Details

Schizophrenia


Schizophrenia


3. Aufl.

von: Daniel R. Weinberger, Paul Harrison

173,99 €

Verlag: Wiley-Blackwell
Format: PDF
Veröffentl.: 07.12.2010
ISBN/EAN: 9781444327304
Sprache: englisch
Anzahl Seiten: 736

DRM-geschütztes eBook, Sie benötigen z.B. Adobe Digital Editions und eine Adobe ID zum Lesen.

Beschreibungen

Schizophrenia is one of the most complex and disabling diseases to affect mankind.   Relatively little is known about its nature and its origins, and available treatments are inadequate for most patients. As a result, there are inevitable controversies about what causes it, how to diagnose it, and how best to treat it.   However, in the past decade, there has been an explosion of new research, with dramatic discoveries involving genetic etiology and epidemiological risk factors.  There has also been a catalog of new drugs coming to market, and controversy about the relative advantages and disadvantages of newer compared with older therapies.   In addition, developing technologies in genomics, molecular biology and neuroimaging provide streams of new information. <p>This book represents a definitive, essential, and up-to-date reference text on schizophrenia. It extensively and critically digests and clarifies recent advances and places them within a clinical context.  The Editors (one American and one British), highly respected clinical psychiatrists and researchers and acknowledged experts on schizophrenia, have again assembled an outstanding group of contributors from the USA, UK, Europe and Australia, It will be of value to practising psychiatrists and to trainees, as well as to clinical and neuroscience researchers interested in keeping up with this field or coming into it.</p> <p>The book consists of four sections:   descriptive aspects, biological aspects, physical treatments, and psychological and social aspects.   It reviews the theoretical controversies over symptomatology, classification and aetiology (particularly pertinent as DSM-V is being developed), the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. It describes a variety of approaches to integrating the vast research data about schizophrenia, including neurodevelopmental, genetic, pharmacological, brain imaging and psychological findings. The biological treatment section reviews the comparative efficacy of various drugs, the management of drug-resistant patients and both neurological and metabolic complications. The final section looks at psychological therapies, social outcomes, and the economics of schizophrenia. </p> <p><b>Highly Commended in the Psychiatry section of the 2012 BMA Book Awards.</b></p>
<p>Contributors vii</p> <p>Editor’s Note xi</p> <p>Preface to the 3 Rd Edition xii</p> <p>Preface to the First Edition xiii</p> <p><b>Part 1 Descriptive Aspects 1</b></p> <p>1 Concept of schizophrenia: past present and future 3<br /> <i>Nancy C. Andreasen</i></p> <p>2 The schizophrenia construct: symptomatic presentation 9<br /> <i>Celso Arango and William T. Carpenter</i></p> <p>3 Child and adolescent schizophrenia 24<br /> <i>Chris Hollis and Judith Rapoport</i></p> <p>4 Late-onset schizophrenia 47<br /> <i>Robert Howard and Dilip Jeste</i></p> <p>5 The schizophrenia spectrum personality disorders 62<br /> <i>Eran Chemerinski and Larry J. Siever</i></p> <p>6 The prodrome of schizophrenia 91<br /> <i>Jean Addington and Shôn W. Lewis</i></p> <p>7 Course and outcome 104<br /> <i>Wolfram an der Heiden and Heinz Häfner</i></p> <p>8 Neurocognitive impairments in schizophrenia: their character and role in symptom formation 142<br /> <i>Terry E. Goldberg Anthony David and James. M. Gold</i></p> <p><b>Part 2 Biological Aspects 163</b></p> <p>9 The secondary schizophrenias 165<br /> <i>Thomas M. Hyde and Maria A. Ron</i></p> <p>10 Schizophrenia: the epidemiological horizon 185<br /> <i>Assen Jablensky James B. Kirkbride and Peter B. Jones</i></p> <p>11 Environmental risk factors for schizophrenia 226<br /> <i>John J. McGrath and Robin M. Murray</i></p> <p>12 Classical genetic studies of schizophrenia 245<br /> <i>Brien Riley and Kenneth S. Kendler</i></p> <p>13 Genetic associations in schizophrenia 269<br /> <i>Michael C. O’Donovan and Michael J. Owen</i></p> <p>14 Intermediate phenotypes in genetic studies of schizophrenia 289<br /> <i>Michael F. Egan and Tyrone D. Cannon</i></p> <p>15 Electrophysiology of schizophrenia 311<br /> <i>Georg Winterer and Robert W. McCarley</i></p> <p>16 Structural brain imaging in schizophrenia and related populations 334<br /> <i>Stephen M. Lawrie and Christos Pantelis</i></p> <p>17 Functional brain imaging in schizophrenia 353<br /> <i>Andreas Meyer-Lindenberg and Edward T. Bullmore</i></p> <p>18 Neuropathology of schizophrenia 372<br /> <i>Paul J. Harrison David A. Lewis and Joel E. Kleinman</i></p> <p>19 Neurodevelopmental origins of schizophrenia 393<br /> <i>Daniel R. Weinberger and Pat Levitt</i></p> <p>20 Dopamine and schizophrenia 413<br /> <i>Anissa Abi-Dargham and Anthony A. Grace</i></p> <p>21 Contributions of glutamate and GABA systems to the neurobiology and treatment of schizophrenia 433<br /> <i>John H. Krystal and Bita Moghaddam</i></p> <p>22 Animal models of schizophrenia 462<br /> <i>Barbara K. Lipska and Joseph A. Gogos</i></p> <p><b>Part 3 Physical Treatments 483</b></p> <p>23 Pharmacology and neuroscience of antipsychotic drugs 485<br /> <i>John L. Waddington Colm M.P. O’Tuathaigh and Gary J. Remington</i></p> <p>24 Principles of pharmacological treatment in schizophrenia 515<br /> <i>Thomas R.E. Barnes and Stephen R. Marder</i></p> <p>25 Comparative efficacy and effectiveness in the drug treatment of schizophrenia 525<br /> <i>John R. Geddes T. Scott Stroup and Jeffrey A. Lieberman</i></p> <p>26 Approaches to treatment-resistant patients 540<br /> <i>Stephan Leucht Christoph U. Correll and John M. Kane</i></p> <p>27 Neurological complications of antipsychotic drugs 561<br /> <i>Peter M. Haddad and Venkata S. Mattay</i></p> <p>28 Metabolic adverse effects associated with antipsychotic medications 577<br /> <i>John W. Newcomer and Stefan Leucht</i></p> <p><b>Part 4 Psychosocial Aspects 599</b></p> <p>29 Schizophrenia and psychosocial stresses 601<br /> <i>Paul E. Bebbington and Elizabeth Kuipers</i></p> <p>30 Mental health services for patients with schizophrenia 625<br /> <i>Tom Burns and Bob Drake</i></p> <p>31 Societal outcomes in schizophrenia 644<br /> <i>Iain Kooyman and Elizabeth Walsh</i></p> <p>32 Psychological treatment of psychosis 666<br /> <i>Gillian Haddock and Will Spaulding</i></p> <p>33 Economics of the treatment of schizophrenia 687<br /> <i>Nancy H. Covell Susan M. Essock and Linda K. Frisman</i></p> <p>Index 701</p> <p>Colour plates are found facing page 338</p>
<p>"I thoroughly recommend this book as a well-integrated collection of thoughtful and up-to-date expositions on every aspect of schizophrenia, by some of the best scientists in the field. " (<i>Psychological Medicine, 2012</i>)<br /> <br /> “It will be of valuable to practising psychiatrists and to trainees, as well as to the clinical and neuroscience researchers interested in keeping up with this field or coming into it.”  (<i>Buchtipps</i>,  September 2012)</p> <p>"The contributing authors and editors constitute an international list of '"who's who" in contemporary schizophrenia research. Overall this book represents a highly systematic, comprehensive, scholarly, and critical appraisal of a core component of modern psychiatry and a major publice health challenge. It ably summarizes and evalutates efforts to better understand the nature, diagnosis, biology, psychology, sociology and clinical treatment of the group of largely "nonaffective" psychotic disorders currently considered within the nosological domain of schizophrenia. As such, it is an essential volume for students, researchers, clinicians, and administrators interested in improved understanding and care of persons diagnosed with psychotic disorders." (<i>Journal of Clinical Psychiatry, 2012</i>)</p>
<b>Daniel R. Weinberger</b>, Director: Genes, Cognition and Psychosis Program, National Institute of Mental  Health, National Institute of Health, Bethesda, USA<br /> <br /> <p><b>Paul J. Harrison</b>, University Department of Psychiatry, Warneford Hospital, Oxford, UK</p>
Schizophrenia is one of the most complex and disabling diseases to affect mankind.   Relatively little is known about its nature and its origins, and available treatments are inadequate for most patients. As a result, there are inevitable controversies about what causes it, how to diagnose it, and how best to treat it.   However, in the past decade, there has been an explosion of new research, with dramatic discoveries involving genetic etiology and epidemiological risk factors.  There has also been a catalog of new drugs coming to market, and controversy about the relative advantages and disadvantages of newer compared with older therapies.   In addition, developing technologies in genomics, molecular biology and neuroimaging provide streams of new information. <p>This book represents a definitive, essential, and up-to-date reference text on schizophrenia. It extensively and critically digests and clarifies recent advances and places them within a clinical context.  The Editors (one American and one British), highly respected clinical psychiatrists and researchers and acknowledged experts on schizophrenia, have again assembled an outstanding group of contributors from the USA, UK, Europe and Australia, It will be of value to practising psychiatrists and to trainees, as well as to clinical and neuroscience researchers interested in keeping up with this field or coming into it.</p> <p>The book consists of four sections:   descriptive aspects, biological aspects, physical treatments, and psychological and social aspects.   It reviews the theoretical controversies over symptomatology, classification and aetiology (particularly pertinent as DSM-V is being developed), the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. It describes a variety of approaches to integrating the vast research data about schizophrenia, including neurodevelopmental, genetic, pharmacological, brain imaging and psychological findings. The biological treatment section reviews the comparative efficacy of various drugs, the management of drug-resistant patients and both neurological and metabolic complications. The final section looks at psychological therapies, social outcomes, and the economics of schizophrenia. </p>

Diese Produkte könnten Sie auch interessieren:

Biomedical Imaging
Biomedical Imaging
von: Reiner Salzer
PDF ebook
120,99 €
Clinical Reasoning in Occupational Therapy
Clinical Reasoning in Occupational Therapy
von: Linda Robertson
PDF ebook
38,99 €
Clinical Reasoning in Occupational Therapy
Clinical Reasoning in Occupational Therapy
von: Linda Robertson
EPUB ebook
38,99 €