The most important and reliable resource for treating diseases of the liver For more than 55 years, "Schiff" has been acclaimed as the most outstanding liver book in the world. This new 12th edition brings the field completely up to date and includes a companion website that features a wide-variety of accessory materials. The text is evidence-based to offer hepatologists and gastroenterologists treating patients with liver disease a comprehensive and essential resource. The text highlights clinical practice and covers anatomy, pathology, testing, imaging, and the effects of liver disease on other organs. The book is written in clear and accessible terms and key features include: Treatment guidelines and management algorithms for every disease Full-color attractive design throughout the text Informative section overviews for each section Concise key concepts box in every chapter A full liver transplant section This 12th edition is thoroughly revised with the latest clinical information. The new edition offers: Information on acute and chronic liver failure and infections in cirrhosis Over 100 MCQs Downloads for Powerpoint™ making the content ideal for presentations Schiff's Diseases of the Liver is designed to be a first-stop reference for dealing with today’s demanding clinical situations.
Contributors Foreword Preface About the CompanionWebsite Part I Overview: Clinical Fundamentals of Hepatology 1 History Taking and Physical Examination for the Patient with Liver DiseaseEsperance A. Schaefer and Lawrence S. Friedman 2 Laboratory Tests, Noninvasive Markers of Fibrosis, Liver Biopsy, and LaparoscopyMichael P. Curry and Lennox J. Jeffers 3 Noninvasive and Invasive Imaging of the Liver and Biliary TractKoushik K. Das, Matthew A.Morgan, and Gregory G. Ginsberg Part II General Considerations 4 Physioanatomic ConsiderationsIan R. Wanless 5 Bilirubin Metabolism and JaundiceAllan W. Wolkoff and Paul D. Berk 6 Hepatic HistopathologyZachary D. Goodman 7 Mechanisms of Liver InjuryHarmeet Malhi and Gregory J. Gores 8 Hepatic Manifestations of Systemic DisordersStuart C. Gordon and Humberto C. Gonzalez 9 The Liver in PregnancyNancy Reau and Yannick Bacq Part III Consequences of Liver Disease 10 Hepatic FibrosisScott L. Friedman 11 Preoperative Evaluation of the Patient with Liver DiseasePatrick S. Kamath and Mark T. Keegan 12 Management of Portal HypertensionGuadalupe Garcia-Tsao and Juan G. Abraldes 13 Renal Complications of Liver Disease and the Hepatorenal Syndrome, 33Xingxing S. Cheng and W. Ray Kim 14 Pulmonary Manifestations of Liver DiseaseMichael B. Fallon and Anil Seetharam 15 Ascites and Spontaneous Bacterial PeritonitisVicente Arroyo and Javier Fern´andez 16 Hepatic EncephalopathyChathur Acharya and Jasmohan S. Bajaj 17 Acute Liver FailureRobert J. Fontana and Khurram Bari 18 Acute-on-Chronic Liver FailureFlorence Wong 19 Malnutrition and Liver DiseaseCraig McClain, Irina Kirpich, and Laura Smart Part IV Cholestatic Disorders 20 Primary Sclerosing CholangitisJohn M. Vierling 21 Primary Biliary CholangitisCynthia Levy, Andres F. Carrion, and Marlyn J. Mayo 22 Autoimmune HepatitisGideon M. Hirschfield and Gwilym J. Webb Part V Viral Hepatitis 23 Hepatitis A and EKenneth E. Sherman and Shyam Kottilil 24 Hepatitis B and DMarc G. Ghany and Naveen Gara 25 Hepatitis CMichael W. Fried, Jama M. Darling, and Stanley M. Lemon Part VI Alcohol- and Drug-induced Liver Disease 26 Alcoholic Liver DiseaseMack C. Mitchell and Gyongyi Szabo 27 Drug-induced Hepatotoxicity, 740Dominique Larrey, Jose Ursic-Bedoya, and Lucy Meunier 28 Mechanisms of Drug-induced Liver InjuryPaul B. Watkins and Merrie Mosedale Part VII Genetic and Metabolic Disease 29 Wilson DiseaseMichael L. Schilsky and Aftab Ala 30 Hemochromatosis and Iron Storage DisordersKris V. Kowdley and Priya Handa 31 Alpha-1 Antitrypsin DeficiencyDavid H. Perlmutter 32 Nonalcoholic Fatty Liver DiseaseCurtis K. Argo, Zachary H. Henry, and Stephen H. Caldwell Part VIII Vascular Diseases of the Liver 33 Vascular Liver DiseaseDominique-Charles Valla 34 The Liver in Circulatory FailureSantiago J. Munoz, Hanisha R. Manickavasagan, and Idean Amirjazil Part IX Benign and Malignant Tumors; Cystic Disorders 35 Benign Tumors, Nodules, and Cystic Diseases of the LiverJulien Calderaro and Jessica Zucman-Rossi 36 Hepatocellular CarcinomaMaddie Kubiliun and Jorge A. Marrero 37 Surgical Options in Liver CancersGarrett R. Roll and John Paul Roberts Part X Infectious and Granulomatous Disease 38 Amoebic and Pyogenic Liver AbscessesMarco A. Olivera-Mart´ýnez and David Kershenobich 39 Parasitic DiseasesMichael A. Dunn 40 Granulomas of the LiverJames H. Lewis Part XI Elements of Liver Transplantation 41 Selection of Candidates and Timing of Liver TransplantationMeaghan Phipps, Alyson N. Fox, and Robert S. Brown Jr. 42 Immunosuppression: The Global PictureCaroline C. Jadlowiec, Timucin Taner, and Russell H. Wiesner 43 The First Six Months Following Liver TransplantationK. Rajender Reddy and Manuel Mendizabal 44 Long-term Management of the Liver Transplant PatientTimothy M. McCashland 45 The Liver Transplant ProcedureBijan Eghtesad, Koji Hashimoto, and John Fung 46 Recurrent Disease Following Liver TransplantationHaripriya Maddur and Josh Levitsky 47 The Role of RetransplantationPeter L. Abt and Kim M. Olthoff 48 Controversies in Liver TransplantationJames F. Trotter Index
About the Editors EUGENE R. SCHIFF MD, MACP, FRCP, MACG, FAASLD is Professor of Medicine, University of Miami Miller School of Medicine, and Director, Schiff Center for Liver Diseases, Miami, USA. WILLIS C. MADDREY MD, MACP, FRCP, FAASLD is Professor of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA. K. RAJENDER REDDY MD, FAASLD is Ruimy Family President's Distinguished Professor of Medicine, Director of Hepatology, and Medical Director of Liver Transplantation, University of Pennsylvania, Philadelphia, USA.
The most important and reliable resource for treating diseases of the liver For more than 55 years, “Schiff” has been acclaimed as the most outstanding liver book in the world. This new 12th edition brings the field completely up to date and includes a companion website. The text is evidence-based to offer hepatologists and gastroenterologists treating patients with liver disease a comprehensive and essential resource. The text highlights clinical practice and covers anatomy, pathology, testing, imaging, and the effects of liver disease on other organs. The book is written in clear and accessible terms and key features include: Treatment guidelines and management algorithms for every disease Attractive full-color design throughout the text Concise key concepts box in every chapter A full liver transplant section This 12th edition is thoroughly revised with the latest clinical information. The new edition also offers: Information on acute and chronic liver failure and infections in cirrhosis Over 100 MCQs and PowerPoints of all figures from the print book on a companion website Schiff’s Diseases of the Liver is designed to be a first-stop reference for dealing with today’s demanding clinical situations.
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