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<p>Foreword xi<br /> Guy FRIJA</p> <p><b>Chapter 1. Interactions between Radiation and Matter: Consequences for Detection and Medical Imaging 1</b><br /> Jean-Pierre MOY</p> <p>1.1. The limits of imaging using light 1</p> <p>1.2. Imaging with other types of radiation 2</p> <p>1.3. X-rays: their interaction with matter 3</p> <p>1.4. Radiological imaging relies on the X-ray-matter interaction 19</p> <p>1.5. Consequences of interaction modes on detection 22</p> <p>1.6. Conclusion 33</p> <p>1.7. Bibliography 33</p> <p><b>Chapter 2. Detectors for Medical Imaging 35</b><br /> Hervé FANET</p> <p>2.1. Radiation-matter interaction and signal formation 36</p> <p>2.2. Flux, energy, time and position measurements 64</p> <p>2.3. Semi-conductor detectors 86</p> <p>2.4. Scintillation and measurement channel 102</p> <p>2.5. Pixel detectors 116</p> <p>2.6. Bibliography 121</p> <p><b>Chapter 3. Quantitative Digital Radiography Image Processing 123</b><br /> Jean RINKEL and Jean-Marc DINTEN</p> <p>3.1. Introduction to flat-panel sensors 123</p> <p>3.2. Relation between physical quantities and radiographic acquisition 129</p> <p>3.3. Access to linear attenuation coefficients from the attenuation image 133</p> <p>3.4. Access to physical dimensions by combining several X-rays of a flat sensor 149</p> <p>3.5. Conclusion 158</p> <p>3.6. Bibliography 159</p> <p><b>Chapter 4. X-Ray Tomography 161</b><br /> Françoise PEYRIN and Philippe DOUEK</p> <p>4.1. Introduction 161</p> <p>4.2. Principle of the first acquisition systems 162</p> <p>4.3. Physical aspects and the direct problem 165</p> <p>4.4. Principle of tomographic image reconstruction 169</p> <p>4.5. Evolution of X-ray scanners and reconstruction algorithms 181</p> <p>4.6. Examples of clinical applications 189</p> <p>4.7. From tomography to micro-tomography 198</p> <p>4.8. Conclusion 200</p> <p>4.9. Bibliography 201</p> <p><b>Chapter 5. Positron-Emission Tomography: Principles and Applications 207</b><br /> Régine TRÉBOSSEN</p> <p>5.1. Introduction 208</p> <p>5.2. PET: principle and performance 210</p> <p>5.3. PET systems 218</p> <p>5.4. PET for cancer staging 223</p> <p>5.5. Conclusion 225</p> <p>5.6. Bibliography 226</p> <p><b>Chapter 6. Single Photon Imaging 229</b><br /> Irène BUVAT</p> <p>6.1. Introduction 229</p> <p>6.2. Overview of single photon imaging 230</p> <p>6.3. Conventional detection systems in single photon imaging: the scintillation gamma camera 233</p> <p>6.4. Innovative systems: semiconductor detectors 240</p> <p>6.5. Tomographic reconstruction and corrections 241</p> <p>6.6. Hybrid detectors 258</p> <p>6.7. Applications 259</p> <p>6.8. Future developments 261</p> <p>6.9. Conclusion 262</p> <p>6.10. Bibliography 262</p> <p><b>Chapter 7. Optical Imaging 267</b><br /> Anabela DA SILVA</p> <p>7.1. Introduction 267</p> <p>7.2. Physics of luminous propagation in biological tissue 268</p> <p>7.3. Different optical imaging techniques for different applications 289</p> <p>7.4. Conclusion 312</p> <p>7.5. Bibliography 313</p> <p>List of Authors 325</p> <p>Index 327</p>

<b>Hervé Fanet</b>, Research engineer at CEA Leti. He is in charge of scientific cooperation and training activities within the MINATEC (micro and nanotechnology) in Grenoble.

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