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Clinical Anaesthesia

Lecture Notes

Matthew Gwinnutt

MB ChB (Hons) FRCA
Specialist Trainee in Anaesthesia
Health Education North West
Mersey School of Anaesthesia
UK

Carl Gwinnutt

MB BS MRCS LRCP FRCA
Emeritus Consultant
Salford Royal Hospitals NHS Foundation Trust
Salford, UK

 

Fifth Edition

 

 

 

 

 

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Contributors

 

Russell Perkins FRCA
Consultant Paediatric Anaesthetist
Royal Manchester Children’s Hospital
Manchester, UK

Justin Turner FRCA
Consultant in Anaesthesia and Pain Management
Salford Royal Hospitals NHS Foundation Trust
Salford, UK

Preface

It is only four years since the last edition of this book, but changes continue apace and the time had come to ensure that Lecture Notes, Clinical Anaesthesia reflected these changes and also responded to the feedback received around the previous edition. The first major change is the new Chapter 1, ‘An introduction to anaesthesia’. We hope you will take the time to have a look at this, even if only briefly, as we have tried to provide an insight into how the specialty has developed and where it is heading. It is estimated that around 70% of all hospital patients encounter an anaesthetist at some point during their admission, hardly surprising when we consider how broad the scope of the specialty of anaesthesia has become and the numerous professionals working together as part of the team. Therefore, we have approached the task of writing of this edition with the team in mind, and hope that it will be useful not only for medical students but also for trainees in anaesthesia and other acute specialties, trainee physician’s assistants in anaesthesia, operating department practitioners and recovery nurses.

As would be expected, the content has been fully updated to reflect areas where there have been changes in clinical practice, new guidelines and new equipment or drugs. We have increased coverage of the perioperative management of the overweight and obese patient to reflect the increasing frequency with which this group of patients is encountered and, in response to numerous requests, we have for the first time included an introduction to some basic aspects of paediatric anaesthesia. Other new topics include an outline of enhanced recovery after surgery (ERAS) and the importance of anaesthetists’ non‐technical skills (NTS). Given the likely future expansion of anaesthetists into the developing field of perioperative care, we felt it appropriate to keep and expand slightly the chapter detailing the recognition and management of some of the more common perioperative medical emergencies.

Apart from updating the contents, there are two key changes in this edition compared to previous ones. Firstly, to help you take a structured approach to learning about anaesthesia, we have included a series of objectives at the start of each chapter. These are divided into two sections: firstly, the knowledge you should aim to acquire by reading each chapter, and secondly, an indication of the skills that we feel are important and are based upon the former. We hope this will give you a clearer idea of what you should try and achieve during an anaesthetic attachment. For those of you using this book who are not medical students, we feel these learning objectives are equally relevant and achievable.

The second change is an attempt to encourage you to use the vast resources available via the internet. The potential problem with this approach is that there is little quality control over what is available. Therefore, we have only included links to web sites we know, have checked and believe are reliable. For those of you using a hard copy of the book, interesting and useful web sites are numbered within the text, for example [2.2], and the web address is listed in the ‘Further information’ section at the end of the chapter. For those of you using the e‐book, the numbers within the text are hyperlinked directly to an organization’s web site or a specific article. We hope you will use this and feel free to feed back your thoughts and comments.

Finally, we close by repeating the same message as in previous editions – we hope that you will enjoy this book but, more importantly, that it helps you provide better care for your patients. If it has, tell your friends, if it hasn’t, tell us! We hope that it is improving each time, but it still is and will always remain ‘work in progress’.

Acknowledgements

We would like to thank Deltex Medical for Figures 3.16 and 3.17. Figure 3.7 is from McGuire and Younger, 2010 (see Further information in Chapter 3), with permission of Oxford University Press on behalf of the British Journal of Anaesthesia.

Figure 5.12 is reproduced with permission of Dr P. Ross and I am grateful to Dr J. Corcoran for his help and advice with transversus abdominis plane blocks and Figure 6.1.

Figures 9.8, 9.9, 9.10 and 9.11 are reproduced with kind permission from the Resuscitation Council (UK) and Dr Michael Scott.

Thanks are due to the Difficult Airway Society for Figure 5.9, the National Tracheostomy Safety Project for Figures 9.3 and 9.4, and to Dr David Pitcher for his guidance on ‘Decisions about cardiopulmonary resuscitation’.

We would also like to express our gratitude to Dr Richard Morgan, Professor Gary Smith and Dr Jas Soar for their contributions to the previous editions, some of which by necessity have been included in this edition.

Abbreviations

AAGBI
Association of Anaesthetists of Great Britain and Ireland
ABG
arterial blood gas
ABW
adjusted body weight
ACD‐A
anticoagulant citrate dextrose solution A
ACE‐I
angiotensin converting enzyme inhibitor
ACS
acute coronary syndrome
ADH
antidiuretic hormone
AIM
Acute Illness Management
AKI
acute kidney injury
ALERT
Acute Life‐threatening Event Recognition and Treatment
ALS
Advanced Life Support
AMI
acute myocardial infarction
ANTT
antiseptic no‐touch technique
APL
adjustable pressure limiting
APLS
Advanced Paediatric Life Support
ARDS
acute respiratory distress syndrome
ASA
American Society of Anesthesiologists
AT
anaerobic threshold
ATN
acute tubular necrosis
AV
atrioventricular
BIS
bispectral index
BMI
body mass index
BNF
British National Formulary
BiPAP
bilevel positive airway pressure
BP
blood pressure
BTS
British Thoracic Society
CAP
community‐acquired pneumonia
CCrISP
Care of the Critically Ill Surgical Patient
CCU
coronary care unit
CEPOD
Confidential Enquiry into Perioperative Death
CNS
central nervous system
CO2
carbon dioxide
COPD
chronic obstructive pulmonary disease
COX
cyclo‐oxygenase
CPAP
continuous positive airway pressure
CPR
cardiopulmonary resuscitation
CPX
cardiopulmonary exercise
CRP
C‐reactive protein
CRT
capillary refill time
CSF
cerebrospinal fluid
CT
computed tomography
CTPA
computed tomography pulmonary angiography
CVC
central venous catheter
CVP
central venous pressure
CVS
cardiovascular system
CXR
chest X‐ray
DAS
Difficult Airway Society
DBP
diastolic blood pressure
DBS
double‐burst simulation
DNACPR
do not attempt cardiopulmonary resuscitation
DS
degrees of substitution
DVT
deep venous thrombosis
ECF
extracellular fluid
ECG
electrocardiogram
EEG
electroencephalograph
EMLA
eutectic mixture of local anaesthetics
ENT
ear, nose and throat
EPLS
European Paediatric Life Support
ETC
European Trauma Course
ETT
exercise tolerance test
EWS
Early Warning Score
FAST
focused assessment with sonography in trauma
FBC
full blood count
FEEL
focused echocardiography in emergency life support
FEV1
forced expiratory volume in 1 second
FFP
fresh frozen plasma
FICM
Faculty of Intensive Care Medicine
FiO2
fractional inspired oxygen concentration
FRC
functional residual capacity
FRCA
Fellow of the Royal College of Anaesthetists
FVC
forced vital capacity
GCS
Glasgow Coma Scale
GFR
glomerular filtration rate
GI
gastrointestinal
GTN
glyceryl trinitrate
HAFOE
high‐airflow oxygen enrichment
HAP
hospital‐acquired pneumonia
Hb
haemoglobin
HbA1c
glycosylated haemoglobin
HDU
high‐dependency unit
HIV
human immunodeficiency virus
HR
heart rate
HRT
hormone replacement therapy
5‐HT
5‐hydroxytryptamine
HTLV
human T‐cell lymphotrophic virus
IBW
ideal body weight
ICF
intracellular fluid
ICM
intensive care medicine
ICP
intracranial pressure
ICU
intensive care unit
I:E ratio
inspiratory:expiratory ratio
ILMA
intubating LMA
IM
intramuscular
INR
international normalized ratio
IPPV
intermittent positive pressure ventilation
IR
immediate release
ITU
intensive therapy unit
IV
intravenous
IVC
inferior vena cava
IVRA
intravenous regional anaesthesia
JVP
jugular venous pressure
K+
potassium ions
kPa
kilopascals
LA
local anaesthetic
LBBB
left bundle branch block
LBW
lean body weight
LED
light‐emitting diode
LFT
liver function test
LMA
laryngeal mask airway
LMWH
low molecular weight heparin
LP
lumbar puncture
LSD
lysergic acid diethylamide
LVF
left ventricular failure
MAC
minimum alveolar concentration
MAP
mean arterial pressure
MET
metabolic equivalent; medical emergency team
MH
malignant hyperpyrexia
MHRA
Medicines and Healthcare products Regulatory Agency
MI
myocardial infarction
MODS
multiple organ dysfunction syndrome
MR
modified release
MRI
magnetic resonance imaging
Na+
sodium ions
NCEPOD
National Confidential Enquiry into Patient Outcome and Death
NEWS
National Early Warning Score
NIBP
non‐invasive blood pressure
NICE
National Institute for Health and Care Excellence
NMDA
N‐methyl‐D‐aspartate
N2O
nitrous oxide
NPSA
National Patient Safety Agency
NSAID
non‐steroidal anti‐inflammatory drug
NSTEMI
non‐ST segment elevation myocardial infarction
NYHA
New York Heart Association
OCP
oral contraceptive pill
ODP
operating department practitioner
OHS
obesity hypoventilation syndrome
OLV
one‐lung ventilation
OSA
obstructive sleep apnoea
OSAHS
obstructive sleep apnoea and hypopnoea syndrome
OS‐MRS
Obesity Surgery Mortality Risk Score
OTC
over the counter
PA(A)
physician’s assistant (anaesthesia)
PaCO2
arterial partial pressure of carbon dioxide
PACU
postanaesthesia care unit
PCA
patient‐controlled anaesthesia
PCI
percutaneous coronary intervention
PCV
pressure‐controlled ventilation
PDPH
postdural puncture headache
PE
pulmonary embolism
PEA
pulseless electrical activity
PEEP
positive end expiratory pressure
PEF
peak expiratory flow
PEFR
peak expiratory flow rate
PMGV
piped medical gas and vacuum system
PaO2
arterial partial pressure of oxygen
POCT
point of care testing
PONV
postoperative nausea and vomiting
PPCI
primary percutaneous coronary intervention
PPI
proton pump inhibitor
psi
pounds per square inch
PSV
pressure support ventilation
PT
prothrombin time
pVT
pulseless ventricular tachycardia
RBBB
right bundle branch block
ROSC
return of spontaneous circulation
RRT
renal replacement therapy
RSI
rapid‐sequence induction
RSVP
Reason, Story, Vital signs, Plan
SBAR
Situation, Background, Assessment, Response
SBP
systolic blood pressure
SGA
supraglottic airway
SIRS
systemic inflammatory response syndrome
SOBA
Society for Obesity and Bariatric Anaesthesia
SpO2
peripheral oxygen saturation
STEMI
ST segment elevation myocardial infarction
SVC
superior vena cava
TAP
transversus abdominis plane
TBW
total body weight
TCI
target‐controlled infusion
TIVA
total intravenous anaesthesia
TOF
train‐of‐four
TTE
transthoracic echocardiography
U&E
urea and electrolytes
VCO2
carbon dioxide production
VF
ventricular fibrillation
VIE
vacuum‐insulated evaporator
VO2
oxygen consumption
V/Q
ventilation/perfusion ratio
VT
ventricular tachycardia
VTE
venous thromboembolism
WBC
white blood cell
WHO
World Health Organization

About the companion website

Don’t forget to visit the companion website for this book:

www.lecturenoteseries.com/anaesthesia web

There you will find valuable material designed to enhance your learning, including:

  • Interactive true/false questions
  • Interactive short‐answer questions
  • A list of further reading and resources.

Scan this QR code to visit the companion website:

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