Details

Marine Microbiology


Marine Microbiology

Bioactive Compounds and Biotechnological Applications
1. Aufl.

von: Se-Kwon Kim

183,99 €

Verlag: Wiley-VCH
Format: EPUB
Veröffentl.: 21.06.2013
ISBN/EAN: 9783527665273
Sprache: englisch
Anzahl Seiten: 580

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Beschreibungen

Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues.<br> <br> Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.<br> <br>
PREFACE <br> <br> INTRODUCTION TO MARINE ACTINOBACTERIA<br> Introduction<br> Actinobacteria <br> Origin and Distribution of Marine Actinobacteria <br> Isolation and Identification of Marine Actinobacteria <br> Indigenous Marine Actinobacteria <br> Role of Actinobacteria in the Marine Environment<br> Importance of Marine Actinobacteria <br> Symbioses <br> Bioinformatics <br> Conclusions <br> <br> TREASURE HUNTING FOR USEFUL MICROORGANISMS IN THE MARINE ENVIRONMENT <br> Introduction <br> Microorganisms Living in the Marine Environment<br> Microorganisms Living in Deep Sea Water <br> <br> STRATEGY OF MARINE VIRUSES IN GLOBAL ECOSYSTEM<br> Introduction <br> Reproductive Strategies of Viruses <br> Abundance of Marine Viruses<br> Viral Activities in Ecosystems <br> Recent Advancement of Viruses versus Diseases <br> The Effect of Ocean Acidification on Marine Viruses <br> Further Aspects<br> <br> TAXONOMIC STUDY OF ANTIBIOTIC-PRODUCING MARINE ACTINOBACTERIA <br> Introduction <br> Materials and Methods <br> Result <br> Discussion <br> Conclusion <br> <br> MARINE CYANOBACTERIA: A PROLIFIC SOURCE OF BIOACTIVE NATURAL PRODUCTS AS DRUG LEADS <br> Introduction <br> Bioactive Secondary Metabolites from Marine Cyanobacteria<br> Conclusions <br> <br> MARINE BACTERIA ARE AN ATTRACTIVE SOURCE TO OVERCOME THE PROBLEMS OF ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS AUREUS<br> Introduction <br> Strategies for Overcoming Antibiotic Resistance of Bacteria <br> Marine Bacteria Are Attractive Natural Sources for Overcoming Antibiotic Resistance of MRSA <br> <br> MARINE BACTERIA AS PROBIOTICS AND THEIR APPLICATIONS IN AQUACULTURE <br> Introduction <br> Definition of Probiotics in Aquaculture <br> Selecting and Developing Probiotics in Aquaculture <br> Effects of Probiotics on Aquatic Organisms <br> Probiotics in the Larviculture 1<br> Problems Associated with Probiotics Development <br> Further Work and Conclusions <br> <br> SMALL-MOLECULE ANTIBIOTICS FROM MARINE BACTERIA AND STRATEGIES TO PREVENT REDISCOVERY OF KNOWN COMPOUNDS <br> Antibiotic Activity of Marine Bacteria <br> Structurally Elucidated Marine Bacterial Antibiotics <br> Cosmopolitan Antibiotics: the Rediscovery Problem <br> Future Strategies for the Discovery of Marine Bacterial Antibiotics <br> Conclusions and Perspectives <br> <br> MARINE BACTERIOPHAGES FOR THE BIOCONTROL OF FISH AND SHELLFISH DISEASES<br> Introduction <br> Mode of Action of Phages <br> Diversity of Marine Phages <br> Application of Marine Phages to Control Fish and Shellfish Diseases <br> Potentials and Limitations of Phage Therapy in Marine Fish and Shellfish <br> <br> MARINE ACTINOMYCETES AS SOURCE OF PHARMACEUTICALLY IMPORTANT COMPOUNDS <br> Introduction <br> Marine Actinomycetes as Source of Therapeutics <br> Marine Actinomycete Compounds as Antibacterials <br> Marine Actinomycete Compounds as Antitumors/Antiproliferative <br> Marine Actinomycete Enzymes as Antiproliferatives <br> Marine Actinomycete Compounds as Antimalarials <br> Marine Actinomycete Compounds as Antifungals <br> Bioactive Compounds from Sponge-Associated Actinomycetes <br> Conclusion <br> <br> ANTIMICROBIAL AGENTS FROM MARINE CYANOBACTERIA AND ACTINOMYCETES <br> Introduction <br> Antimicrobials from Marine Actinomycetes <br> Antimicrobials from Marine Cyanobacteria<br> Current Research Status: Challenges and Future Prospects <br> Conclusions <br> <br> BIOACTIVE COMPOUNDS FROM MARINE ACTINOMYCETES <br> Introduction<br> Actinomycetes <br> Diversity and Distribution of Marine Actinobacteria <br> Bioactive Compounds <br> Conclusions <br> <br> FUNGAL BIOACTIVE GENE CLUSTERS: A MOLECULAR INSIGHT <br> Introduction to Fungal Secondary Metabolites <br> Polyketide Synthase <br> Nonribosomal Peptide Synthetase <br> PKS and NRPS Products <br> Conclusions <br> <br> ANTICANCER POTENTIALS OF MARINE-DERIVED FUNGAL METABOLITES <br> Introduction <br> Marine Fungi <br> Cancer: Initiation, Progression, and Therapeutics <br> Anticancer Metabolites of Marine Fungal Origin<br> Future Prospects and Concluding Remarks<br> <br> ANTIFUNGAL AND ANTIMYCOTOXIN ACTIVITIES OF MARINE ACTINOMYCETES AND THEIR COMPOUNDS <br> Introduction <br> Diversity of Actinomycetes in the Sea <br> Diversity of Natural Compounds from Marine Actinomycetes<br> Biological Activities<br> Conclusions <br> <br> ANTITUBERCULOSIS MATERIALS FROM MARINE MICROBES <br> Introduction <br> Marine Microbe-Derived Antituberculosis Agents <br> Conclusions <br> <br> HARNESSING THE CHEMICAL AND GENETIC DIVERSITIES OF MARINE MICROORGANISMS FOR MEDICAL APPLICATIONS<br> Introduction<br> Novel MNPs <br> Gene-Based Studies of MNPs <br> MNPs Discovery Using Genome Mining <br> Conclusion and Prospects <br> <br> MARINE SYMBIOTIC MICROORGANISMS: A NEW DIMENSION IN NATURAL PRODUCT RESEARCH<br> Introduction <br> Marine Microorganisms and Their Symbiotic Relationships <br> Biologically Active Metabolites of Marine Symbiotic Microbes <br> Concluding Remarks <br> <br> APPLICATION OF PROBIOTICS FROM MARINE MICROBES FOR SUSTAINABLE MARINE AQUACULTURE DEVELOPMENT<br> Introduction<br> The Application of Probiotics for Marine Fishes <br> The Application of Probiotics for Marine Crustaceans <br> The Application of Probiotics for Marine Mollusks <br> <br> ANTIMICROBIAL PROPERTIES OF EICOSAPENTAENOIC ACID (C20 : 5N_3)<br> Introduction<br> Spectrum of Antimicrobial Activity and Potency <br> Structure Relationship with Activity <br> Mechanism of Antimicrobial Action <br> Safety, Delivery, and Biotechnological Application <br> Concluding Remarks <br> <br> BIOPROSPECTING OF MARINE MICROBIAL SYMBIONTS: EXPLOITATION OF UNDEREXPLORED MARINE MICROORGANISMS <br> Introduction <br> Marine Microbial Symbionts<br> Bioethical and Supply Issues in Utilizing Marine Invertebrates<br> Marine Fungal Symbionts of Corals as Sustainable Sources of Marine Natural Products<br> Marine Actinomycete Symbionts as Prolific Marine Natural Products <br> New Avenue of Research: Marine Natural Products from Fungal Symbionts of Corals<br> Concluding Remarks <br> <br> MARINE MICROORGANISMS AND THEIR VERSATILE APPLICATIONS IN BIOACTIVE COMPOUNDS <br> Introduction<br> Separation and Isolation Techniques of Bioactive Compounds from Marine Organisms <br> Different Bioactive Compounds from Marine Organisms<br> Polysaccharides <br> Pigments <br> Conclusions <br> <br> METABOLITES OF MARINE MICROORGANISMS AND THEIR PHARMACOLOGICAL ACTIVITIES <br> Introduction<br> Marine Fungi <br> Marine Actinomycetes <br> Marine Cyanobacteria<br> Conclusions <br> <br> SPONGES: A RESERVOIR FOR MICROORGANISM-DERIVED BIOACTIVE METABOLITES <br> Introduction <br> Collection of Sponges and Associated Microbes <br> Bacteria <br> Unidentified Bacteria <br> Fungi <br> Unidentified Fungal Strains from Sponges <br> Compounds in Clinical Trial and Use <br> Conclusions<br> <br> BIOACTIVE MARINE MICROORGANISMS FOR BIOCATALYTIC REACTIONS IN ORGANIC COMPOUNDS<br> Introduction <br> Marine Enzymes<br> Biotransformation of Natural Products by Marine Biocatalysts<br> Biodegradation of Organic Compounds by Marine Biocatalysts <br> Reduction of Carbonyl Groups (Ketones and Keto Esters) by Marine Biocatalysts <br> Hydrolysis of Epoxides by Marine Biocatalysts <br> Collection and Isolation of Bioactive Marine Microorganisms <br> Conclusions and Perspectives <br> <br> MARINE MICROBIAL ENZYMES: BIOTECHNOLOGICAL AND BIOMEDICAL ASPECTS <br> Introduction <br> Extremozymes: Most Potential Marine Enzymes <br> Biotechnological Aspects <br> Biomedical Aspects <br> Concluding Remarks and Perspectives <br> <br> BIOMEDICAL APPLICATIONS OF MYCOSPORINE-LIKE AMINO ACIDS <br> Introduction<br> Mycosporine-Like Amino Acids (MAAs)<br> Distribution of MAAs<br> Genetic Control of MAAs Synthesis <br> MAAs Induction<br> Biomedical Potentials of MAAs <br> MAAs as Photoprotectants<br> MAAs as an Antioxidant <br> MAAs as Blocker of Dimer Formation <br> MAAs as an Osmoregulator <br> Conclusions and Future Prospects <br> <br> INDEX<br>
<b>Se-Kwon Kim</b> is Professor of Marine Biochemistry at Pukyong National University in Busan, South Korea. A graduate of PKNU, he conducted his postdoctoral studies at the University of Illinois (USA), and was a visiting scientist at the Memorial University of Newfoundland (Canada). His major research interests are the investigation and development of bioactive substances derived from marine organisms and their application as cosmeceuticals and nutraceuticals. Professor Kim is the current editor-in-chief of the <i>Korean Journal of Marine Bioscience and Biotechnology</i>. He has authored over 450 research papers, holds 72 patents, and has written or edited more than 30 books.
Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or<br />cosmetics, from prospecting to production issues.<br /><br />Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.

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