Details

<p>List of contributors vii</p> <p>Foreword xi</p> <p>List of abbreviations xiii</p> <p><b>Part 1: Diagnosis and pathophysiology</b></p> <p>1 Clinical clues to the diagnosis of cirrhosis 3<br /><i>Y.K. Chawla and Vijay Bodh</i></p> <p>2 Diagnostic laboratory tests 12<br /><i>Ying-Ying Yang and Han-Chieh Lin</i></p> <p>3 Diagnostic imaging modalities 21<br /><i>Soon Koo Baik Moon Young Kim and Woo Kyoung Jeong</i></p> <p>4 Histology/pathology 35<br /><i>Valérie Paradis</i></p> <p>5 Fibrosis and fibrogenesis 46<br /><i>Namiki Izumi Nobuharu Tamaki Yasuhiro Asahina and Masayuki Kurosaki</i></p> <p>6 Non-invasive diagnosis tests 53<br /><i>Laurent Castera</i></p> <p>7 Evaluating prognosis 63<br /><i>Sumeet K. Asrani and Patrick S. Kamath</i></p> <p>8 End-stage liver failure: liver transplant evaluation 75<br /><i>Sebastián Marciano and Adrián Gadano</i></p> <p><b>Part 2: Complications of cirrhosis</b></p> <p>9 Acute-on-chronic liver failure 87<br /><i>Danielle Adebayo Vincenzo Morabito and Rajiv Jalan</i></p> <p>10 Hepatocellular carcinoma 94<br /><i>Kwang-Hyub Han and Do Young Kim</i></p> <p>11 Hepatic encephalopathy 105<br /><i>Piero Amodio</i></p> <p>12 Malnutrition and nutritional support 124<br /><i>Jian-Gao Fan and Hai-Xia Cao</i></p> <p>13 Varices portal hypertensive gastropathy and GAVE 137<br /><i>Isabelle Colle Xavier Verhelst Anja Geerts and Hans Van Vlierberghe</i></p> <p>14 Ascites 151<br /><i>Andrés Cárdenas Isabel Graupera and Pere Ginès</i></p> <p>15 Spontaneous bacterial peritonitis and other infections 164<br /><i>Thierry Gustot and Richard Moreau</i></p> <p>16 Hepatorenal syndrome and acute kidney injury 175<br /><i>Florence Wong</i></p> <p>17 The hepatopulmonary syndrome 189<br /><i>Moises Ilan Nevah Rubin and Michael B. Fallon</i></p> <p>18 Hyponatremia and other electrolyte/ion disorders 199<br /><i>Salvatore Piano Filippo Morando and Paolo Angeli</i></p> <p>19 Portopulmonary hypertension 212<br /><i>Rodrigo Cartin-Ceba and Michael J. Krowka</i></p> <p>20 Cirrhotic cardiomyopathy 225<br /><i>Hongqun Liu and Samuel S. Lee</i></p> <p>21 Adrenal insufficiency 236<br /><i>Emily Dannhorn and James O’Beirne</i></p> <p>22 Coagulopathy and clotting disorders 249<br /><i>Marco Senzolo and A.K. Burroughs</i></p> <p>23 Agents and drugs: precautions in patients with cirrhosis 261<br /><i>Felix Stickel</i></p> <p>24 Changing outcomes with antiviral or antifibrotic therapies 274<br /><i>Gamal Esmat and Maissa El Raziky</i></p> <p>25 Bone disorders 283<br /><i>Jane Collier</i></p> <p>26 Pruritus 291<br /><i>Nora V. Bergasa</i></p> <p>27 Quality of life and symptom management 301<br /><i>Ayman A. Abdo and Faisal M. Sanai</i></p> <p>28 Special considerations in children 311<br /><i>Alejandro Costaguta and Fernando Alvarez</i></p> <p>Index 323</p>

<p><b>Samuel S. Lee</b>, MD, Professor, Department of Medicine and Head, Division of Gastroenterology, University of Calgary, Canada. Sam Lee is one of the world’s leading lights on cirrhosis and is editor-in-chief of the Wiley journal <i>Liver International</i>, the official journal of the International Association for the Study of the Liver.</p> <p><b>Richard Moreau</b>, MD, Head and Director of Research at the National Institute of Health (Inserm), Paris, France.</p>

<p><i>Cirrhosis: A practical guide to management</i> provides gastroenterologists and hepatologists with the very best evidence-based practice in the diagnosis, treatment, and management of liver cirrhosis and its many complications. Designed to offer practical guidance at all times, chapters include diagnostic/management algorithms, key points, and other pedagogic features.</p> <p>The books is divided into two parts: a diagnosis and pathophysiology section and a management of complications section. Key topics include:</p> <p>• Diagnostic laboratory tests</p> <p>• Diagnostic imaging modalities</p> <p>• Acute-on-chronic liver failure</p> <p>• Agents and drugs to avoid</p> <p>• End-stage liver failure: liver transplant evaluation</p> <p>• Hepatocellular carcinoma</p> <p>Perfect for both specialists and specialty trainees, emphasis throughout is on providing clear, clinical management guidance to enable doctors to manage their patients quicker and more effectively. It is an invaluable guide to what is an increasingly common condition.</p>

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