Details

Remote C-H Bond Functionalizations


Remote C-H Bond Functionalizations

Methods and Strategies in Organic Synthesis
1. Aufl.

von: Debabrata Maiti, Srimanta Guin

133,99 €

Verlag: Wiley-VCH
Format: EPUB
Veröffentl.: 11.01.2021
ISBN/EAN: 9783527824144
Sprache: englisch
Anzahl Seiten: 448

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Beschreibungen

<p><b>A guide to contemporary advancements in the field of distal C—H functionalization</b> <p><i>Remote C—H Bond Functionalizations</i> provides a comprehensive overview on the most recent developments in the field of distal C—H functionalization. The text explores how distal C—H functionalization can be applied in various pharmaceutical and agrochemical industries. With contributions from a noted panel of experts on the topic, the book offers a coherent and comprehensive discussion about different strategies. <p>The contributors cover a broad range of topics including C—H functionalization of palladium/norbornene catalysis, ruthenium-catalyzed remote functionalization, the non-directed distal C(sp<sub>2</sub>)—H, functionalization, transition metal catalyzed distal para-selective C—H functionalization, and much more. The book also includes information on effective strategies as well as the engineering of templates. Throughout the book, the authors lay the foundations for future research. This important book: <ul> <li>Contains the most recent research on one of the most important topics in organic synthesis</li> <li>Provides a broad overview on contemporary advancements in the field of distal C—H functionalization</li> <li>Includes deep insights into distal C—H functionalizations</li> <li>Offers information on applications in various industries</li> </ul> <p>Written for organic chemists, chemists working with organometallics, and industrial chemists, <i>Remote C—H Bond Functionalizations</i> presents a systematic compilation of the field.
Introduction<br> Transition Metal Catalyzed (Pd, Rh, Cu) Meta C-H Functionalization of Arenes by Directing Group Approach <br> Norbornene Mediated Distal C-H Functionalization of Haloarenes <br> Directing Group Assisted Meta C-H Functionalization by Catellani Reaction <br> Ruthenium Catalyzed Remote C-H Functionalization <br> Carboxylic Group as a Traceless Directing Group for Distal C(sp2)-H Functionalization <br> Harnessing Non-Covalent Interaction for Distal C(sp2)-H Functionalization by Ir and Pd<br> Non-Directed Distal C(sp2)-H Functionalization<br> Transition Metal Catalyzed Para C-H Functionalization of Arenes <br> Functionalization of Indoles and Related Heterocycles at Distal Positions (other than C2 and C3) <br> Mechanistic Perspective for Distal C(sp2)-H Activation <br> Directing Group Assisted Distal C(sp3)-H Functionalization of Acid, Amine, Ketone, Alcohol, and Thiol.<br> Radically Initiated Distal C(sp3)-H Functionalization <br> The Enzymatic Distal C(sp2)-H and C(sp3)-H Activation<br>
<p><b><i>Debabrata Maiti, PhD,</i></b><i> is Associate Professor in the Department of Chemistry at IIT Bombay.</i> <p><b><i>Srimanta Guin, PhD,</i></b><i> is National Post-doctoral Fellow at IIT Bombay.</i>
<p><b>A guide to contemporary advancements in the field of distal C—H functionalization</b> <p><i>Remote C—H Bond Functionalizations</i> provides a comprehensive overview on the most recent developments in the field of distal C—H functionalization. The text explores how distal C—H functionalization can be applied in various pharmaceutical and agrochemical industries. With contributions from a noted panel of experts on the topic, the book offers a coherent and comprehensive discussion about different strategies. <p>The contributors cover a broad range of topics including C—H functionalization of palladium/norbornene catalysis, ruthenium-catalyzed remote functionalization, the non-directed distal C(sp<sub>2</sub>)—H, functionalization, transition metal catalyzed distal para-selective C—H functionalization, and much more. The book also includes information on effective strategies as well as the engineering of templates. Throughout the book, the authors lay the foundations for future research. This important book: <ul> <li>Contains the most recent research on one of the most important topics in organic synthesis</li> <li>Provides a broad overview on contemporary advancements in the field of distal C—H functionalization</li> <li>Includes deep insights into distal C—H functionalizations</li> <li>Offers information on applications in various industries</li> </ul> <p>Written for organic chemists, chemists working with organometallics, and industrial chemists, <i>Remote C—H Bond Functionalizations</i> presents a systematic compilation of the field.

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