Edited by
This edition first published 2019
© 2019 John Wiley & Sons Ltd
Registered office
John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, United Kingdom
For details of our global editorial offices, for customer services and for information about how to apply for permission to reuse the copyright material in this book please see our website at www.wiley.com.
The right of A. C. Knipe to be identified as the editor of this work has been asserted in accordance with the Copyright, Designs and Patents Act 1988.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.
Designations used by companies to distinguish their products are often claimed as trademarks. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks of their respective owners. The publisher is not associated with any product or vendor mentioned in this book.
Limit of Liability/Disclaimer of Warranty: While the publisher and editor have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. It is sold on the understanding that the publisher is not engaged in rendering professional services and neither the publisher nor the editor shall be liable for damages arising herefrom. If professional advice or other expert assistance is required, the services of a competent professional should be sought.
The advice and strategies contained herein may not be suitable for every situation. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of experimental reagents, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each chemical, piece of equipment, reagent, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. The fact that an organization or Website is referred to in this work as a citation and/or a potential source of further information does not mean that the editor or the publisher endorses the information the organization or Website may provide or recommendations it may make. Further, readers should be aware that Internet Websites listed in this work may have changed or disappeared between when this work was written and when it is read. No warranty may be created or extended by any promotional statements for this work. Neither the publisher nor the editor shall be liable for any damages arising herefrom.
Library of Congress Catalog Card Number 66-23143
British Library Cataloging in Publication Data
A catalogue record for this book is available from the British Library
Print ISBN: 978-1-119-12498-6
C. T. BEDFORD | Department of Chemistry, University College London, 20 Gordon Street, London, WC1H 0AJ, UK |
M. L. BIRSA | Faculty of Chemistry, ‘Al. I. Cuza’ University of Iasi, Bd. Carol I, 11, Iasi 700506, Romania |
S. CHASSAING | Laboratoire de Synthèse, Réactivité Organiques et Catalyse, Institut de Chimie, CNRS‐UMR7177, Université de Strasbourg, 1 rue Blaise PASCAL, 67000 Strasbourg, France |
J. M. COXON | Department of Chemistry, University of Canterbury, Christchurch, New Zealand |
M. R. CRAMPTON | Department of Chemistry, University of Durham, Durham, DH1 3LE, UK |
N. DENNIS | 3 Camphor Laurel Crt, Stretton, Brisbane, Queensland 4116, Australia |
E. GRAS | Laboratoire de Chimie de Coordination, Centre National de la Recherche Scientifique, Université Fédérale de Toulouse Midi-Pyrénées, Toulouse, France |
D. A. KLUMPP | Department of Chemistry, Northern Illinois University, DeKalb, IL 60115, USA |
A. C. KNIPE | School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland |
R. N. MEHROTRA | Formerly of Department of Chemistry, Jai Narain Vyas University, Jodhpur 342005, India |
B. A. MURRAY | Department of Science, Institute of Technology, Tallaght (ITT Dublin), Dublin D24 FKT9, Ireland |
K. C. WESTAWAY | Department of Chemistry and Biochemistry, Laurentian University, Sudbury, Ontario P3E 2C6, Canada |
The present volume, the 51st in the series, surveys research on organic reaction mechanisms described in the available literature dated 2015. In order to limit the size of the volume, it is necessary to exclude or restrict overlap with other publications which review specialist areas (e.g. photochemical reactions, biosynthesis, enzymology, electrochemistry, organometallic chemistry, surface chemistry, and heterogeneous catalysis). In order to minimize duplication, while ensuring a comprehensive coverage, the editor conducts a survey of all relevant literature and allocates publications to appropriate chapters. While a particular reference may be allocated to more than one chapter, it is assumed that readers will be aware of the alternative chapters to which a borderline topic of interest may have been preferentially assigned.
All the chapters have been written by the members of a team of experienced ORM contributors who have submitted authoritative reviews over many years. We are naturally pleased to benefit from such commitment and consequent awareness of developing trends in the title area. Particularly noteworthy in recent years has been a major impact on directed organic synthesis through mechanistic studies which enable optimization of ligand design for highly selective transition metal catalysts.
In view of the considerable interest in the application of stereoselective reactions to organic synthesis, we now provide indication, in the margin, of reactions which occur with significant diastereomeric or enantiomeric excess (de or ee).
Although every effort was made to reduce the delay between the title year and the publication date, circumstances beyond the editor's control again resulted in the late arrival of a substantial chapter which made it impossible to regain our optimum production schedule. Steps have been taken to reduce the knock‐on effect of this occurrence.
I wish to thank the staff of John Wiley & Sons and our expert contributors for their efforts to ensure that the review standards of this series are sustained.
A. C. K.