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INTRODUCTION<br /> Neuroactive Substances<br /> Receptors and Transporters<br /> Distribution and Localization of Neurotransmitters and Neuromodulators<br /> The Blood-Brain Barrier<br /> Volume Transmission and Wiring Transmission<br /> METHODS FOR STUDYING NEUROACTIVE SUBSTANCES<br /> Bio- and Radioisotope Assays<br /> Microdialysis and Electrochemical Detection<br /> Chromatography<br /> Autoradiography<br /> Immunohistochemical Methods<br /> In-situ Hybridization<br /> Staining and Neuroanatomical Tract Tracing<br /> Electrophysiology<br /> Behavioral Testing<br /> Microarrays<br /> MALDI-TOF<br /> Neuroimaging<br /> Genomics und Proteomics Methods<br /> Databases<br /> NEUROTRANSMITTERS<br /> Acetylcholine<br /> Dopamine<br /> GABA (Gamma-Amino Butyric Acid)<br /> Glutamate and Aspartate<br /> Glycine<br /> Histamine<br /> Norepinephrine<br /> Serotonin (5-hydroxytryptamine)<br /> NEUROMODULATORS<br /> Adrenocorticotropic Hormone (ACTH)<br /> Anandamide<br /> Angiotensin<br /> Atrial Natriuretic Factor<br /> Calcitonin and Calcitonin Gene-Related Protein <br /> Cholecystokinin<br /> Corticotropin-Releasing Factor (CRF)<br /> Dynorphin<br /> Eicosanoids and Arachidonic Acid<br /> Endocannabinoids<br /> Endorphin<br /> Enkephalin<br /> FGF<br /> Galanin<br /> Growth Hormone-Releasing Hormone<br /> Gonadotropin-Releasing Hormone<br /> Interleukin<br /> Melanin-Concentrating Hormone<br /> Melanocyte-Stimulating Hormone <br /> Neurotensin<br /> Neutrophins<br /> Nitric Oxide<br /> Nociceptin (Orphanin FQ)<br /> Neuropeptide Y<br /> PACAP (pituitary adenylate cyclase-activating polypeptide)<br /> Proopiomelanocortin<br /> Purines<br /> Somatostatin<br /> Substance P and Tachykinins<br /> Thyrotropin-Releasing Hormone<br /> Tyr-MIF-1 Family<br /> Vasoactive Intestinal Polypeptide (VIP)<br /> Vasopressin and Oxytocin

Oliver von Bohlen und Halbach gained his PhD in biology at the University of Constance, Germany. He carried out his postdoctoral training at the Medical Faculty, Charité, of the Humboldt-University in Berlin. Since 2001 he is postdoctoral fellow at the Interdisciplinary Center for Neurosciences at the Medical Faculty of the University of Heidelberg, Germany.<br /> <br /> Rolf Dermietzel obtained his MD in 1970 at the Medical School Essen, Germany, where he continued his training, being appointed as Associate Professor 1976. In 1984 he started a research fellowship at the California Institute of Technology, Pasadena followed by a position as Visiting Professor at the Albert-Einstein College of Medicine, New York, in 1988. One year later he became Chairman of the Institute of Anatomy at the University of Regensburg, Germany, and in 1998 Chairman of the Institute of Anatomy at the University of Bochum, Germany.

A Complete update of the highly acclaimed handbook with data on all neurotransmitters and the majority of neuromodulators - now in full color throughout. The coverage is even more comprehensive, with additional entries on neuropeptides, "Classic" Neurotransmitters and related substances in a clear, alphabetical format. the methodological section has been expanded by 50%, covering proteomics, databases, microarrays, MALDI-TOF, and neuroimaging. <p>The text provides clearly structured information on the biosynthesis and degradation, localization, receptors, signal transduction pathways, and biological effects in the central nervous system, with all substances uniformly treated for an easy comparison of data. A new section on neurological disorders and neurodegenerative diseases has been added for each substance. Furthermore, introductory chapters on receptors, transporters, and the blood-brain barrier make this an indispensable tool for researchers, teachers, and advanced students, as well as a must-have for every neuroscientist.</p>

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