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<b>1</b> <b>BIOGEOCHEMISTRY OF NICKEL AND ITS RELEASE INTO THE ENVIRONMENT</b> (<i>Tiina M. Nieminen, Liisa Ukonmaanaho, Nicole Rausch, and William Shotyk</i>). <p><b>2 NICKEL IN THE ENVIRONMENT AND ITS ROLE IN THE METABOLISM OF PLANTS AND CYANOBACTERIA</b> (<i>Hendrik Küpper and Peter M. H. Kroneck</i>).</p> <p><b>3 NICKEL ION COMPLEXES OF AMINO ACIDS AND PEPTIDES</b> (<i>Teresa Kowalik-Jankowska, Henryk Kozlowski, Etelka Farkas, and Imre Sóvágó</i>).</p> <p><b>4 COMPLEX FORMATION OF NICKEL(II) AND RELATED METAL IONS WITH SUGAR RESIDUES, NUCLEOBASES, PHOSPHATES, NUCLEOTIDES, AND NUCLEIC ACIDS</b> (<i>Roland K. O. Sigel and Helmut Sigel</i>).</p> <p><b>5</b> <b>SYNTHETIC MODELS FOR THE ACTIVE SITES OF NICKEL-CONTAINING ENZYMES</b> (<i>Jarl Ivar van der Vlugt and Franc Meyer</i>).</p> <p><b>6 UREASE: RECENT INSIGHTS ON THE ROLE OF NICKEL</b> (<i>Stefano Ciurli</i>).</p> <p><b>7 NICKEL IRON HYDROGENASES</b> (<i>Wolfgang Lubitz, Maurice van Gastel, and Wolfgang Gärtner</i>).</p> <p><b>8 METHYL-COENZYME M REDUCTASE AND ITS NICKEL CORPHIN COENZYME F₄₃₀ IN METHANOGENIC ARCHAEA</b> (<i>Bernhard Jaun and Rudolf K. Thauer</i>).</p> <p><b>9 ACETYL-COENZYME A SYNTHASES AND NICKEL-CONTAINING CARBON MONOXIDE DEHYDROGENASES</b> (<i>Paul A. Lindahl and David E. Graham</i>).</p> <p><b>10 NICKEL SUPEROXIDE DISMUTASE</b> (<i>Peter A. Bryngelson and Michael J. Maroney</i>).</p> <p><b>11 BIOCHEMISTRY OF THE NICKEL-DEPENDENT GLYOXALASE I ENZYMES</b> (<i>Nicole Sukdeo, Elisabeth Daub, and John F. Honek</i>).</p> <p><b>12 NICKEL IN ACIREDUCTONE DIOXYGENASE</b> (<i>Thomas C. Pochapsky, Tingting Ju, Marina Dang, Rachel Beaulieu, Gina M. Pagani, and Bo OuYang</i>).</p> <p><b>13</b> <b>THE NICKEL-REGULATED PEPTIDYL PROLYL <i>CIS/TRANS</i></b> <b>ISOMERASE SlyD</b> (<i>Frank Erdmann and Gunter Fischer</i>).</p> <p><b>14</b> <b>CHAPERONES OF NICKEL METABOLISM</b> (<i>Soledad Quiroz, Jong K. Kim, Scott B. Mulrooney, and Robert P. Hausinger</i>).</p> <p><b>15</b> <b>THE ROLE OF NICKEL IN ENVIRONMENTAL ADAPTATION OF THE GASTRIC PATHOGEN</b> <i><b>HELICOBACTER PYLORI</b></i> (<i>Florian D. Ernst, Arnoud H. M. van Vliet, Manfred Kist, Johannes G. Kusters, and Stefan Bereswill</i>).</p> <p><b>16</b> NICKEL-DEPENDENT GENE EXPRESSION (<i>Konstantin Salnikow and Kazimierz S. Kasprzak</i>).</p> <p><b>17 NICKEL TOXICITY AND CARCINOGENESIS</b> (<i>Kazimierz S. Kasprzak and Konstantin Salnikow</i>).</p> <p>SUBJECT INDEX.</p>

"All chapters of the book are authoritatively written by experts involved in the promotion of the field. The treatise is comprehensive, it presents latest information, the articles are well structured and easy to read and the text is fortified by numerous well-designed features.... A superb book which serves the novice, but even more the expert, in a this highly interdisciplinary field." (<i>Coordination Chemistry</i>, January 2009) <p>"All chapters of the book are authoritatively written by experts involved in the promotion of the field. The treatise is comprehensive, it presents that latest information, the articles are well structured and easy to read and the text is fortified by numerous well-designed features ... .This is a superb book which serves the novice, but even more the expert, in a this highly interdisciplinary field." (<i>Coordination Chemistry</i>, January 2009)</p> <p>"The biological role of nickel isn't a traditional category of science. I can't think of any departments dedicated to nickel biochemistry. All the more interesting then, to use this metal to slice across the established classifications and think outside the box." (<i>Chemistry and Industry</i>, December 2008)</p> <p>"Recommended for most academic libraries and research collections which support research in biological inorganic chemistry, geochemistry, plant soil sciences, environment, toxicity, and carcinogenesis." (<i>E-Streams</i>, September 2008)</p> <p>"Those unfamiliar with the field can learn a good deal about what was once a biological curiosity." (<i>Doody's Health Services</i>)</p> <p>"I particularly liked this book; the editors have done a great job of consolidating the many and varied aspects..."  (<i>Applied Organometallic Chemistry</i>, November 2007)</p>

<b>Astrid Sigel</b> has studied languages and was an editor of the <i>Metal Ions in Biological Systems</i> series (until Volume 44) and also of the <i>Handbooks on Toxicity of Inorganic Compounds</i> (1988), <i>on Metals in Clinical and Analytical Chemistry</i> (1994; both with H.G. Seiler), and on <i>Metalloproteins</i> (2001; with Ivano Bertini) (Dekker, New York). <p><b>Helmut Sigel</b> is <i>Emeritus</i> Professor (2003) of Inorganic Chemistry at the University of Basel, Switzerland, and a previous editor of the <i>MIBS</i> series until Volume 44. He serves on various editorial and advisory boards, published over 300 articles on metal ion complexes of nucleotides, coenzymes, and other ligands of biological relevance, and lectured worldwide. He was named <i>Protagonist in Chemistry</i> (2002) by <i>ICA</i> (issue 339); among further honors are the <i>P. Ray Award</i> (Indian Chemical Society, of which he is also an Honorary Fellow), the <i>Werner Award</i> (Swiss Chemical Society), a <i>Doctor of Science honoris causa</i> degree (Kalyani University, India), appointments as <i>Visiting Professor</i> (e.g., Austria, China, UK) and <i>Endowed Lectureships</i>.</p> <p><b>Roland K.O. Sigel</b> is Assistant Professor (2003) of Inorganic Chemistry at the University of Zürich, Switzerland, endowed with a <i>Förderungsprofessur</i> of the Swiss National Science Foundation. He received his doctoral degree <i>summa cum laude</i> (1999) from the University of Dortmund, Germany, working with Bernhard Lippert; thereafter he spent nearly three years at Columbia University, New York, USA, in the group of Anna Marie Pyle (now Yale University); during the six years abroad he received several fellowships from various sources. His research focuses on the structural and catalytic role of metal ions in ribozymes, especially group II introns, and on related topics. He was also an editor of Volumes 43 and 44 of the <i>MIBS</i> series.</p>

<b>Volume 2</b> focuses on the vibrant research area concerning nickel as well as its complexes and their role in Nature. With more than <b>2800</b> references and over <b>130</b> illustrations, it is an essential resource for scientists working in the wide range from inorganic biochemistry all the way through to medicine. <p>In <b>17</b> stimulating chapters, written by <b>47</b> internationally recognized experts, <b><i>Nickel and Its Surprising Impact in Nature</i></b> highlights critically the biogeochemistry of nickel, its role in the environment, in plants and cyanobacteria, as well as for the gastric pathogen <i>Helicobacter pylori</i>, for gene expression and carcinogenesis. In addition, it covers the complex-forming properties of nickel with amino acids, peptides, phosphates, nucleotides, and nucleic acids. The volume also provides sophisticated insights into the recent progress made in understanding the role of nickel in enzymes such as ureases, hydrogenases, superoxide dismutases, acireductone dioxygenases, acetyl-coenzyme A synthases, carbon monoxide dehydrogenases, methyl-coenzyme M reductases ... and it reveals the chaperones of nickel metabolism.</p>

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