Details

Pharmaceutical Systems

Global Perspectives
1. Aufl.

von: John Lilja, Sam Salek, Aldo Alvarez, David Hamilton
61,99 €
Verlag:	Wiley
Format:	PDF
Veröffentl.:	27.05.2008
ISBN/EAN:	9780470754047
Sprache:	englisch
Anzahl Seiten:	356

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Beschreibungen

Titelbeschreibung

<ul> <li>Offers a social view of the activities leading to the timely patient access to medicines including: drug research, drug production, drug distribution, drug prescribing, drug information and drug control</li> <li>Provides theoretical models to enable pharmacists to understand the organization of drug systems in their particular global territory</li> <li>Written specifically with the needs of pharmacy students taking Master's degrees in mind</li> </ul>

Inhaltsverzeichnis

Preface ix About the authors xi 1 Introduction 1 1.1 Economic development 1 1.2 Systems analysis 3 1.3 Actors in the pharmaceutical systems 8 1.4 Evaluations 17 1.5 Data collection 20 1.6 Summary of results and formulation of conclusions 20 1.7 Social constructionism and social representation theory 21 1.8 The actor–spectator paradox 25 1.9 Decision-making processes in the drug system 26 1.10 How attitudes and beliefs change – the balance model 29 1.11 Summary 32 References 33 2 A historical perspective of drug research and diffusion 39 2.1 The period of folk medicine 39 2.2 The merchant period (1500 AD to the end of the eighteenth century) 39 2.3 The chemical period (the nineteenth century) 44 2.4 The animal testing period (from 1900 to the end of the 1930s) 47 2.5 The drug innovation period (from 1940 to 1964) 49 2.6 The post-Thalidomide period (1965 to present) 51 2.7 Future perspectives 56 2.8 Summary 56 References 57 3 National drug policies 61 3.1 Efficient organization of drug support 62 3.2 Efficient organization of drug research 63 3.3 Efficient organization of drug production 65 3.4 Efficient organization of drug distribution 66 3.5 An efficient system for drug consumption 68 3.6 A satisfactory system of drug information 69 3.7 Choice of drugs with high therapeutic powers 70 3.8 Choice of drugs with few side effects 75 3.9 Low drug costs 77 3.10 How to develop and implement a national policy 77 3.11 Summary 78 References 78 4 Planning the drug support 81 4.1 Patent and exclusivity policies 81 4.2 Trade name policy vs. generic name policy 84 4.3 Generic and therapeutic substitution 85 4.4 Generic prescribing 87 4.5 Drug registration 88 4.6 Drug reimbursement policies/national health insurance systems 90 4.7 The public and private drug sectors of developing countries 93 4.8 The primary health care policy 95 4.9 The essential drugs (ED) policy 99 4.10 Summary 102 References 103 5 Drug research 109 5.1 Drug company strategies 110 5.2 Factors which determine the resources a drug company spends on R&D 112 5.3 The selection of research areas by a drug company 115 5.4 The research process 116 5.5 The project decision 118 5.6 The research administration after a project has been accepted 120 5.7 Research productivity 122 5.8 Ethical concerns in drug research 124 5.9 Summary 125 References 126 6 Drug production 129 6.1 Background 129 6.2 Variations between countries 133 6.3 The decision regarding which drug(s) to produce 134 6.4 The organization of production lines 139 6.5 Production of drug raw materials 141 6.6 Drug quality 142 6.7 Principles of technical assistance support 144 6.8 The decision where to locate the plant 145 6.9 Determination of production quantities 146 6.10 Export decisions 146 6.11 Summary 147 References 148 7 Drug prices, cost controls and profits in the drug industry 151 7.1 Price setting of raw drug materials 151 7.2 Price setting of ready-made drugs 154 7.3 Price setting of patented drugs 156 7.4 Price setting of non-patented drugs (generic drugs) 157 7.5 Price Competition 158 7.6 Cost controls 160 7.7 The prices a patient has to pay in the public sector in countries which have a public distribution system 163 7.8 Drug prices at private pharmacies in developing countries 164 7.9 The profits of drug companies 164 7.10 Summary 166 References 167 8 Drug wholesaling and procurement 171 8.1 Importation 172 8.2 Different types of wholesale systems 173 8.3 How to evaluate a wholesaling system 174 8.4 Procurement 176 8.5 Summary 178 References 178 9 Drug retail distribution 181 9.1 Pharmaceutical care 182 9.2 The degree of formal government control of outpatient pharmacies 184 9.3 Drug distribution aims 188 9.4 Summary 200 References 200 10 Drug consumption 205 10.1 Historical perspective 205 10.2 Measurement of drug consumption 206 10.3 Factors which determine the volume of a drug consumed in a country 209 10.4 Factors found to be related to the volume of drug consumption 211 10.5 Factors which influence drug consumption at the individual level 213 10.6 Qualitative studies of drug consumption 215 10.7 Summary 216 References 217 11 Marketing of drugs 219 11.1 Historical background 219 11.2 The contextual factors which affect the diffusion of a drug 221 11.3 The marketing goals of drug companies 222 11.4 Factors determining what a drug company spends on the marketing of a new drug 223 11.5 The relative effects of different media and messages in commercial drug information to prescribers 228 11.6 Commercial media directed at the general public 230 11.7 A national perspective on commercial drug information 230 11.8 Summary 233 References 233 12 The market structure 237 12.1 The existing international market structure 237 12.2 The market structure in a specific country 239 12.3 Summary 240 References 241 13 Drug control 243 13.1 Definition of drug control 243 13.2 Process model of the drug control system in a country 244 13.3 The processes to ensure that each aspect of drug control complies with the necessary norms or standards 247 13.4 Control measures 248 13.5 Clinical trials 251 13.6 Summary 251 References 252 14 Drug prescribing 255 14.1 Normative studies 255 14.2 Sociological studies 258 14.3 Information process studies of drug prescribing 260 14.4 Prescription studies based on a cognitive perspective 262 14.5 How standard selections change 267 14.6 Making a diagnosis 268 14.7 Placebo prescribing 269 14.8 Summary 270 References 271 15 Patients’ attitudes and behaviour 277 15.1 Background 277 15.2 Explanatory models 278 15.3 A process model: how a layperson deals with medical symptoms 280 15.4 OTC drugs 288 15.5 Patient compliance 289 15.6 Summary 294 References 294 16 Drug information 301 16.1 Background 301 16.2 The role of mass media 303 16.3 Drug information sources used 305 16.4 Drug information from a sender’s perspective 308 16.5 Mass media campaigns 313 16.6 The value problem 314 16.7 Summary 315 References 316 Index 319

Autorenportrait

Professor John Lilja, Department of Social Pharmacy, Finland. Professor Sam Salek, Reader in Pharmacoepidemiology; Director - WSP Centre for Socioeconomic Research; Director - Postgraduate Course in Pharmaceutical Medicine Cardiff University, UK. Dr Aldo Alvarez, San Marcos University, Lima, Peru, Dr David Hamilton, Widening Participation Service, Glasgow University, Glasgow.