We dedicate this book to all people living with diabetes and the healthcare professionals who look after them. We would also like to dedicate this book to our families without whose support and encouragement the book would never have been finished.
This edition first published 2017 © 2017 by John Wiley & Sons Ltd
Previous editions: 1991, 1997, 2003, 2010
Registered office: John Wiley & Sons, Ltd, The Atrium, Southern Gate, Chichester, West Sussex,
PO19 8SQ, UK
Editorial offices: 9600 Garsington Road, Oxford, OX4 2DQ, UK
The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK
111 River Street, Hoboken, NJ 07030-5774, USA
For details of our global editorial offices, for customer services and for information about how to apply for permission to reuse the copyright material in this book please see our website at www.wiley.com/wiley-blackwell
The right of the author to be identified as the author of this work has been asserted in accordance with the UK Copyright, Designs and Patents Act 1988.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher.
Designations used by companies to distinguish their products are often claimed as trademarks. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks of their respective owners. The publisher is not associated with any product or vendor mentioned in this book. It is sold on the understanding that the publisher is not engaged in rendering professional services. If professional advice or other expert assistance is required, the services of a competent professional should be sought.
The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting a specific method, diagnosis, or treatment by health science practitioners for any particular patient. The publisher and the author make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of fitness for a particular purpose. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. Readers should consult with a specialist where appropriate. The fact that an organization or Website is referred to in this work as a citation and/or a potential source of further information does not mean that the author or the publisher endorses the information the organization or Website may provide or recommendations it may make. Further, readers should be aware that Internet Websites listed in this work may have changed or disappeared between when this work was written and when it is read. No warranty may be created or extended by any promotional statements for this work. Neither the publisher nor the author shall be liable for any damages arising herefrom.
Library of Congress Cataloging-in-Publication Data
Names: Holt, Richard I. G., editor. | Cockram, Clive S., editor. | Flyvbjerg,
Allan, editor. | Goldstein, Barry J., editor.
Title: Textbook of diabetes / edited by Richard I.G. Holt, Clive S. Cockram,
Allan Flyvbjerg, Barry J. Goldstein.
Other titles: Textbook of diabetes (Pickup)
Description: Fifth edition. | Chichester, West Sussex, UK; Hoboken, NJ :
Wiley-Blackwell, 2016. | Preceded by Textbook of diabetes / edited by
Richard I.G. Holt … [et al.]. 4th ed. 2010. | Includes bibliographical
references and index.
Identifiers: LCCN 2016014428| ISBN 9781118912027 (cloth) | ISBN 9781118924860
(epub) | ISBN 9781118924877 (Adobe PDF)
Subjects: | MESH: Diabetes Mellitus
Classification: LCC RC660 | NLM WK 810 | DDC 616.4/62–dc23 LC record available at https://lccn.loc.gov/2016014428
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.
Cover images: Left inset: Gettyimages/AndreyPopov; Right inset: Gettyimages/SCIEPRO