special focus on the mechanisms of the reactions that lead to the synthesis of spiro compounds, chapters in the book cover topics such as: <ul><li>The history, significance, and unique properties of spiro compounds</li> <li>The most important methodologies for their synthesis</li> <li>The applications of spiro compounds in organic chemistry, biology, drug discovery</li> <li>The most important syntheses of natural products bearing a spiro ring</li></ul> <p>Perfect for academic and industrial chemists, this comprehensive discussion of spirocycles is an indispensable resource for those practicing in the field.

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