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Library of Congress Cataloging-in-Publication Data:

Shaik, Sason, 1947–
    Chemistry as a game of molecular construction : the bond-click way / Sason Shaik.
          pages cm
    Includes bibliographical references and index.
    ISBN 978-1-119-00140-9 (pbk.)
1. Chemistry–Textbooks.    I. Title.
    QD31.3.S47 2016
    540–dc23

2015024292

CONTENTS

FOREWORD

BUILDING
NOTE

PREFACE

COMMENTS TO THE TEACHERS/STUDENTS
A CONVERSATION ON THE TEXTBOOK AND ITS INTENDED READERS
REFERENCES AND NOTES

LECTURE 1 MOLECULAR BLUES

1.1 CONVERSATION ON CONTENTS OF LECTURE 1
1.2 THE UNIVERSAL ASPECT OF CHEMISTRY
1.3 LOVE, ADDICTION, PSYCHOLOGICAL BALANCE, ETC.
1.4 THE CHEMICAL MECHANISM OF NEUROTRANSMISSION
1.5 MOLECULES OF PLEASURE, WELLNESS, AND PAIR BONDING
1.6 MORE CHEMICAL CONTROL
1.7 THE CHEMICAL MATTER
1.8 MOLECULAR ARCHITECTURE AND ITS EMERGENT PROPERTIES
1.9 CHIRALITY, AND THE MAGIC BY WHICH MOLECULES RECOGNIZE OTHERS IN NATURE
1.10 OUR GENETIC CODE IS CHEMICAL
1.11 CHEMISTRY AND ITS EMERGENT EXPRESSIONS
1.12 REFERENCES AND NOTES
1.A APPENDIX
1.R RETOUCHES

LECTURE 2 THE CHEMICAL BOND AND THE LEGO PRINCIPLE

2.1 CONVERSATION ON CONTENTS OF LECTURE 2
2.2 THE PERIODIC TABLE: THE STOREHOUSE OF ATOMS
2.3 THE LEGO PRINCIPLE
2.4 THE BONDING CAPABILITY OF ATOMS AND THE LAW OF NIRVANA FOR MAIN GROUP ELEMENTS
2.5 MAKING MOLECULES USING THE AVAILABLE ATOM CONNECTIVITY AND THE LAW OF NIRVANA
2.6 THE PRINCIPLE OF CONSERVATION OF THE NUMBER OF ATOMS IN CHEMICAL REACTIONS
2.7 SUMMARY
2.8 REFERENCES
2.A APPENDIX
2.R RETOUCHES
2P PROBLEM SET

LECTURE 3 ELECTRON-DEFICIENT MOLECULES, GIANT MOLECULES, AND CONNECTIVITY OF LARGE FRAGMENTS

3.1 CONVERSATION ON CONTENTS OF LECTURE 3
3.2 ELECTRON-DEFICIENT MOLECULES
3.3 THE POWER OF MULTIPLE CONNECTIVITY: SiO₂—A GIANT MOLECULE
3.4 SiO₂ AND GLASS MAKING
3.5 GLASS MAKING FROM WATER GLASS
3.6 MUST WE WORK SO HARD TO CONSTRUCT LARGE MOLECULES?
3.7 SUMMARY
3.8 REFERENCES
3.A APPENDIX
3.R RETOUCHES
3P PROBLEM SET

LECTURE 4 CONSTRUCTING MOLECULAR WORLDS OF CARBON–HYDROGEN FROM LARGE LEGO FRAGMENTS

4.1 CONVERSATION ON CONTENTS OF LECTURE 4
4.2 MOLECULAR CHAINS INVOLVING ONLY C AND H
4.3 MOLECULAR RINGS AND CAGES MADE FROM CH₂ AND CH FRAGMENTS
4.4 MOLECULAR PLANES AND CAGES MADE FROM C FRAGMENTS
4.5 ISOMERS OF RINGS AND CAGES
4.6 INFINITY OF MOLECULAR WORLDS MADE FROM C AND H
4.7 SUMMARY
4.8 REFERENCES
4.R RETOUCHES
4P PROBLEM SET

LECTURE 5 CONSTRUCTING MOLECULAR WORLDS OF LIFE FROM LARGE LEGO FRAGMENTS

5.1 CONVERSATION ON CONTENTS OF LECTURE 5
5.2 ALCOHOLS, ALDEHYDES, KETONES, ETHERS, AND AMINES
5.3 SUMMARY
5.4 REFERENCES
5.A APPENDIX
5.R RETOUCHES
5P PROBLEM SET

LECTURE 6 ELECTRON RICHNESS, DNA AND RNA MOLECULES, AND SYNTHETIC POLYMERS

6.1 CONVERSATION ON CONTENTS OF LECTURE 6
6.2 ELECTRON RICHNESS: A DIFFERENT STATE OF NIRVANA
6.3 DNA AND RNA STRANDS
6.4 SYNTHETIC POLYMERS
6.5 SUMMARY
6.6 REFERENCES AND NOTES
6.A APPENDIX
6.R RETOUCHES
6P PROBLEM SET

LECTURE 7 THE 3D STRUCTURE OF MOLECULES, ELECTRONEGATIVITY, HYDROGEN BONDS, AND MOLECULAR ARCHITECTURE

7.1 CONVERSATION ON CONTENTS OF LECTURE 7
7.2 3D STRUCTURES OF MOLECULES
7.3 HANDEDNESS (CHIRALITY) AND ISOMERISM
7.4 EXTENSION OF THE 3D RULES TO CONFORMATIONS
7.5 THE ARCHITECTURE OF MATTER AND ITS ORIGINS
7.6 H-BONDING AND OUR GENETIC CODE
7.7 SUMMARY
7.8 REFERENCES AND NOTE
7.A APPENDIX
7.R RETOUCHES
7P PROBLEM SET

LECTURE 8 THE IONIC BOND AND IONIC MATTER

8.1 CONVERSATION ON CONTENTS OF LECTURE 8
8.2 IONIC BONDS VERSUS COVALENT BONDS
8.3 THE USE OF IONIC MATTER IN LIVING ORGANISMS
8.4 COVALENT MOLECULES THAT FORM IONS IN SOLUTION: ACIDS AND BASES
8.5 SUMMARY
8.6 REFERENCES AND NOTES
8.A APPENDIX
8.R RETOUCHES
8P PROBLEM SET

LECTURE 9 BONDING IN TRANSITION METALS, SPECTROSCOPY, AND MOLECULAR DIMENSIONS

9.1 CONVERSATION ON CONTENTS OF LECTURE 9
9.2 THE 18-ELECTRON RULE FOR TRANSITION METAL BONDING
9.3 CONSTRUCTION OF TRANSITION METAL COMPLEXES THAT OBEY THE 18e RULE
9.4 TRANSITION METAL COMPLEXES WITH 14–16e
9.5 3D SHAPES OF TRANSITION METAL COMPLEXES
9.6 BRIDGING TRANSITION METAL AND ORGANIC MOLECULES: BONDING CAPABILITIES OF FRAGMENTS OF TRANSITION METAL COMPLEXES
9.7 SUMMARY OF TRANSITION METAL COMPLEXES
9.8 SPECTROSCOPY OR HOW DO CHEMISTS “LISTEN TO MOLECULES”?
9.9 SUMMARY OF SPECTROSCOPIC METHODS
9.10 REFERENCES AND NOTES
9.A APPENDIX
9.R RETOUCHES
9P PROBLEM SET

LECTURE 10 CHEMISTRY, THE TWO-FACED JANUS—THE DAMAGE IT CAUSES VERSUS ITS IMMENSE CONTRIBUTION TO MANKIND

10.1 CONVERSATION ON CONTENTS OF LECTURE 10
10.2 TYPES OF POTENTIAL CHEMICAL DAMAGE
10.3 SUMMARY
10.4 REFERENCES AND NOTES
10.R RETOUCHES
10P PROBLEM SET

LECTURE 11 CHEMISTRY IS EVERYTHING AND EVERYTHING IS CHEMISTRY

11.1 CONVERSATION ON CONTENTS OF LECTURE 11
11.2 THE BIRTH OF CHEMISTRY IS THE NASCENCE OF MANKIND
11.3 CHEMISTRY IS EVERYTHING
11.4 THE MAGIC OF CHEMISTRY AND PATHOLOGICAL SCIENCE
11.5 THE LOVE OF CHEMISTRY
11.6 SUMMARY
11.7 REFERENCES AND NOTES
11.A APPENDIX

EPILOGUE

ANSWERS TO PROBLEM SETS

INDEX

EULA

CHEMISTRY AS A GAME OF
MOLECULAR CONSTRUCTION

The Bond-ClickWay