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<p>Preface IX</p> <p><b>Volume 1</b></p> <p>1 Synthetic Biology: Implications and Uses 1<br /><i>Sanjay Vashee, Mikkel A. Algire, Michael G. Montague, and Michele S. Garfynkel</i></p> <p><b>Part I Biological Basis 33</b></p> <p>2 The Emergence of the First Cells 35<br /><i>Antoine Danchin</i></p> <p>3 Regulation of Gene Expression 61<br /><i>Anil Kumar, Sarika Garg and Neha Garg</i></p> <p>4 Interactome 121<br /><i>Teresa M. Przytycka and Dong-Yeon Cho</i></p> <p>5 Microbiomes 153<br /><i>Ramana Madupu, Yu-Hui Rogers, Doug Rusch, Jason Miller, Konstantinos Krampis, and Karen E. Nelson</i></p> <p><b>Part II Modeling 179</b></p> <p>6 Dynamics of Biomolecular Networks 181<br />Emanuele Cozzo, Joaquín Sanz, and Yamir Moreno</p> <p>7 E-Cell: Computer Simulation of the Cell 211<br /><i>Pawan K. Dhar, Kouichi Takahashi, Yoichi Nakayama, and Masaru Tomita</i></p> <p>8 SynBioSS Designer Modeling Suite 229<br /><i>Konstantinos Biliouris, Emma Weeding, and Yiannis N. Kaznessis</i></p> <p><b>Part III Modular Parts and Circuits 247</b></p> <p>9 Synthetic Gene Circuits 249<br /><i>Barbara Jusiak, Ramiz Daniel, Fahim Farzadfard, Lior Nissim, Oliver Purcell, Jacob Rubens and Timothy K. Lu</i></p> <p>10 DNA Origami Nanorobots 305<br /><i>Ido Bachelet</i></p> <p>11 RNAi Synthetic Logic Circuits for Sensing, Information Processing, and Actuation 333<br /><i>Zhen Xie, Liliana Wroblewska, and Ron Weiss</i></p> <p>12 Synthetic Hybrid Biosensors 357<br /><i>Apoorv Shanker, Kangwon Lee, and Jinsang Kim</i></p> <p>13 Synthetic Biology in Metabolic Engineering: From Complex Biochemical Pathways to Compartmentalized Metabolic Processes–a Vitamin Connection 393<br /><i>Evelyne Deery, Stefanie Frank, Andrew Lawrence, Simon Moore, Susanne Schroeder, and Martin J. Warren</i></p> <p><b>Volume 2</b></p> <p><b>Part IV Synthetic Genomes 441</b></p> <p>14 The Minimal Gene-Set Machinery 443<br /><i>Rosario Gil</i></p> <p>15 Production of Mitochondrial Genome and Chromosomal DNA Segments Highly Engineered for Use in Mouse Genetics by a Bacillus subtilis-Based BGM Vector System 479<br /><i>Mitsuhiro Itaya</i></p> <p>16 Synthetic Genetic Polymers Functioning to Store and Propagate Information by Genetic Alphabet Expansion 505<br /><i>Ichiro Hirao</i></p> <p><b>Part V Diseases and Therapeutics 521</b></p> <p>17 Synthetic Biology Approaches for Regenerative Medicine 523<br /><i>Elise Cachat, Kim C. Martin, and Jamie A. Davies</i></p> <p>18 The Synthetic Biology Approach to Stem Cells and Regenerative Medicine 541<br /><i>Boon Chin Heng, and Martin Fussenegger</i></p> <p>19 Synthetic Biology Approaches to Cell Therapy 559<br /><i>Sung-Ho Paek and Warren C. Ruder</i></p> <p>20 Synthetic Biology Approaches for Vaccine Development 589<br /><i>Sam H. Shen, Bruce Futcher, Chen Yang, and Eckard Wimmer</i></p> <p><b>Part VI Chemicals Production 617</b></p> <p>21 Metabolic Engineering for the Production of Diols 619<br /><i>Katarzyna Leja, Dorota Samul, Piotr Kubiak, Agnieszka Drozdzynska, Alicja Kósmider, Wojciech Juzwa, Mariusz Lesiecki, and Katarzyna Czaczyk</i></p> <p>22 Synthetic Biology in Biofuels Production 665<br /><i>Rahul Singh, Anu Jose Mattam, Pavan Jutur, and Syed Shams Yazdani</i></p> <p>23 Synthetic Biology of Antibiotic Production 699<br /><i>Eriko Takano and Rainer Breitling</i></p> <p>Index 723</p>

<p><b>Robert A. Meyers</b> obtained his Ph.D. in Chemistry at the University of California at Los Angeles. He was a post-doctoral fellow at the California Institute of Technology and has more than 17 patents, 50 technical papers and 12 books to his name. As Editor-in-Chief he conceived and edited several ambitious multivolume reference works, e.g. the <i>Encyclopedia of Analytical Chemistry</i> (Wiley), the <i>Encyclopedia of Molecular Biology and Molecular Medicine</i> (Wiley-VCH) and the <i>Encyclopedia of Physical Science and Technology</i> (Academic Press).</p>

These two volumes contain a selection of updated articles from the acclaimed Meyers Encyclopedia of Molecular Cell Biology and Molecular Medicine, the most authoritative resource in cell and molecular biology, combined with new articles by "founding fathers" in the field. The work is divided into six sections: <br> <br> - Biological Basis<br> - Modeling<br> - Modular Parts and Circuits<br> - Synthetic Genomes<br> - Diseases and Therapeutics <br> - Chemicals Production <br> <br> Ideally suited as advanced reading for students and postdocs, and with all current research trends covered by an impressive number of leading figures in the field, this is the first choice reference for research institutions.<br>

SG