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<p>Preface xxv</p> <p><b>Part I: Phytopharmaceuticals in Various Diseases 1</b></p> <p>1 Ayurvedic Approaches to Oral Health and Hygiene: A Review 3<br /><i>Manindra Mohan Shrivastava, Prashant Kr. Gupta, Kamal Shah, Durgesh Nandini Chauhan and Nagendra Singh Chauhan</i></p> <p>2 Emerging Role of Medicinal Plants in the Prevention of Oral Cavity Disorders 33<br /><i>Navneet Kishore and Bhanu Pratap Singh</i></p> <p>3 Natural Oral Care and Herbal Products for Oral Diseases and Oral Hygiene Maintenance 47<br /><i>Goma Kathayat, Diane Isabel Selvido, Hans Erling Skallevold, Maan Bahadur Rokaya, Bishwa Prakash Bhattarai, Anand Marya and Dinesh Rokaya</i></p> <p>4 Complementary and Alternative Medicine: Gains and Drawbacks with Special Reference to Oral Healthcare 61<br /><i>Ezi Abigail Akaji</i></p> <p>5 Nutraceutical Agents on Oral and Periodontal Health and Disease 83<br /><i>Gaetano Isola, Alessandro Polizzi and Simona Santonocito</i></p> <p>6 Role of Herbal Products as Denture Disinfectants and Cleansers 103<br />Jacob Mathew Philip, Helen Mary Abraham, Tamizhesai, M. Navin Bharathy, C.J. Venkatakrishnan, Saranya Varadarajan, Raghunathan Jagannathan and Thodur Madapusi Balaji</p> <p>7 Use of Natural Oral Care Products in Orthodontics 125<br /><i>Anand Marya, Mohmed Isaqali Karobari, Pravin Kumar Shah and Dinesh Rokaya</i></p> <p>8 Herbs and Their Applications as Root Canal Medicaments 149<br /><i>S. Balagopal, Vandana James, Nagarajan Geethapriya, Shekar Shobana, Saranya Varadarajan, Raghunathan Jagannathan and Thodur Madapusi Balaji</i></p> <p>9 Herb-Derived Phytochemicals for Dental Implant Applications 167<br /><i>Saranya Varadarajan, Narasimman Muthusamy, Nithiyarajan Nambirajan, Rathinavel Pandian Manickavel, C.J. Venkatakrishnan, Jimson Samson, Raghunathan Jagannathan, Thodur Madapusi Balaji, S. Lakshmi Priya and Swaminathan Rajendran</i></p> <p>10 Natural Compounds in the Treatment of Oral Submucous Fibrosis 183<br /><i>Urmi Ghone, Gargi Sarode and Sachin Sarode</i></p> <p>11 The Effects of Natural Products on Mouth Sores 197<br /><i>Marzie Boskabady, Sepide Behrouz, Mahla Mohammadi and Mohammad Hossein Boskabady</i></p> <p>12 Natural Products to Cure Bad Breath 217<br /><i>Khalid Mohammed Khan, Shehryar Hameed and Shahbaz Shamim</i></p> <p>13 Herbal Formulations as Denture Cleansers 253<br /><i>Amar Bhochhibhoya, Sahara Shrestha, Rejina Shrestha and Manjeev Guragain</i></p> <p>14 Natural Oral Care Therapy for Peri-Implant Diseases 269<br /><i>Bharat Mirchandani, Hans Erling Skallevold, Artak Heboyan, Diane Isabel Selvido, Viritpon Srimaneepong, Pasutha Thunyakitpisa and Dinesh Rokaya</i></p> <p>15 Natural Compounds in the Treatment of Recurrent Aphthous Stomatitis 285<br /><i>Gargi Sarode, Madhura Pawar, Vivek Pawar and Sachin Sarode</i></p> <p>16 Alveolar Bone Protective Effects of Natural Products 299<br /><i>Diane Isabel Selvido, Hans Erling Skallevold, Bishwa Prakash Bhattarai, Rajesh Dashaputra, Azeem UI Yaqin Syed and Dinesh Rokaya</i></p> <p>17 Natural Oral Care Products for the Treatment of Stomatitis 311<br /><i>Vivekanand Kattimani, Gnana Sarita Kumari Panga, Swetha Gnanavel, Deepeka Saravanan and Nagalaxmi Hymavathi Chintalapati</i></p> <p><b>Part II: Plants and Phytoconstituents Used in Natural Oral Care 357</b></p> <p>18 Cranberry and Oral Health 359<br /><i>Kamal Shigli, Sushma S. Nayak, U. B. Bolmal and Kamal Shah</i></p> <p>19 Mangroves: Potent Botanicals as Therapeutics for Oral Ailments 391<br /><i>Merry Kashyap, Akshar Radhakrishnan, Priyanka Singh, Amrita Sinharay, Kavyasree Marabanahalli Yogendraiah and Santosh Anand</i></p> <p>20 Tea Tree Oil on Oral Health -- A Systematic Review 403<br /><i>Kalyana Chakravarthy Pentapati and Chenna Deepika</i></p> <p>21 Oregano Oil and Grape Seed Oil -- A Potent Displacer of Commercially Available Denture Cleansers 425<br /><i>Shetty Prajna P., Chowdhary Ramesh, Shetty Pooja P. and Volety Supraja</i></p> <p>22 Punica granatum (Pomegranate): A Potential Herbal Medicine in Treating Periodontal Disease in the Modern World of Dentistry 435<br /><i>Sumanth Gunupati, Sukrutha Biradavolu, Priyanka Nitin and Thummala Kalyani</i></p> <p>23 Potential Effects of Schinus terebinthifolia Raddi (Anacardiaceae) for the Treatment of Oral Conditions 453<br /><i>Ana Carolina Rivas, Nathalya Maria Vilela Moura and Mario Taba Jr.</i></p> <p>24 Melatonin: A Naturally Derived Molecule as a Protector of Oral Health 467<br /><i>Thodur Madapusi Balaji, Saranya Varadarajan, C.J. Venkatakrishnan, Raghunathan Jagannathan, Bhuvaneswari Birla Bose, Juala Catherine, Vignesh Vikram, T. Parthasarathi, S. Lakshmi Priya and Swaminathan Rajendran</i></p> <p>25 Myrrha and Oral Health 485<br /><i>Randa A. Alfotawi</i></p> <p>26 Syzygium aromaticum -- Role in Oral Health and Dental Care 499<br /><i>Vahid Reza Askari, Zohre Najafi and Vafa Baradaran Rahimi</i></p> <p>27 Acemannan: A Promising Natural Polysaccharide in Dentistry 519<br /><i>Hans Erling Skallevold, Dinesh Rokaya and Pasutha Thunyakitpisal</i></p> <p>28 Piper betel Linn. (Betel Leaf) and Its Beneficial Effects in Orodental Ailments: A Memoir 539<br /><i>Aditya Shetty, Princy Louis Palatty, Bharathi Shetty, Sembagalakshmi Thirunarayanan, Priyanka Latha Senthilkumar, Sharake Meera, Suresh Rao, Shamprasad Varija Raghu and Manjeshwar Shrinath Baliga</i></p> <p>29 Aloe Vera and Oral Health: A Systematic Review 553<br /><i>Kalyana Chakravarthy Pentapati, Hanan Siddiq and Abhinav T.N.</i></p> <p>30 Cinnamomum zeylanicum -- A Review for Its Role in Oral Health and Dental Care 577<br /><i>Vahid Reza Askari, Zohre Najafi and Vafa Baradaran Rahimi</i></p> <p>31 Babool (Acacia nilotica) and Oral Health 597<br /><i>Anupam Jaiswal, Megha Verma, Seema Kohli, Durgesh Nandini Chauhan, Kamal Shah and Nagendra Singh Chauhan</i></p> <p>32 Applications of Andrographis paniculata and Its Constituents for Management of Oral Diseases 607<br /><i>Ambili R., Nisha K.J., Biji Brigit K. and Rema J.</i></p> <p><b>Part III: Advancement in Natural Product Oral Care 629</b></p> <p>33 In Silico Approach with Phytochemical Analysis and Its Role in Oral Potentially Malignant Disorders (OPMD) and Oral Cancer 631<br /><i>Vaibhav Sunil Ladke, Gitanjali Javir and Gauri M. Kumbhar</i></p> <p>34 Anticancer Activities of Trigonella foenum-graecum L. and Trigonelline on an Oral Squamous Cell Carcinoma Cell Line 641<br /><i>Saranya Varadarajan, Thodur Madapusi Balaji, Malathi Narasimhan, Durai Pandian Chamundeeswari Meenakshi and Dhanapal Sakthisekaran</i></p> <p>35 Evaluation of The Anti-Inflammatory Action of Andiroba Oil -- Carapa guianensis aubl (Meliceae) in Oral Mucositis 651<br /><i>Fabricio Mesquita Tuji, Priscilla Bittencourt de Almeida Figueiredo, Gabriel Henrique Soares Cavalcante and Rommel Mario Rodriguez Burbano</i></p> <p>36 Trends of Clinical Studies with Xylitol or Propolis Toothpastes 669<br /><i>Mariana Leonel Martins, Natália Magno Von Helde, Yuri Wanderley Cavalcanti, Lucianne Cople Maia and Andréa Fonseca-Gonçalves</i></p> <p>37 Use of Polyols in Dentistry: Effects on Tooth Mineral Dynamics and Oral Biofilms 689<br /><i>Igor Zen, Tamires Passadori Martins, Caio Sampaio, Alberto Carlos Botazzo Delbem, Douglas Roberto Monteiro and Juliano Pelim Pessan</i></p> <p>38 Therapeutic Activity of Salvia officinalis L. Hydro-Ethanolic Extract from Aerial Parts on Dental Disease 703<br /><i>Maryam Eidi and Reza Ghahramani</i></p> <p>39 Effect of Black Pomegranate Hydro-Ethanolic Extract from Peel in Diabetic Male Rats with Candida albicans Oral Mucosa Infection 713<br /><i>Maryam Eidi and Reza Ghahramani</i></p> <p>40 In Vitro and In Vivo Efficacy of Phytoactive-Based Oral Care Regimens in the Prophylaxis of Oral Biofilm and Augmentation of Oral Hygiene 723<br /><i>Arumugam Priya, Nagaiah Hari Prasath, Nambiraman Malligarjunan and Shunmugiah Karutha Pandian</i></p> <p>41 Natural Oral Care Approach and Application in COVID-19 Management 775<br /><i>Beuy Joob and Viroj Wiwanitkit</i></p> <p>42 Fabricated Plant-Based Nanoformulations: Therapeutics for Oral Health 793<br /><i>Santosh Anand and Prabhakar Mishra</i></p> <p>Index 807</p>

<p><b>Durgesh Nandini Chauhan</b> completed her M.Pharma in pharmaceutics from Uttar Pradesh at the Dr. A.P.J. Abdul Kalam Technical University, Lucknow in 2006. She is currently working as an assistant professor in the Columbia Institute of Pharmacy, Raipur, Chhattisgarh, India. She has written more than 100 articles in national and international journals, 15 book chapters, and edited 4 books including <i>Natural Oral Care in Dental Therapy</i> (Wiley-Scrivener 2020). <p><b>Prabhu Raj Singh</b> obtained his Master of Dental Surgery in Prosthodontics from Sardar Patel Post Graduate Institute of Dental and Medical Science, Lucknow in 2017. He is working for the Sinhgad Education Society as an Assistant Professor in the Department of Prosthodontics. <p><b>Nagendra Singh Chauhan</b> obtained his M.Pharm, PhD from the Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar in 2006 and 2011 respectively. He is currently working as a senior scientific officer and government analyst at the Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh, India. He has professional expertise in natural product isolation and phytopharmacology. He has written more than 50 articles published in national and international journals, 22 book chapters, and edited one book. <p><b>Kamal Shah</b> has more than 14 years of research and teaching experience and currently is an associate professor at the Institute of Pharmaceutical Research, GLA University, Mathura, India. He completed his B. Pharma from Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal (M.P.) in 2003. He was a gold medalist in B.Pharm, M.Pharm. from the Department of Pharmaceutical Sciences, Sagar University, Sagar, India and has a PhD from APJ Kalam University Lucknow, India. He has written more than 30 articles in national and international journals, 6 book chapters and co-edited <i>Natural Oral Care in Dental Therapy</i> (Wiley-Scrivener 2020).

<p><b>Edited by a natural product scientist, clinician, pharmacologist and a dental surgeon, the book helps oral care specialists to implement safe and effective natural medicine therapies to complement current practice guidelines.</b></p> <p>With oral care specialists focusing their attention on the interdisciplinary connections between oral health, heart health, gastrointestinal health, etc., and with increasing antibiotic resistance and stronger antibiotics now reserved for serious active infection, the importance of herbal antibiotics is increasing exponentially. This book helps to implement safe and effective natural medicine therapies to complement the current practice guidelines. <p><i>Pharmacological Studies in Natural Oral Care</i> is a comprehensive compilation and explores all the measures to utilize the natural oral care obtained from plants, animals, and mineral drugs for dental care. Herbal extracts are used in dentistry for reducing inflammation, as antimicrobial plaque agents, for preventing the release of histamine, and as antiseptics, antioxidants, antimicrobials, antifungals, antibacterials, antivirals and analgesics. They also aid in healing and are effective in controlling microbial plaque in gingivitis and periodontitis, thereby improving immunity. <p><b>Audience</b> <p>This important new book will be invaluable to medicinal chemists, pharmacologists, natural product formulation scientists, dental surgeons, orthodontists, periodontists, endodontists, prosthodontists, maxillofacial surgeons, dentists, oral hygienists, as well as a reference for the pharmaceutical/ herbal industries and dental libraries.

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