Biopolymers for Biomedical and Biotechnological Applications
Advanced Biotechnology 1. Aufl.
Provides insight into biopolymers, their physicochemical properties, and their biomedical and biotechnological applications <br> <br> This comprehensive book is a one-stop reference for the production, modifications, and assessment of biopolymers. It highlights the technical and methodological advancements in introducing biopolymers, their study, and promoted applications.<br> <br> "Biopolymers for Biomedical and Biotechnological Applications" begins with a general overview of biopolymers, properties, and biocompatibility. It then provides in-depth information in three dedicated sections: Biopolymers through Bioengineering and Biotechnology Venues; Polymeric Biomaterials with Wide Applications; and Biopolymers for Specific Applications. Chapters cover: advances in biocompatibility; advanced microbial polysaccharides; microbial cell factories for biomanufacturing of polysaccharides; exploitation of exopolysaccharides from lactic acid bacteria; and the new biopolymer for biomedical application called nanocellulose. Advances in mucin biopolymer research are presented, along with those in the synthesis of fibrous proteins and their applications. The book looks at microbial polyhydroxyalkanoates (PHAs), as well as natural and synthetic biopolymers in drug delivery and tissue engineering. It finishes with a chapter on the current state and applications of, and future trends in, biopolymers in regenerative medicine.<br> <br> * Offers a complete and thorough treatment of biopolymers from synthesis strategies and physiochemical properties to applications in industrial and medical biotechnology<br> * Discusses the most attracted biopolymers with wide and specific applications<br> * Takes a systematic approach to the field which allows readers to grasp and implement strategies for biomedical and biotechnological applications<br> <br> "Biopolymers for Biomedical and Biotechnological Applications" appeals to biotechnologists, bioengineers, and polymer chemists, as well as to those working in the biotechnological industry and institutes.<br>
Introduction (by Editors)<br> Editor<br> Contributors <br> <br> Part I. General Overview of Biopolymers<br> Chapter 1 Biopolymers: State of the Art, New Challenges, and Opportunities<br> Chapter 2 Biopolymers Properties: Structure, Rheological and Gelation Properties<br> Chapter 3 Advances in Biocompatibility: a prerequisite for biomedical application of biopolymers<br> <br> Part II. Polymeric Biomaterials with wide applications<br> Chapter 4 Advanced Polysaccharides from bacteria: Alginate, Xanthan, Cellulose and hemicellulose, etc) (Structure, properties, biosynthesis, production, engineering, modifications, applications) <br> Chapter 5 Advanced polymeric materials from fungi: Polysaccharides (chitin, cellulose, etc) (Structure, properties, biosynthesis, production, engineering, modifications, applications)<br> Chapter 6 Exploitation of Exopolysaccharides from Lactic Acid Bacteria<br> Chapter 7 Advances in Levan biopolymers and their applications: Structure, properties, biosynthesis, production, engineering, modifications, applications<br> Chapter 8 Advances in Hyaluronic acid biopolymers: Structure, properties, biosynthesis, production, engineering, modifications, applications<br> Chapter 9 Sulfated Polysaccharides and their applications: Structure, properties, biosynthesis, production, engineering, modifications, applications<br> Chapter 10 Advances in Cyanophycin biopolymers and their applications: Structure, properties, biosynthesis, production, engineering, modifications, applications <br> Chapter 11 Advances in Poly(gamma-glutamic acid) biopolymers and their production and applications: Structure, properties, biosynthesis, production, engineering, modifications, applications<br> Chapter 12 Advances in microbial production of fibrous proteins and their applications<br> Chapter 13 Advances in production and applications of organic compound based biopolymers<br> Chapter 14 Advances in Microbial glycoproteins and their applications<br> Chapter 15 Advances in Mucin biopolymers and their biomedical applications: Structure, properties, biosynthesis, production, engineering, modifications, applications<br> Chapter 16 Nucleic acid-based hydrogels and their applications<br> Chapter 17 Nucleic acid-based nanostructures and their applications<br> <br> Part III. Biopolyemrs through Bioengineering and Biotechnology Venues<br> Chapter 18 Systems biology for Microbial Production of Biopolymers<br> Chapter 19 Metabolic Engineering of Microorganisms for Polysaccharides Production<br> Chapter 20 Engineering cell factories for producing tailor-made biopolymers and chemical building blocks<br> Chapter 21 Engineering microbial protein glycosylation and application<br> Chapter 22 Molecular self-assembly for developing biological materials<br> Chapter 23 Advances in Biopolymers Processing<br> Chapter 24 Advances in Development of Biopolymer Films, biocomposites, and Macro-, Micro-, and Nanocomposites<br> <br> Part IV. Biopolymers for Specific Applications<br> Chapter 25 Biopolymers in Regenerative Medicine and Tissue Engineering: Overview, Current Advances, and Future Trends<br> Chapter 26 Biopolymers in Controlled-Release Delivery Systems<br> Chapter 27 Advances in Biopolymer Composite Materials with Antimicrobial Effects<br> Chapter 28 Advances in Biopolymer-based Nanoparticles for Theranostics Applications<br> Chapter 29 Advances in Biopolymers application in Dentistry<br> Chapter 30 Advances in Biomaterials-Based Electronics<br> Chapter 31 Biopolymers for Biosensors
Bernd Rehm received his MSc and PhD degrees (microbiology) from the Ruhr University Bochum, Germany, in 1991 and 1993, respectively. He continued as a postdoc at the Department of Microbiology and Immunology at the University of British Columbia, Canada. From 1996 to 2003, he was a research group leader at the Institute of Molecular Microbiology and Biotechnology at the University of Münster, Germany, where he also completed his habilitation. In 2003 he was appointed as Associate Professor and in 2005 promoted to Full Professor/Chair of Microbiology at Massey University in New Zealand. From 2013 to 2016 he was principal investigator of the Centre of Research Excellence (New Zealand) at the MacDiarmid Institute of Advanced Materials and Nanotechnology. He was recently appointed as Director of the Centre for Cell Factories and Biopolymer at Griffith University (Griffith Institute for Drug Discovery, Australia), and is the founder and chief technology officer of the biotechnology start-up company PolyBatics Ltd.<br> He is editor-in-chief and editor of 5 scientific journals as well as an editorial board member of 10 scientific journals and the sole editor of 5 books. He has authored over 200 scientific publications, and holds more than 30 patents. His R&D interests are in the microbial production of polymers and their applications. His recent studies focused on the use of engineered microorganisms to produce functionalized nano-/micro-structures for applications in diagnostics, enzyme immobilization, and antigen delivery.<br> <br> Dr. Fata Moradali received his MSc degree from Tehran University and his PhD degree in molecular microbiology and genetics from Massey University, New Zealand. Early years of his career were spend for investigating bioactive components from natural resources particularly fungi. Then, it was followed by spending several years in Prof. Bernd Rehm`s laboratory investigating molecular mechanism of alginate biosynthesis and signaling pathways in the model organism Pseudomonas aeruginosa. He then moved to the Department of Oral Biology, Florida University, USA, to join Dr. Mary Ellen Davey`s laboratory to continue cutting-edge research in the field of human oral biology and microbiota. Dr. Moradali has contributed to our understanding of bacterial physiology and pathogenesis and the molecular mechanism of alginate biosynthesis in P. aeruginosa as a model organism. His research has provided new insights into the molecular mechanism of alginate polymerization/modification and its activation by bacterial second messenger cyclic di-GMP. By employing genetic engineering in his research, he demonstrated the production of various alginates from P. aeruginosa for the production of tailor- made alginate. He has extensive expertise in microbial genetics and physiology with respect to pathogenesis as well as production of microbial compounds.