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Pulmonary Infection in the Immunocompromised Patient


Pulmonary Infection in the Immunocompromised Patient

Strategies for Management
1. Aufl.

von: Carlos Agusti, Antoni Torres

161,99 €

Verlag: Wiley
Format: PDF
Veröffentl.: 08.07.2009
ISBN/EAN: 9780470714188
Sprache: englisch
Anzahl Seiten: 456

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Beschreibungen

The immuno-compromised patient is more susceptible to a broader range of infections than others, and infections of the respiratory tract are among the first and most common to be encountered. <p>In this book the authors review current options for management for a group of patients that present unique challenges to the clinician, and for whom the choices of effective therapy are often limited.</p> <ul> <li>Most up to date book available dedicated specifically to this topic</li> <li>Major management issue in respiratory medicine for critical care, transplant and cancer patients</li> <li>Reviews important new advances in therapeutics, including drug resistance </li> </ul>
Foreword. <p>List of Contributors.</p> <p>Preface.</p> <p><b>1. Lung Immune Defences in the Immunosuppressed Patient (Naimish Patel and Henry Koziel).</b></p> <p>1.1 Introduction.</p> <p>1.2 Host defence function in health.</p> <p>1.3 Host defence function in select immunocompromised patients.</p> <p>1.4 Summary and future directions for this field.</p> <p><b>2. Microbiological Diagnosis of Respiratory Infections in the Immunocompromised (Margareta Ieven).</b></p> <p>2.1 Introduction.</p> <p>2.2 HIV infection and Mycobacterium tuberculosis.</p> <p>2.3 HIV infection and Non Tuberculous Mycobacteria.</p> <p>2.4 HIV and Pneumocystis jirovecii.</p> <p>2.5 Infections in transplant patients or other immunodeficiencies.</p> <p>2.6 Concluding remarks.</p> <p><b>3. Diagnosis of Pneumonia in Immunocompromised Patients (Robert P. Baughman and Elyse E. Lower).</b></p> <p>3.1 Introduction.</p> <p>3.2 Clinical assessment.</p> <p>3.3 Blood cultures.</p> <p>3.4 Sputum.</p> <p>3.5 Endotracheal aspirate.</p> <p>3.6 Non bronchoscopic bronchoalveolar lavage.</p> <p>3.7 Protected brush sample (PBS).</p> <p>3.8 Bronchoalveolar lavage (BAL).</p> <p>3.9 Transbronchial biopsy (TBB).</p> <p>3.10 Surgical lung biopsy (SLB).</p> <p>3.11 Sample processing.</p> <p>3.12 Clinical approach to pulmonary infiltrates in immunosuppressed patient.</p> <p>3.13 Conclusion.</p> <p><b>4. Pulmonary Imaging in Immunocompromised Patients (Tom s Franquet).</b></p> <p>4.1 Pulmonary infections in immunocompromised patients.</p> <p>4.2 Respiratory infections.</p> <p>4.3 Interventional procedures in patients with pneumonia.</p> <p>4.4 Summary.</p> <p><b>5. Pulmonary Infections in HIV Patients in the Highly Active Antiretroviral Therapy Era (Natividad Benito and Asunci¢n Moreno-Camacho).</b></p> <p>5.1 Introduction.</p> <p>5.2 Epidemology and etiology.</p> <p>5.3 Diagnosis.</p> <p>5.4 Prognosis.</p> <p>5.5 Conclusions.</p> <p><b>6. Neutropenia (Maria J. Rping, J"rg J. Vehreschild, Santiago Ewig, and Oliver A. Cornely).</b></p> <p>6.1 Introduction.</p> <p>6.2 Management of the neutropenic patient.</p> <p>6.3 Specific infectious diseases.</p> <p><b>7. General Management of Suspected Pneumonia in the Solid Organ Transplant Paitent (Andrew F. Shorr).</b></p> <p>7.1 Introduction.</p> <p>7.2 Epidemiology.</p> <p>7.3 Differential diagnosis and non-infectious complications.</p> <p>7.4 Diagnostic approach.</p> <p>7.5 Conclusion.</p> <p><b>8. Respiratory Infections Following Haematopoietic Stem Cell Transplantation (Ayman O. Soubani).</b></p> <p>8.1 Immune system recovery after HSCT.</p> <p>8.2 Bacterial pneumonia.</p> <p>8.3 Invasive pulmonary aspergillosis.</p> <p>8.4 Cytomegalovirus.</p> <p>8.5 Community respiratory viruses.</p> <p>8.6 Non-infectious pulmonary complications.</p> <p>8.7 Conclusion.</p> <p><b>9. Chronic Non-infectious Pulmonary Complications in Haematopoietic Stem Cell Transplantation (Bekele Afessa and Steve G. Peters).</b></p> <p>9.1 Introduction.</p> <p>9.2 Bronchiolitis Obliterans (BO).</p> <p>9.3 Bronchiolitis Obliterans organizing pneumonia (BOOP).</p> <p>9.4 Idiopathic pneumonia syndrome (IPS).</p> <p>9.5 Diffuse alveolar haemorrhage (DAH).</p> <p>9.6 Peri-engraftment respiratory distress syndrome (PERDS).</p> <p>9.7 Delayed pulmonary toxicity syndrome (DPTS).</p> <p>9.8 Pulmonary cytolytic thrombi (PCT).</p> <p>9.9 Other non-infectious pulmonary complications.</p> <p>9.10 Summary.</p> <p><b>10. Pulmonary Infections in Patients on Chronic Glucocorticoid Treatment (Ana Ra¤¢ and Carlos Agust¡).</b></p> <p>10.1 Introduction.</p> <p>10.2 Associated inflammatory response in pneumonia.</p> <p>10.3 Glucocorticoids: mechanisms of action.</p> <p>10.4 Glucocorticoid therapy in clinical practice.</p> <p>10.5 Diagnostic approach.</p> <p>10.6 Empirical treatment of suspected pneumonia in patients receiving chronic GC therapy.</p> <p>10.7 Prognosis.</p> <p>10.8 Conclusions.</p> <p><b>11. Intensive Care Management in the Immunocompromised Patient with Pulmonary Infiltrates (Gilles Hilbert, Didier Gruson, and Frederic Vargas).</b></p> <p>11.1 Introduction.</p> <p>11.2 Invasive ventilation.</p> <p>11.3 Rationale for NIV.</p> <p>11.4 Mechanisms of improvement with NIV in immunocompromised patients with acute respiratory failure.</p> <p>11.5 Clinical studies.</p> <p>11.6 Equipment and techniques: particularities in immunocompromised patients.</p> <p>11.7 Predictive factors of NIV outcome.</p> <p>11.8 Conclusions.</p> <p><b>12. Current Strategies and Future Directions in Antibacterial Treatment (Jan Jelrik Oosterheert and Andy I.M. Hoepelman).</b></p> <p>12.1 Introduction.</p> <p>12.2 Farmacokinetics and farmacodynamics.</p> <p>12.3 Antibacterial treatment options.</p> <p>12.4 Resistance.</p> <p>12.5 HIV related bacterial pulmonary infections.</p> <p>12.6 Length of treatment.</p> <p>12.7 Conclusions.</p> <p><b>13. Current Strategies in the Treatment of Fungal Infections in the Intensive Care Unit Setting (Mitchell Goldman and George A. Sarosi).</b></p> <p>13.1 Introduction.</p> <p>13.2 Antifungal therapies.</p> <p>13.3 The endemic fungi in the critical care unit.</p> <p>13.4 Other yeast infections in the critical care unit.</p> <p>13.5 Invasive mould infections in the critical care unit.</p> <p>13.6 Summary.</p> <p><b>14. Current Strategies and Future Directions in Cytomegalovirus (CMV) Pneumonitis (Julio C. Medina and Jos‚ M. Aguado).</b></p> <p>14.1 Effects of CMV infection in immunocompromised patients.</p> <p>14.2 Pathophysiology of CMV pneumonitis.</p> <p>14.3 Risk factors for CMV pneumonitis.</p> <p>14.4 Pulmonary manifestations of CMV infection.</p> <p>14.5 Indirect respiratory effects of CMV infection.</p> <p>14.6 Diagnosis of CMV pneumonitis.</p> <p>14.7 Antiviral agents against CMV.</p> <p>14.8 Treatment of CMV pneumonia.</p> <p>14.9 Prevention of CMV pneumonia.</p> <p><b>15. Antiviral Agents against Respiratory Viruses (Michael G. Ison).</b></p> <p>15.1 M2 inhibitors.</p> <p>15.2 Neuraminidase inhibitors.</p> <p>15.3 Cidofovir.</p> <p>15.4 Ribavirin.</p> <p>15.5 Investigational agents.</p> <p>Index.</p>
<p>Carlos Agusti and Antoni Torres are the authors of Pulmonary Infection in the Immunocompromised Patient: Strategies for Management, published by Wiley.

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