Edited by a leading authority in the field, the first book on this important and emerging topic provides an overview of the latest trends in sequence-controlled polymers. Following a brief introduction, the book goes on to discuss various synthetic approaches to sequence-controlled and biological polymers, including genetic polymers, peptide polymers and biohybrids, as well as single-chain nanoparticles. Moreover, different polymerization techniques, such as anionic and cationic as well as radical chain growth mechanism, are explained, before concluding with a look at the future for sequence-controlled polymers. With its unique coverage of this interdisciplinary field, the text will prove invaluable to polymer and environmental chemists, as well as biochemists and bioengineers.
Introduction to Sequence-Controlled Polymers Chemical Synthesis of Genetic Polymers Synthesis of Sequence-Controlled Polymers by Genetic Engineering Synthesis of Peptide-Polymer Bio-Hybrids Synthesis of Peptidomimetics and Peptoids Iterative Synthesis of Non-Natural Polymers Synthesis of Sequence-Defined Foldamers Folding of Sequence-Defined Polymers into Single-Chain Nanoparticles Sequence-Control in Chain-Growth Ionic Polymerizations Sequence-Control in Chain-Growth Radical Polymerizations Sequence-Control in Step-Growth Polymerizations Synthesis of Multiblock Copolymers Properties of Sequence-Controlled Polymers Sequencing of Non-Natural Polymers
Dr. Jean-Francois Lutz is CNRS research director, deputy director of the Institut Charles Sadron and head of the Precision Macromolecular Chemistry group in Strasbourg, France. He obtained his PhD from the University of Montpellier II, France, in 2000 and his habilitation degree from the University of Potsdam, Germany, in 2009. Before joining the CNRS, he subsequently was a post-doctoral fellow in the group of Krzysztof Matyjaszewski at Carnegie Mellon University, USA (2001-2003) and group leader Nanotechnology for Life Science at the Fraunhofer Institute for Applied Polymer Research in Potsdam (2003-2010). He received in 2008 the prize of the polymer division of the French Chemical Society. He is also an European Research Council (ERC) laureate since 2010 through successive starting (StG 2010) and proofs of concept (PoC 2015) grants. His current research interests include the synthesis of sequence-controlled polymers, single-chain technologies and the preparation of information-containing macromolecules. He is author of more than 150 publications.