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<p>1 Transfusion in the New Millennium</p> <p>Ennio C. Rossi, Toby L. Simon</p> <p>Section I. Contemporary Issues in Donation and Transfusion</p> <p>2 Patient Blood Management</p> <p>Darrell J. Triulzi, Mark H. Yazer, J.H. Waters</p> <p>3 Clinical and Technical Aspects of Blood Administration</p> <p>Eric Gehrie, Jocelyn Chandler, Edward Snyder</p> <p>4 Recruitment and Screening of Donors and the Collection, Processing, and Testing of Blood</p> <p>Kendall P. Crookston, Aaron E. Pritchard, Toby L. Simon</p> <p>5 Adverse Reactions and Iron Deficiency after Blood Donation</p> <p>Anne F. Eder, Joseph E. Kiss</p> <p>6 Donor Vigilance and Hemovigilance</p> <p>Øystein Flesland, Johannna C. Wiersum-Osselton</p> <p>7 Global Perspective on Ensuring Blood and Blood Product Safety and Availability</p> <p>Paul D. Mintz, Mark J. Weinstein</p> <p>Section II. Blood Components and Derivatives</p> <p>Part I. Red Blood cells</p> <p>8 Red Blood Cell Production and Kinetics</p> <p>Mark J. Koury</p> <p>9 Red Blood Cell Metabolism, Preservation and Oxygen Delivery</p> <p>John R. Hess, Bjarte G. Solheim</p> <p>10 Anemia and Red Blood Cell Transfusion</p> <p>Jeffrey L. Carson, Paul Hébert</p> <p>11 Sickle Cell Anemia, Thalassemia and Congenital Hemolytic Anemias</p> <p>Keith Quirolo, Elliott Vichinsky</p> <p>12 Autoimmune Hemolytic Anemias and Paroxysmal Nocturnal Hemoglobinuria</p> <p>Andrea M. McGonigle, Paul M. Ness, Karen E. King</p> <p>13 Carbohydrate Blood Groups</p> <p>Laura Cooling</p> <p>14 Rh and LW Blood Groups</p> <p>Connie M. Westhoff, Don L. Siegel</p> <p>15 Other Protein Blood Groups</p> <p>Jill R. Storry</p> <p>16 Red Cell Immunology and Compatibility Testing</p> <p>Connie M. Westhoff</p> <p>Part II: Platelets</p> <p>17 Platelet Production and Kinetics</p> <p>Christopher A. Tormey, Henry M. Rinder</p> <p>18 Platelet Immunology and Alloimmunization</p> <p>Janice G. McFarland</p> <p>19 Preparation, Preservation, and Storage of Platelet Concentrates</p> <p>Ralph R. Vassallo, Jr.</p> <p>20 Thrombocytopenia and Platelet Transfusion</p> <p>Mike F. Murphy, Simon Stanworth, Lise Estcourt</p> <p>21 Management of Immune-Mediated Thrombocytopenia</p> <p>Donald M. Arnold, Ishac Nazi, James W. Smith, Theodore E. Warkentin</p> <p>Part III: White Blood Cells</p> <p>22  Neutrophil Production and Kinetics: Neutropenia and Neutrophilia</p> <p>Lawrence Rice and Miho Teruya</p> <p>23 Neutrophil Collection and Transfusion</p> <p>Ronald G. Strauss</p> <p>24 Leukocyte-Reduced Blood Components: Laboratory and Clinical Aspects</p> <p>Tor Hervig, Jerard Segatchian</p> <p>Part IV Plasma</p> <p>25 Composition of Plasma</p> <p>Peter Hellstern</p> <p>26 Plasma and Cryoprecipitate for Transfusion</p> <p>Simon J. Stanworth, Alan T. Tinmouth</p> <p>27 The Purification of Plasma Proteins for Therapeutic Use</p> <p>Joseph Bertolini</p> <p>28 Recombinant Products for the Treatment of Hemophilia: Recent Advances</p> <p>Michael Wilson, Andrew Nash, Iris Jacobs, Arna Andrews</p> <p>29 Coagulation Factor Concentrates for Inherited Bleeding Disorders</p> <p>Gary M. Woods, Amy L. Dunn</p> <p>30 Coagulation Factor Concentrates and Pharmacologic Therapies for Acquired Bleeding Disorders</p> <p>Neil Shah, Lawrence Tim Goodnough</p> <p>31  Immunoglobulin Products</p> <p>Melvin Berger</p> <p>Section III: Apheresis, Transplantation, and New Therapies</p> <p>32 Apheresis: Principles and Technology of Hemapheresis</p> <p>Edwin A. Burgstaler, Jeffrey L. Winters</p> <p>33 Therapeutic Apheresis</p> <p>Bruce McLeod, Shanna Morgan, Jeffrey McCullough</p> <p>34 Therapeutic Phlebotomy and Specialized Hemapheresis</p> <p>Jeffrey A. Bailey, Robert Weinstein</p> <p>35 Hematopoietic Growth Factors</p> <p>David J. Kuter</p> <p>36 Hematopoietic Stem Cells and Cord Blood</p> <p>Jeffrey McCullough</p> <p>37 Hematopoietic Stem Cell Transplantation</p> <p>Sameh Gaballa, Amin Alousi, Sergio Giralt, Richard Champlin</p> <p>38 Gene Therapy Applications to Transfusion Medicine</p> <p>Eric A. Gehrie, Alexey Bersenev, Emanuela Bruscia, Diane Krause, Wade Schulz</p> <p>39 HLA Antigens and Alleles</p> <p>Christian Naper, Bjarte G. Solheim</p> <p>40 Tissue Banking</p> <p>Ralph M. Powers, Jeanne V. Linden</p> <p>41 Adoptive Immunotherapy</p> <p>Sarah M. Drawz, Jeffrey S. Miller, David H. McKenna</p> <p>42 Tissue Engineering and Regenerative Medicine</p> <p>Sumati Sundaram, Joshua Siewert, Jenna Balestrini, Ashley Gard, Kevin Boehm, Elise Wilcox, Laura Niklason</p> <p>Section IV. Specialized Clinical Practice</p> <p>Part I: Obstetrics and Pediatrics</p> <p>43 Obstetric Transfusion Practice</p> <p>Marieke B.Veenhof, Jos J.M. van Roosmalen, Anneke Brand</p> <p>44 Fetal and Neonatal Hematopoiesis</p> <p>Robert D. Christensen, Martha C. Sola-Visner</p> <p>45 Hemolytic Disease of the Fetus and Newborn</p> <p>Bjarte G. Solheim, Morten Grönn, Thor Willy Ruud Hansen</p> <p>46 Red Blood Cell Transfusions for Neonates and Infants</p> <p>Ronald G. Strauss</p> <p>47 Platelet and Plasma Transfusions for Infants and Children</p> <p>Jeanne E. Hendrickson, Cassandra D. Josephson</p> <p>Part II: Surgery and Trauma</p> <p>48 Perioperative Transfusion Needs</p> <p>Leanne Clifford, Daryl J. Kor, James R. Stubbs</p> <p>49 Transfusion Therapy in the Care of Trauma and Burn Patients</p> <p>John R. Hess, John B. Holcomb, Steven E. Wolf, Michael W. Cripps<br /><br />Part III: Oncology</p> <p>50 Transfusion Support for the Oncology Patient</p> <p>Wade L. Schulz, Edward L. Snyder</p> <p>Section V. Hazards of Transfusion</p> <p>Part I: Infectious Hazards</p> <p>51 Transfusion Transmitted Virus Infections (TTVI)</p> <p>Erhard Seifried, Michael Schmidt</p> <p>52 Transfusion Transmission of Parasites</p> <p>Bryan R. Spencer</p> <p>53 Bacterial Contamination of Blood Components</p> <p>Richard J. Benjamin</p> <p>54 Prion Diseases</p> <p>Marc L. Turner</p> <p>55 Testing for Pathogens in Donors</p> <p>Tho D. Pham, Susan A. Galel</p> <p>56 Pathogen Reduction of Blood Components and Plasma Derivatives</p> <p>Nathan J. Roth</p> <p>Part II: Other Hazards</p> <p>57 Hemolytic Transfusion Reactions</p> <p>Robertson D. Davenport, Martin H. Bluth</p> <p>58 Febrile, Allergic, and Non-immune Transfusion Reactions</p> <p>Emmanuel Fadeyi, Gregory J. Pomper</p> <p>59 Transfusion-Related Lung Injury</p> <p>Ulrich J. Sachs, Jonathan P. Wallis</p> <p>60 Transfusion-Associated Graft Versus Host Disease</p> <p>Eric Gehrie, Edward Snyder, Alex Ryder</p> <p>61 Transfusional Iron Overload</p> <p>Sujit Sheth</p> <p>62  Immunomodulatory and Pro-Inlammatory Effects of Allogeneic Blood Transfusion</p> <p>Eleftherios C. Vamvakas, José O. Bordin, Morris A. Blajchman</p>

<p>The book has been substantially revised and updated, making it even more a patient-oriented publication with challenging contributions on advanced treatment modalities, including gene therapy, tissue engineering, and regenerative medicine.<br /><br />The book clearly demonstrates the current position of transfusion medicine, bridging the bedside with<br />the community.<br />Those experienced and interested in the field of transfusion medicine as well as those who want to explore the field are urged to use this comprehensive, patient-oriented book on the principles of transfusion medicine for the continued development and improvement of their practices, including the teaching and mentoring of students and learners. This jubilee edition brings the reader right in the middle of this exiting, but still young and rapidly expanding, field of health sciences ? transfusion medicine. <b>(International Journal of Clinical Transfusion Medicine review- November 2016)</b></p><p>"The book?s greatest strength is its section on apheresis, transplantation and new therapeutic methods, which introduces the reader to a number of areas at the frontier of medicine...It is still slanted towards the USA, but also has much to offer practitioners in transfusion medicine and clinicians with an interest in transfusion medicine in other countries." (<b>The Journal of the Norwegian Medical Association 24/02/2017<b>)

<p><b>Dr. Toby Simon</b> is senior medical director at CSL Behring, a biotherapeutics company that is a world leader in fractionation of plasma for blood derivatives. He has previous experience in both blood centers and transfusion services and did research in transfusion medicine for many years at the University of New Mexico School of Medicine and has most recently been a consultant to the NIH REDS II program. He is a past president of AABB and America’s Blood Centers. He served on the American Board of Pathology Transfusion Medicine Test Development and Advisory Committee for over 25 years and is currently in his second term as Inudstry Representative on the FDA Blood Products Advisory Committee.</p> <p><b>Dr. Jeffery McCullough</b> is professor of laboratory medicine and pathology at the University Of Minnesota School Of Medicine where he has been since 1978 including service as Medical Director of the hospital blood bank.. He directed the entire American Red Cross Blood Program in the past and has also served as President of the American Board of Pathology and several terms as editor of Transfusion. He has directed national research programs and published extensively including a single authored book in Transfusion Medicine published by Wiley.</p> <p><b>Dr. Edward Snyder</b> is professor of laboratory medicine at Yale University School of Medicine. He also serves as associate chair of his department for clinical affairs and director of apheresis/transfusion service and blood bank. He was an editor of the third and fourth editions of this text. He is a past-president of AABB. He has published extensively and is currently an investigator in the NIH REDS III project.</p> <p><b>Dr. Bjarte Solheim</b> is Professor Emeritus at the Institute of Immunology at Rikshospitalet University Hospital and University of Oslo School of Medicine in Oslo, Norway. He was an editor of the fourth edition and was instrumental in making this text an international one by recruiting many European authors. While officially retired, he remains active in clinical and research aspects of transfusion medicine.</p> <p><b>Dr. Ronald Strauss</b> is Professor Emeritus of Pathology and Pediatrics at the University Of Iowa School Of Medicine. Since his retirement from Iowa he has remained active in transfusion medicine research and has also been serving as associate medical director of LifeSource/Institute of Transfusion Medicine in Chicago. He serves on the American Board of Pathology Transfusion Medicine Test Development and Advisory Committee. He has a long research career with several NIH grants and roles in national research studies. He was an editor of the third and fourth editions.</p>

<p>Transfusion medicine as a multidisciplinary clinical specialty allied to blood banking continues to be a dynamic and increasingly complex evolution. Patients who require blood transfusions generally fall into two categories: those requiring transfusions resulting from acute blood loss that might be associated with surgery or accident; or those requiring chronic transfusions associated with treatment for chronic anaemias, chemotherapy, or bone marrow transplant. As such transfusion medicine impacts all areas of critical care medicine, and multiple areas of chronic care.</p> <p><i>Rossi's Principles of Transfusion Medicine</i> is the most comprehensive and practical reference on transfusion science and medicine available. Now updated for a fifth edition with new material on donor care – including the frequency of donation and management of iron deficiency/status, patient blood management, hemovigilance, and the novel cellular therapies and stem cell transplantation. This is a key resource for specialists and trainees in transfusion medicine and blood banking, as well as physicians, nurses, and medical technologists active in the transfusion of patients.</p> <p>This edition;</p> <ul> <li>Compiled by a world class Editor team including two past-presidents of AABB, a past- President of the American Board of Pathology and members of the FDA Blood Products Advisory Committee, and international contributor team</li> <li>Covers current hot topics such as donor care – including the frequency of donation and management of iron deficiency/status), patient blood management, hemovigilance, and the organization of transfusion and transplant services</li> <li>Presents new material on molecular immunohematology</li> <li>Companion website includes figures, full text and references</li> </ul> Update your practice with this comprehensive reference resource, considered the gold standard in transfusion medicine.

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