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<i>List of Contributors.</i> <p><i>Foreword.</i></p> <p><i>Preface.</i></p> <p><b>Part 1 The Science of Genomics and Genetics.</b></p> <p>1 The Human Genome and Epigenome (john j. mulvihill, klaas j. wierenga and chad m. kerksick).</p> <p>2 Mitochondrial Medicine in Health and Disease: Interface Between Athletic Performance and Therapeutics (douglas c. wallace).</p> <p>3 Characterizing the Extent of Human Genetic Variation for Performance-Related Traits (john blangero and jack w. kent jr.).</p> <p>4 Current Proteome Profiling Methods (yetrib hathout, catherine a. formolo, kristy j. brown and javad nazarian).</p> <p>5 Bioinformatics and Public Access Resources (yue wang, huai li, david j. miller and jianhua xuan).</p> <p>6 Search for Genes Influencing Complex Traits (corneliu henegar, henri hooton and karine clément).</p> <p><b>Part 2 Evidence from Genetic Epidemiology Studies.</b></p> <p>7 Genetic Epidemiology, Physical Activity, and Inactivity (molly s. bray, janet e. fulton, nishan sudheera kalupahana and j. timothy lightfoot).</p> <p>8 Role of Genetics Factors in Sport Performance: Evidence from Family Studies (louis pérusse).</p> <p>9 Twin Studies in Sport Performance (gaston p. beunen, maarten w. peeters and robert m. malina).</p> <p>10 Twin and Family Studies of Training Responses (mark a. sarzynski, tuomo rankinen and claude bouchard).</p> <p>11 Ethnic Differences in Sport Performance (yannis p. pitsiladis).</p> <p>12 Selection Experiments in Rodents to Define the Complexity and Diversity of Endurance Capacity (steven l. britton and lauren gerard koch).</p> <p><b>Part 3 Contributions of Specific Genes and Markers.</b></p> <p>13 Genes and Endurance Performance (bernd wolfarth).</p> <p>14 Genes and Strength and Power Phenotypes (martine a.i. thomis).</p> <p>15 Genes and Response to Training (tuomo rankinen, mark a. sarzynski and claude bouchard).</p> <p>16 Genetic Determinants of Exercise Performance: Evidence from Transgenic and Null Mouse Models (eunhee chung and leslie a. leinwand).</p> <p>17 The <i>ACE</i> Gene and Performance (james r.a. skipworth, zudin a. puthucheary, jai rawal and hugh e. montgomery).</p> <p>18 The <i>ACTN3</i> Gene and Human Performance (daniel g. macarthur and kathryn n. north).</p> <p>19 Mitochondrial DNA Sequence Variation and Performance (shinya kuno, hirofumi zempo and haruka murakami).</p> <p>20 Genes, Exercise, and Lipid Metabolism (yohan bossé).</p> <p>21 Genes, Exercise, and Glucose and Insulin Metabolism (leonidas g. karagounis and john a. hawley).</p> <p>22 Genes, Exercise, and Cardiovascular Phenotypes (james m. hagberg).</p> <p>23 Genes, Exercise, and Protein Metabolism (mark a. tarnopolsky).</p> <p>24 The Regulation of Physical Activity by Genetic Mechanisms: Is There a Drive to Be Active? (nishan sudheera kalupahana, naima moustaid-moussa, jung han kim, brynn h. voy, david bassett, molly s. bray and j. timothy lightfoot).</p> <p>25 Genes, Exercise, and Psychological Factors (eco j.c. de geus and marleen h.m. de moor).</p> <p><b>Part 4 Systems Biology of Exercise and Training.</b></p> <p>26 A Primer on Systems Biology, as Applied to Exercise Physiology and Metabolism (james a. timmons and jorn w. helge).</p> <p>27 Systems Biology Through Time Series Data—A Strength of Muscle Remodeling (monica hubal, zuyi wang and</p> <p>eric p. hoffman).</p> <p>28 Proteomics in Exercise Training Research (dustin s. hittel).</p> <p>29 The Influence of Physical Exercise on Adult Stem Cells (fawzi kadi).</p> <p><b>Part 5 Ethical and Societal Implications.</b></p> <p>30 Genetics and Ethics in Elite Sport (sigmund loland).</p> <p>31 Genes and Talent Selection (stephen m. roth).</p> <p>32 Performance Enhancement by Gene Doping (anna baoutina).</p> <p>33 Bioethical Concerns in a Culture of Human Enhancement (andy miah).</p> <p><i>Index.</i></p>

<p><b>Professor Claude BOUCHARD</b>, PhD, Executive Director, Pennington Biomedical Research Center, Baton Rouge, Louisiana, U.S.A.</p> <p><b>Professor Eric P. HOFFMAN</b>, PhD, Director, Research Center for Genetic Medicine, Children's National Medical Center, Washington DC, U.S.A.</p>

<b>THE ENCYCLOPAEDIA OF SPORTS MEDICINE</b> <p>This latest volume in the Encyclopaedia of Sports Medicine series, published under the auspices of the International Olympic Committee, is a landmark contribution to our understanding of the role of genes and genetics in sport and other physical activities. </p> <p>The book is designed to move readers from the basic science of genomics and genetics and the regulation of gene expression to thorough, clearly-written discussions of today’s most important topics and latest research, including the genetics of complex performance phenotypes, the contributions of small animal research, family and twin studies, and ethnic comparisons.  A final section addresses how specific genes and molecular markers impact endurance, strength and power, and responsiveness to specific conditioning programs. </p> <p>Authored by scientists whose work represents the leading edge in this rapidly-evolving field,  <i>Genetic and Molecular Aspects of Sports Performance</i> is an essential new reference for exercise scientists, researchers in genetics and genomics, and sports medicine specialists.</p> <p><b>Other Titles in the Series</b></p> <p>Vol. I THE OLYMPIC BOOK OF SPORTS MEDICINE<br /> Edited by A. Dirix, H.G. Knuttgen & K. Tittel<br /> 1988, ISBN 978 0 632 01963 2 (hardback)</p> <p>Vol. II ENDURANCE IN SPORT<br /> Edited by R.J. Shephard & P-O. Åstrand<br /> 2nd edition, 2000, ISBN 978 0 632 05348 3 (hardback)</p> <p>Vol. III STRENGTH AND POWER IN SPORT<br /> Edited by P.V. Komi<br /> 2nd edition, 2003, ISBN 978 0 632 05911 9 (hardback)</p> <p>Vol. IV SPORTS INJURIES: BASIC PRINCIPLES OF PREVENTION AND CARE<br /> Edited by P.A.F.H. Renström<br /> 1993, ISBN 978 0 632 03331 7 (hardback)</p> <p>Vol. V CLINICAL PRACTICE OF SPORTS INJURY PREVENTION AND CARE<br /> Edited by P.A.F.H. Renström<br /> 1994, ISBN 978 0 632 03785 8 (hardback)</p> <p>Vol. VI THE CHILD AND ADOLESCENT ATHLETE<br /> Edited by O. Bar-Or<br /> 1996, ISBN 978 0 865 42904 8 (hardback)</p> <p>Vol. VII NUTRITION IN SPORT<br /> Edited by R.J. Maughan<br /> 2000, ISBN 978 0 632 05094 9 (hardback)</p> <p>Vol. VIII WOMEN IN SPORT<br /> Edited by B.L. Drinkwater<br /> 2000, ISBN 978 0 632 05084 0 (hardback)</p> <p>Vol. IX BIOMECHANICS IN SPORT<br /> Edited by V. Zatsiorsky<br /> 2000, ISBN 978 0 632 05392 6 (hardback)</p> <p>Vol. X REHABILITATION OF SPORTS INJURIES: SCIENTIFIC BASIS<br /> Edited by W.R. Frontera<br /> 2003, ISBN 978 0 632 05813 6 (hardback)</p> <p>Vol. XI THE ENDOCRINE SYSTEM IN SPORTS AND EXERCISE<br /> Edited by W.J. Kraemer & A.D. Rogol<br /> 2005, ISBN 978 1 4051 3017 2 (hardback)</p> <p>Vol. XII TENDINOPATHY IN ATHLETES<br /> Edited by Savio L-Y. Woo, Per A.F.H. Renstrom & Steven P. Arnoczky<br /> 2007, ISBN 978 1 4051 5670 7 (hardback)</p> <p>Vol. XIII THE YOUNG ATHLETE<br /> Edited by H. Hebestreit & O. Bar-Or<br /> 2007, ISBN 978 1 4051 5647 9 (hardback)</p> <p>Vol. XIV THE OLYMPIC TEXTBOOK OF MEDICINE IN SPORT<br /> Edited by M. Schwellnus<br /> 2008, ISBN 9781405156370 (hardback)</p> <p>Vol XV THE OLYMPICTEXTBOOK OF SCIENCE IN SPORT<br /> Edited by R. Maughan<br /> 2008, ISBN 9781405156387 (hardback)</p> <p>Vol XVI EPIDEMIOLOGY OF INJURY IN OLYMPIC SPORTS<br /> Edited by Dennis Caine, Peter Harmer and Melissa Schiff<br /> 2010. ISBN 9781405173643 (hardback)</p> <p>Vol XVII Neuromuscular Aspects of Sport Performance<br /> Edited by P. Komi<br /> 2011. ISBN 9781444334470 (hardback)</p>

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