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<p>Preface xxiii</p> <p>Foreword xxv</p> <p>List of Contributors xxvii</p> <p><b>Section I Epilepsy: Epidemiology, Diagnostic Evaluation and Co-Morbidities 1</b></p> <p>1 Introduction and Epidemiology 3<br /><i>Joseph I. Sirven and Gregory D. Cascino</i></p> <p>2 Classification of Seizures and the Epilepsies 11<br /><i>Elaine C. Wirrell</i></p> <p>3 Etiology and Pathology of Epilepsy 23<br /><i>Katherine C. Nickels and Katherine Noe</i></p> <p>4 Genetics of Epilepsy 37<br /><i>Anthony L. Fine, Lily C. Wong-Kisiel and Raj D. Sheth</i></p> <p>5 Burden of Epilepsy 63<br /><i>J. Layne Moore, Amy Z. Crepeau and Gregory D. Cascino</i></p> <p>6 EEG and Epilepsy 77<br /><i>Anteneh M. Feyissa, Gregory A. Worrell and Terrence D. Lagerlund</i></p> <p>7 Neuroimaging in Epilepsy 99<br /><i>Benjamin H. Brinkmann, Elson L. So, Robert E. Watson and Amy L. Kotsenas</i></p> <p>8 The Evaluation of Nonepileptic Paroxysmal Events 117<br /><i>Sara Dawit and Joseph F. Drazkowski</i></p> <p>9 Sleep, Sleep Disorders, and Epilepsy 133<br /><i>Diego Z. Carvalho, J. Layne Moore and Erik K. St. Louis</i></p> <p>Epilepsy Journey: Identification of a Genetic Etiology for Epilepsy 147<br /><i>Anthony L. Fine, Lily C. Wong-Kisiel and Raj D. Sheth</i></p> <p>Epilepsy Journey 2: Evaluation of Spells in Adults 153<br /><i>David B. Burkholder</i></p> <p>Epilepsy Journey 3: The Pediatric Patient with Spells: Recommendations for Evaluation 157<br /><i>Katherine C. Nickels and Elaine C. Wirrell</i></p> <p>Epilepsy Journey 4: Transitioning from Pediatric to Adult Epilepsy Clinic 165<br /><i>Gregory D. Cascino, Katherine C. Nickels and Elaine C. Wirrell</i></p> <p><b>Section II Epilepsy: Treatment of Epilepsy: Non-Surgical Therapy 169</b></p> <p>10 First Seizure 171<br /><i>Scott Spritzer and Omar Danoun</i></p> <p>11 Antiseizure Medication Therapy 179<br /><i>Kiran M. Kanth, Sarah Clark and Jeffrey W. Britton</i></p> <p>12 Epilepsy in Women 217<br /><i>Katherine Noe</i></p> <p>13 Treating Children with Epilepsy: Antiepileptic Medications (AEDs) 229<br /><i>Raj D. Sheth</i></p> <p>14 Dietary Therapy in Epilepsy 239<br /><i>Katherine C. Nickels and Elaine C. Wirrell</i></p> <p>15 Autoimmune Epilepsy Disorders 249<br /><i>Jeffrey W. Britton, Eoin P. Flanagan, Andrew McKeon and Sean J. Pittock</i></p> <p>16 Discontinuation of Antiseizure Medication 275<br /><i>Jamal F. Khattak and Jeffrey W. Britton</i></p> <p>17 Investigational Therapy and Drug Approval Process within the US and Cannabidiol 287<br /><i>Gregory Sprout, Joseph I. Sirven and Gregory D. Cascino</i></p> <p>18 Devices to Monitor and Track Your Epilepsy 301<br /><i>Nicholas M. Gregg and Amy Z. Crepeau</i></p> <p>Epilepsy Journey 5: Seizure Emergencies (Include status Epilepticus, Fires, Norse, Seizure First Aid, and Seizure Clusters) 313<br /><i>Anteneh M. Feyissa, Matthew T. Hoerth and Eric T. Payne</i></p> <p>Epilepsy Journey 6: The First seizure -- How to Evaluate: Pediatric 315<br /><i>Korwyn Williams</i></p> <p>Epilepsy Journey 7: The First Seizure -- How to Evaluate: Adult 317<br /><i>Paul M. Magtibay and Joseph I. Sirven</i></p> <p>Epilepsy Journey 8: Treating Epilepsy Second Seizure and beyond: How to Choose a Drug -- An Algorithm 321<br /><i>Amy Z. Crepeau</i></p> <p>Epilepsy Journey 9: Treating Status Epilepticus: An Algorithm 325<br /><i>Sara E. Hocker and Eric T. Payne</i></p> <p>Epilepsy Journey 10: Withdrawal of ASDs in Adults: An Algorithm 331<br /><i>Sarah A. Merrill, Kent R. Richter and Joseph I. Sirven</i></p> <p>Epilepsy Journey 11: Withdrawal of ASDs in Seizure-Free Patients Children: The Pediatric<br />Neurologist’s Perspective 335<br /><i>Elaine C. Wirrell</i></p> <p>Epilepsy Journey 12: Withdrawing ASDs in Adults after Epilepsy Surgery 339<br /><i>Christian Rosenow, Luca Farrugia, Andrew Pines and Joseph I. Sirven</i></p> <p>Epilepsy Journey 13: The Pregnant Patient with Epilepsy: An Algorithm 343<br /><i>Katherine Noe</i></p> <p><b>Section III Epilepsy: Treatment of Epilepsy: Surgical Management 345</b></p> <p>19 Pre-surgical Evaluation 347<br /><i>David B. Burkholder, Anthony L. Ritaccio and Cheolsu Shin</i></p> <p>20 Minimally Invasive Epilepsy Surgery 367<br /><i>Sanjeet S. Grewal, Robert E. Wharen Jr. and William O. Tatum</i></p> <p>21 Intracranial EEG Monitoring 381<br /><i>Jamie J. Van Gompel, Katherine Noe and Richard S. Zimmerman</i></p> <p>22 Surgical Strategies (Include Cortical Resection, Lesionectomy, Cortical Stimulation and Functional Mapping, Hemispherotomy) 401<br /><i>Angela Bohnen, W. Richard Marsh, Alfredo Quinones-Hinojosa and Kaisorn L. Chaichana</i></p> <p>23 Corpus Callosotomy 413<br /><i>Elaine C. Wirrell, Lily C. Wong-Kisiel and Kai J. Miller</i></p> <p>24 Neuromodulation for Epilepsy 431<br /><i>Brian N. Lundstrom, Robert E. Wharen, Jr and William O. Tatum</i></p> <p>25 Emerging Treatments for Epilepsy 441<br /><i>Gregory A. Worrell, Benjamin H. Brinkmann, Brian N. Lundstrom and Matt Stead</i></p> <p>26 Seizure Forecasting in Epilepsy: From Computation to Clinical Practice 451<br /><i>Benjamin H. Brinkmann, Nicholas M. Gregg and Gregory A. Worrell</i></p> <p>Epilepsy Journey 14: The Drug-Resistant Patient: Pre-surgical Evaluation and Surgery-Approach to the "Skip" Candidate 463<br /><i>Anteneh M. Feyissa and David B. Burkholder</i></p> <p>Epilepsy Journey 15: The Drug-Resistant Patient and Discordant Pre-surgical Evaluation 469<br /><i>Lily C. Wong-Kisiel, Elson L. So and Richard S. Zimmerman</i></p> <p>Epilepsy Journey 16: The Drug-Resistant Patient who is not a Candidate for Resective Surgery: An Approach to Neuromodulation 477<br /><i>Anthony L. Ritaccio and William O. Tatum</i></p> <p>Epilepsy Journey 17: Epilepsy Surgery in Pediatric Patients 483<br /><i>Raj D. Sheth, Kai J. Miller and Elaine C. Wirrell</i></p> <p>References 489</p> <p>Index 491</p>

<p><b>GREGORY D. CASCINO</b> is the Whitney MacMillan, Jr. Professor of Neuroscience at the Mayo Clinic, Rochester, MN, USA. <p><b>JOSEPH I. SIRVEN</b> is Professor of Neurology at the Mayo Clinic, Jacksonville, FL, USA. <p><b>WILLIAM O. TATUM</b> is Professor of Neurology at the Mayo Clinic, Jacksonville, FL, USA.

<p><b>A practical resource for all those working with epilepsy patients</b> <p>The revised second edition of <i>Epilepsy</i> brings together the latest research, methods and best-practice guidelines to create a complete guide to the diagnosis and management of this complex neurological disorder. Covering all clinical features associated with epilepsy, it provides practical guidance on issues encountered in everyday practice, as well addressing the condition’s underlying causes and the various strategies through which it can be mitigated and controlled. Topics covered by the book’s wide-ranging chapters include pharmacological interaction and adverse effects, alternative therapies, patient experience, epilepsy in pregnant patients, and more. <p>In addition, the second edition of <i>Epilepsy</i> contains brand-new material on:<BR> <ul> <li>Stereotactic electroencephalography</li> <li>Chronic intracranial electronic stimulation for management of DRE</li> <li>Gene mutations and epilepsy</li> <li>Functional connectivity and network hypothesis of epilepsy</li> <li>Laser ablation therapy</li> <li>Quantitative MRI neuroimaging</li> <li>Neuropsychology devices for epilepsy</li> </ul> <p>Assembled by a global team of experts and seasoned practitioners, <i>Epilepsy</i> is an indispensable tool for all those working in the field today.

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