Cover

Table of Contents

Companion website

This book is accompanied by a website:

The website includes:

  • Over 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures
  • 300+ MCQs written to mirror the American College of Gastroenterology postgraduate course exams
  • More than 35 management protocol charts for different diseases, all fully downloadable and editable, to help clinicians tailor the management programs for different patients
  • All 850+ illustrations, available as downloadable digital files for use in scientific presentations.
Title page

This edition first published 2012 © 2012 by Blackwell Publishing Ltd

First edition published 2005, © 2005 Elsevier, Inc.

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Library of Congress Cataloging-in-Publication Data

Textbook of clinical gastroenterology and hepatology / editors, C.J. Hawkey . . . [et al.]. – 2nd ed.

p. ; cm.

 Rev. ed. of: Clinical gastroenterology and hepatology / editors, Wilfred M. Weinstein, C.J. Hawkey, Jaime Bosch. 2005.

 Includes bibliographical references and index.

 ISBN-13: 978-1-4051-9182-1 (hardcover : alk. paper)

 ISBN-10: 1-4051-9182-1 (hardcover : alk. paper)

 ISBN-13: 978-1-1183-2142-3 (epub)

 ISBN-13: 978-1-1183-2139-3 (mobi)

 I. Hawkey, C. J. II. Clinical gastroenterology and hepatology.

 [DNLM: 1. Digestive System Diseases–diagnosis. 2. Digestive System Diseases–therapy. 3. Liver Diseases–diagnosis. 4. Liver Diseases–therapy. WI 141]

 LC classification not assigned

 616.3'3–dc23

2011029724

A catalogue record for this book is available from the British Library.

Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.

List of contributors

Juan G. Abraldes MD, MMSc

Hepatic Hemodynamic Laboratory

Liver Unit, Institut de Malalties Digestives i Metaboliques

University of Barcelona, CIBERehd

Barcelona, Spain

Ahmed Abu Shanab MD

Alimentary Pharmabiotic Centre

Department of Medicine

University College Cork

Cork, Ireland

Austin G. Acheson MB, Bch, MD, FRCS

Division of GI Surgery

Nottingham University Hospitals

Nottingham, UK

Feras T. Alissa MBBS, MD

Department of Pediatrics

University of Pittsburgh School of Medicine

Children’s Hospital of Pittsburgh of UPMC

Pittsburgh, PA, USA

Majid Almadi MBBS, FRCPC, MSc (Epi)

Department of Gastroenterology

King Khalid University Hospital

King Saud University

Riyadh, Saudi Arabia

Haitham M. Al-Salama MD

Director of Research Programmes

Qatar Foundation

Doha, Qatar

Bhupinder Anand MD, PhD

Professor of Medicine

Baylor College of Medicine;

Staff Physician

Michael E. DeBakey VA Medical Center

Houston, TX, USA

Jervoise Andreyev MA, PhD, FRCP

Consultant Gastroenterologist in Pelvic Radiation Disease

The GI Unit

The Royal Marsden NHS Foundation Trust

London, UK

Nadir Arber MD, MSc, MHA

Professor of Medicine and Gastroenterology

Yeichel and Helen Lieber Professor for Cancer Research

Head, Department of Cancer Prevention

The Integrated Cancer Prevention Center

Gastroenterology and Liver Institute

Tel-Aviv Sourasky Medical Center;

Sackler Faculty of Medicine

Tel-Aviv University

Tel-Aviv, Israel

Christian Arnold MD

Department of Gastroenterology

Klinikum Friedrichshafen

Friedrichshafen, Germany

Tarik Asselah MD, PhD

Service d’Hépatologie

Hôpital Beaujon

University of Paris

Clichy, France

John C. Atherton MD

Professor of Gastroenterology and Head of School of Clinical Sciences

Nottingham Digestive Diseases Centre

University of Nottingham and Nottingham University Hospitals

Nottingham, UK

Ashok Attaluri MD

Division of Gastroenterology and Hepatology

Department of Internal Medicine

University of Iowa Carver College of Medicine

Iowa City, IA, USA

Kiran Bambha MD, MSc

Assistant Professor of Medicine

Hepatology and Liver Transplantation

University of Colorado Anschutz Medical Campus

Aurora, CO, USA

Rafael Bañares MD

Professor of Medicine

Hepatology and Liver Unit

Hospital General Universitario Gregorio Marañón

Universidad Complutense

CIBERehd

Madrid, Spain

Matthew R. Banks BSc, PhD, FRCP

Division of Gastroenterology

University College London Hospitals

London, UK

Heike Bantel MD

Department of Gastroenterology, Hepatology and Endocrinology

Hannover Medical School

Hannover, Germany

Alan Barkun MDCM, FRCPC, MSc(Epi)

Division of Gastroenterology

McGill University and the McGill University Health Centre (MUHC)

Montreal, QC, Canada

M. Beaugrand MD

Liver Unit

Hôpital Jean Verdier

Université Paris XIII

Bondy, France

Cristina Bellarosa MD

Centro Studi Fegato

Fondazione Italiana Fegato

University of Trieste

Trieste, Italy

Pascal O. Berberat MD

Department of Surgery

Klinikum rechts der Isar

Technische Universität München

Munich, Germany

Nora V. Bergasa MD

Chief of Medicine

Metropolitan Hospital Center

New York, NY, USA

Annalisa Berzigotti MD, PhD

Hepatic Hemodynamic Laboratory

Liver Unit, Institut de Malalties Digestives i Metaboliques

University of Barcelona, CIBERehd

Barcelona, Spain

Rakesh Bhardwaj MD, FRCS (Gen Surg)

Consultant Colorectal Surgeon

Darent Valley Hospital

Dartford, UK

Adil E. Bharucha MD

Professor of Medicine

Division of Gastroenterology and Hepatology

Clinical Enteric Neuroscience Translational and Epidemiological Research Program

Mayo Clinic

Rochester, MN, USA

Juliane Bingener MD

Associate Professor of Surgery

Division of Gastroenterologic and General Surgery

Mayo Clinic

Rochester, MN, USA

Stephan C. Bischoff MD

Professor of Medicine

Director, Department of Nutritional Medicine and Immunology

University of Hohenheim

Stuttgart, Germany

Ingvar Bjarnason MD, MSc

Professor of Digestive Diseases

Department of Gastroenterology

King’s College Hospital

London, UK

Jaime Bosch MD, PhD

Chair of Medicine

Head, Hepatic Hemodynamic Laboratory, Liver Unit

Hospital Clínic-IDIBAPS, University of Barcelona;

Director, Biomedical Research Centre Network of Hepatic and Digestive Diseases (CIBERehd), National Institute of Health Carlos III

Ministry of Science and Innovation

Barcelona, Spain

Gerd Bouma MD, PhD

Department of Gastroenterology

Vrije Universiteit Medical Center

Amsterdam, The Netherlands

T. E. Bowling MD, FRCP

Consultant in Gastroenterology and Clinical Nutrition

Nottingham University Hospitals

Nottingham, UK

Thomas A. Brown MD

MetroHealth Medical Center;

Division of Gastroenterology and Hepatology

Case Western Reserve University

Cleveland, OH, USA

William R. Brugge MD

Director, Gastrointestinal Endoscopy

Massachusetts General Hospital;

Professor of Medicine

Harvard Medical School

Boston, MA, USA

Miquel Bruguera Cortada MD

Liver Unit, Hospital Clinic, and Department of Medicine

University of Barcelona

Barcelona, Spain

Jordi Bruix MD

Senior Consultant

Professor of Medicine

BCLC Group, Liver Unit

Hospital Clinic

Biomedical Research Centre

Network of Hepatic and Digestive Diseases (CIBERehd)

University of Barcelona

Barcelona, Spain

Markus W. Büchler MD

Professor and Chairman

Department of General Surgery

University of Heidelberg

Heidelberg, Germany

Alan L. Buchman MD, MSPH

Professor of Medicine and Surgery

Division of Gastroenterology

Feinberg School of Medicine

Northwestern University

Chicago, IL, USA

Nicola E. Burch MBChB, MRCP (UK) (Gastro), MSc (Hons)

Consultant Gastroenterologist

University Hospitals Coventry and Warwickshire NHS Trust

Coventry, UK

Christophe Bureau MD

Service d’Hépato-Gastro-Entérologie et INSERM

Université de Toulouse

Toulouse, France

Andrés Cárdenas MD, MMSc

Institut Clinic de Malalties Digestives i Metaboliques

Hospital Clinic

University of Barcelona

Barcelona, Spain

Anna Casburn-Jones MB, MRCP

Consultant Gastroenterologist

St Mary’s Hospital

London, UK

Güralp O. Ceyhan MD

Department of Surgery

Klinikum rechts der Isar

Technische Universität München

Munich, Germany

Francis K.L. Chan MD

Professor of Medicine

Chief of Gastroenterology & Hepatology

Associate Dean (Clinical)

Department of Medicine & Therapeutics

The Chinese University of Hong Kong

Hong Kong SAR, China

Kenneth J. Chang MD

Chief, Division of Gastroenterology

Professor of Clinical Medicine

University of California

Irvine, CA, USA

Daniel Cherqui MD

Professor of Surgery

New York Presbyterian / Weill Cornell Medical College

New York, NY, USA

Runjan Chetty MB BCh, FFPath, FRCPA, FCAP, FRCPath, DPhil (Oxon)

Professor and Director of Translational Pathology and Consultant GI / Pancreatic Pathologist

Department of Cellular Pathology

Nuffield Department of Clinical

Laboratory Sciences and Oxford Biomedical Research Centre

Oxford University Hospitals Trust

University of Oxford

Oxford, UK

Winnie C.W. Chu MBChB, FRCR

Professor

Department of Diagnostic Radiology & Organ Imaging

Chinese University of Hong Kong

Hong Kong SAR, China

Guido Costamagna MD

Director, Gastrointestinal Endoscopy

Catholic University of the Sacred Heart

“A. Gemelli” Hospital

Rome, Italy

John Croese FRACP, MD

Department of Gastroenterology

The Townsville Hospital

Townsville, QLD, Australia

Abraham H. Dachman MD

Department of Radiology

The University of Chicago Medical Center

Chicago, IL, USA

Zilvinas Dambrauskas MD

Department of Surgery

Kaunas University of Medicine Hospital

Kaunas, Lithuania

Gennaro D’Amico MD

Chief of Gastroenterology

Department of Gastroenterology

Ospedale V Cervello

Palermo, Italy

Srinivasan Dasarathy MD

Departments of Gastroenterology, Hepatology and Pathobiology

Cleveland Clinic Lerner College of Medicine

Case Western Reserve University

Cleveland, OH, USA

Mark Davenport ChM FRCS (Eng), FRCS (Paeds)

Professor of Paediatric Surgery

Department of Paediatric Surgery

King’s College Hospital

London, UK

Andrea De Gottardi MD, PhD

Visiting Hepatologist

Hepatic Hemodynamic Laboratory, Liver Unit

Hospital Clinic

Barcelona, Spain

Amar R. Deshpande MD

Assistant Professor of Medicine

Department of Medicine, Division of Gastroenterology

University of Miami Miller School of Medicine

Miami, FL, USA

Jean-Charles Deybach MD, PhD

Professor of Medicine

Head of Department of Biochemistry and Molecular Genetics

Centre Français des Porhpyries

Hôpital Louis Mourier

Colombes, France

Daniel Dhumeaux MD

Henri Mondor Hospital

Créteil, France

Elizabeth Drewe MD

Department Clinical Immunology and Allergy

Nottingham University Hospitals

Nottingham, UK

Franz Ludwig Dumoulin MD

Head of Department of Medicine

Gemeinschaftskrankenhaus Bonn;

Associate Professor of Medicine

University of Bonn

Bonn, Germany

Andrew W. DuPont MD, MSPH

The University of Texas Health Science Center at Houston

Houston, TX, USA

Herbert L. DuPont MD

Director, Center for Infectious Diseases

Professor of Epidemiology

The University of Texas-Houston School of Public Health;

Chief, Internal Medicine Service

St. Luke’s Episcopal Hospital;

Vice Chairman, Department of Medicine

Baylor College of Medicine

Houston, TX, USA

Luca Fabris MD, PhD

Assistant Professor of Gastroenterology

Department of Surgical, Oncological and Gastroenterological Sciences

University of Padua, Padua, Italy;

Liver Center and Section of Digestive Diseases

Yale University

New Haven, CT, USA

Michael B. Fallon MD

Division Director and Professor of Medicine

Division of Gastroenterology, Hepatology and Nutrition

The University of Texas Health Science Center at Houston

Houston, TX, USA

Dai-ming Fan MD, PhD

Xijing Hospital of Digestive Diseases

State Key Laboratory of Cancer Biology

Fourth Military Medical University

Xi’an, China

Patrizia Farci MD

Chief, Hepatic Pathogenesis Section

Laboratory of Infectious Diseases

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Bethesda, MD, USA

Michael J.G. Farthing MD, FRCP

Vice Chancellor and Professor of Medicine

University of Sussex

Brighton, UK

Ronnie Fass MD

Professor of Medicine

University of Arizona College of Medicine;

Chief of Gastroenterology

Head, Neuroenteric Clinical Research Group

Southern Arizona VA Health Care System

Tucson, AZ, USA

Peter Ferenci MD

Professor of Medicine

Department of Internal Medicine

Gastroenterology and Hepatology

Medical University of Vienna

Vienna, Austria

Katrin Feuser PhD

Department of Nutritional Medicine

University of Hohenheim

Stuttgart, Germany

Martin H. Floch MD, MACG, AGAF, FACP

Clinical Professor of Medicine

Yale University School of Medicine

New Haven, CT, USA

Evan L. Fogel MD

Professor of Clinical Medicine

Division of Gastroenterology / Hepatology

Indiana University Health

Indianapolis, IN, USA

Alexander C. Ford MBChB, MD

Department of Academic Medicine

St. James’s University Hospital

Leeds, UK

Alejandro Forner MD

Clinical Research Associate

BCLC Group, Liver Unit

ICMDM, Hospital Clinic

Biomedical Research Centre Network of Hepatic and Digestive Diseases (CIBERehd)

University of Barcelona

Barcelona, Spain

Xavier Forns MD, PhD

Consultant in Liver Diseases

Hospital Clinic, CIBERehd, IDIBAPS

Barcelona, Spain

Paul J. Fortun BM, MRCP, FRACP

Consultant Gastroenterologist

Department of Gastroenterology

Royal Cornwall Hospitals NHS Trust

Truro, UK

Bruce M. Fox MBBS, MRCP, FRCR, PGCE

Consultant GI Radiologist

Honorary University Fellow

Derriford Hospital

Plymouth, UK

Juan Miguel Abdo Francis MD

Division of Medicine

Hospital General de México

Mexico City, Mexico

Helmut Friess MD

Professor and Chairman

Department of Surgery

Klinikum rechts der Isar

Technische Universität München

Munich, Germany

James Frith MB ChB MRCP, PhD

Academic Clinical Lecturer

UK NIHR Biomedical Research Centre in Ageing

Institute for Ageing and Health

Newcastle University

Newcastle upon Tyne, UK

Juan Carlos García-Pagán MD

Senior Consultant in Hepatology

Hepatic Hemodynamic Laboratory

Liver Unit, Hospital Clínic, CIBERehd

Barcelona, Spain

Guadalupe Garcia-Tsao MD

Professor of Medicine

Section of Digestive Diseases

Yale University, School of Medicine

New Haven;

Veterans Affairs Connecticut Healthcare System

West Haven, CT, USA

Robert H. Geelkerken MD PhD

Consultant Vascular Surgeon

Department of Vascular Surgery

Medisch Spectrum Twente

Enschede, The Netherlands

Robert M. Genta MD

Chief for Academic Affairs

Caris Diagnostics / Miraca;

Clinical Professor of Pathology and Medicine (Gastroenterology)

University of Texas Southwestern Medical Center

Irving, TX, USA

Paula Ghaneh MBChB, MD, FRCS

Reader in Surgery

Department of Molecular and Clinical Cancer Medicine

Institute of Translational Medicine

University of Liverpool

Liverpool, UK

Kevin A. Ghassemi MD

Division of Digestive Diseases

David Geffen School of Medicine at UCLA

Los Angeles, CA, USA

Alexander Gimson FRCP

Clinical Director, Division of Medicine

Consultant Physician and Hepatologist

Liver Transplantation Unit

Cambridge University Hospitals NHS Foundation Trust

Cambridge, UK

Pere Ginès MD

Chairman, Liver Unit

Professor of Medicine

Hospital Clinic

University of Barcelona

Barcelona, Spain

Ajay Goel PhD

Director, Epigenetics and Cancer Prevention

Baylor Research Institute and Charles A Sammons Cancer Center

Baylor University Medical Center

Dallas, TX, USA

Martin Goetz MD, PhD

Internist, Gastroenterologe

I. Medizinische Klinik und Poliklinik

Universitätsmedizin Mainz

Mainz, Germany

Tamas A. Gonda MD

Assistant Professor of Medicine

Division of Digestive and Liver Diseases

Columbia University Medical Center

New York, NY, USA

Gregory J. Gores MD

Reuben R. Eisenberg Professor of Medicine

Chair, Division of Gastroenterology and Hepatology

Center for Basic Research in Digestive Diseases

Mayo Clinic

Rochester, MN, USA

Penny A. Gowland PhD

Sir Peter Mansfield Magnetic Resonance Centre

School of Physics and Astronomy

University of Nottingham

Nottingham, UK

Andrea Grin MD, FRCPC

Resident in Pathology

Department of Laboratory Medicine and Pathobiology

University of Toronto

Toronto, ON, Canada

Roberto J. Groszmann MD

Department of Internal Medicine

Digestive Diseases Section

Yale University School of Medicine

New Haven, CT, USA

Madhusudan Grover MBBS

Mayo Clinic

Rochester, MN, USA

Sushovan Guha MD, PhD

Assistant Professor

Department of Gastroenterology, Hepatology, and Nutrition

The University of Texas MD Anderson Cancer Center

Houston, TX, USA

Neil Gupta MD, MPH

Fellow

Division of Gastroenterology / Hepatology

University of Kansas Medical Center

Kansas City Veterans Administration

Kansas City, MO, USA

Aliya G. Hasan MD

Assistant Professor of Medicine

Division of Gastroenterology and Hepatology

University of Colorado Denver

Aurora, CO, USA

C. J. Hawkey FMedSci

Professor of Gastroenterology

Nottingham Digestive Diseases Centre

University of Nottingham and Nottingham University Hospitals

Nottingham, UK

Philip N. Hawkins PhD, FRCP

National Amyloidosis Centre

Centre for Amyloidosis and Acute Phase Proteins

Division of Medicine

University College London Medical School

London, UK

J. Eileen Hay MB, ChB

Professor of Medicine

Consultant in Gastroenterology and Hepatology

Mayo Clinic

Rochester, MN, USA

J. Michael Henderson MD

Chief Quality Officer and Staff Surgeon

Cleveland Clinic

Cleveland, OH, USA

Karin Herrmann MD

Associate Professor of Radiology

Institute of Clinical Radiology

Ludwig-Maximilians-University of Munich

Munich, Germany

Tiberiu Hershcovici MD

Research Fellow

Neuroenteric Clinical Research Group

Southern Arizona VA Health Care System

Tucson, AZ, USA

Frank Hoentjen MD, PhD

Assistant Professor in Medicine

Department of Gastroenterology

Radboud University Medical Center

Nijmegen, The Netherlands

Joyce Wai Yi Hui MBChB, FRCR

Department of Diagnostic Radiology and Organ Imaging

Prince of Wales Hospital

The Chinese University of Hong Kong

Shatin, Hong Kong SAR, China

David J. Humes BSc MBBS MRCS PhD

NIHR Lecturer in Surgery

Nottingham Digestive Diseases Centre

Nottingham University Hospitals

Nottingham, UK

Haruhiro Inoue MD

Professor

Faculty of Medicine

Showa University;

Showa University International Training Center for Endoscopy (SUITE)

Digestive Disease Center

Showa University Northern Yokohama Hospital

Yokohama, Japan

Christian S. Jackson MD

Chief, Section of Gastroenterology

Loma Linda VA Healthcare System;

Assistant Professor

Loma Linda University Medical Center

Loma Linda, CA, USA

Simon A. Jackson MBBS, FRCS, FRCR

Consultant GI Radiologist

Imaging Directorate

Derriford Hospital

Plymouth, UK

Janusz A. Jankowski MD, PhD, FRCP, FACG

Consultant Gastroenterologist

Digestive Diseases Centre UHL Trust

Leicester;

James Black Senior Fellow and Professor

University of Oxford

Oxford;

Fellow and Professor

Cancer Research UK and Queen Mary, University of London

London, UK

Dennis M. Jensen MD

CURE / Digestive Disease Research Center

David Geffen School of Medicine at UCLA

Los Angeles, CA, USA

Robert T. Jensen MD

Chief, Cell Biology Section

Digestive Diseases Branch

National Institute of Diabetes and Kidney Diseases

National Institutes of Health

Bethesda, MD, USA

Michael D. Johnson MD

Hepato-Pancreato-Biliary and Transplant Surgery

Cleveland Clinic

Cleveland, OH, USA

Rome Jutabha MD

Director, UCLA Center for Small Bowel Diseases

Division of Digestive Diseases

David Geffen School of Medicine at UCLA

Los Angeles, CA, USA

Peter J. Kahrilas MD

Gilbert H. Marquardt Professor of Medicine

Department of Medicine

Division of Gastroenterology

Feinberg School of Medicine

Northwestern University

Chicago, IL, USA

Anthony N. Kalloo MD

The Moses and Helen Golden Paulson Professor of Gastroenterology

The Johns Hopkins University School of Medicine;

Chief, Division of Gastroenterology and Hepatology

Johns Hopkins Hospital

Baltimore, MD, USA

Patrick S. Kamath MD

Professor of Medicine

Consultant and Vice Chair (Education)

Division of Gastroenterology and Hepatology

Mayo Clinic

Rochester, MN, USA

Philip O. Katz MD

Clinical Professor of Medicine

Jefferson Medical College

Thomas Jefferson University;

Chairman, Division of Gastroenterology

Albert Einstein Medical Center

Philadelphia, PA, USA

Ciarán P. Kelly MD

Professor of Medicine

Harvard Medical School;

Director of the Celiac Center

Beth Israel Deaconess Medical Center

Boston, MA, USA

David J. Kerr CBE, MA, MD, DSc, FRCP(Glas,Lon & Edin), FRCGP(Hon), FMedSci

Professor of Cancer Medicine

Nuffield Department of Clinical and Laboratory Sciences

University of Oxford

Oxford, UK;

Adjunct Professor of Medicine

Professor of Cancer Therapeutics

Weill-Cornell College of Medicine

New York, NY, USA

David Kershenobich MD, PhD

Department of Experimental Medicine

Faculty of Medicine, UNAM

Hospital General de México

Mexico City, Mexico

Arjun Khosla MD

University Hospitals Case Medical Center

Cleveland, OH, USA

Ralf Kiesslich MD, PhD

Head of Endoscopy Department

I. Medizinische Klinik und Poliklinik

Universitätsmedizin Mainz

Mainz, Germany

Kazufumi Kimura MD, PhD

Research Fellow

Microbiology and Immunology

School of Biomedical, Biomolecular and Chemical Sciences

University of Western Australia

Perth, WA, Australia

Michael S. Kipper MD

Clinical Professor of Radiology

University of California at San Diego

San Diego, CA, USA

Rajan Kochar MD, MPH

Assistant Professor of Medicine

Division of Gastroenterology, Hepatology and Nutrition

The University of Texas Health Science Center at Houston

Houston, TX, USA

Jeroen J. Kolkman MD

Consultant Gastroenterologist

Medisch Spectrum Twente

Enschede, The Netherlands

Ayman Koteish MD

Assistant Professor of Medicine

Division of Gastroenterology

The Johns Hopkins University School of Medicine

Baltimore, MD, USA

Thomas O.G. Kovacs MD

Professor of Medicine

CURE / Digestive Disease Research Center

David Geffen School of Medicine at UCLA

Los Angeles, CA, USA

Benjamin Krevsky MD, MPH

Professor of Medicine

Temple University School of Medicine

Philadelphia, PA, USA

Olivier Lada PhD

Service d’Hépatologie

Hôpital Beaujon

University of Paris

Clichy, France

Maria Eliana Lai MD

Professor of Medicine

Department of Medical Sciences

University of Cagliari

Policlinico Universitario

Monserrato, Cagliari, Italy

Richard H. Lash MD

Chief Medical Officer

Caris Diagnostics / Miraca;

Clinical Associate Professor

University of Texas Southwestern Medical Center

Irving, TX, USA

James Y.W. Lau FRCS (Edin)

Department of Surgery

Chinese University of Hong Kong

Hong Kong SAR, China

Konstantinos N. Lazaridis MD

Division of Gastroenterology and Hepatology

Center for Basic Research in Digestive Diseases

Mayo Clinic

Rochester, MN, USA

Philippe Lefere MD

Department of Radiology

Stedelijk Ziekenhuis

Roeselare, Belgium

Daniel A. Leffler MD

Assistant Professor of Medicine

Division of Gastroenterology and Hepatology;

Director of Clinical Research at the Celiac Center

Beth Israel Deaconess Medical Center

Harvard Medical School

Boston, MA, USA

Keith Leiper MD (deceased)

Consultant Gastroenterologist

Department of Gastroenterology

Royal Liverpool University Hospital

Liverpool, UK

Vivian Y.F. Leung PDDR, PhD

Senior Radiographer

Department of Diagnostic Radiology & Organ Imaging

Chinese University of Hong Kong

Hong Kong SAR, China

Joel S. Levine MD

Professor of Medicine

Division of Gastroenterology and Hepatology

University of Colorado Denver

Aurora, CO, USA

Blair S. Lewis MD, PC

Clinical Professor of Medicine

Mount Sinai School of Medicine

New York, NY, USA

Charles J. Lightdale MD

Professor of Clinical Medicine

Division of Digestive and Liver Diseases

Columbia University Medical Center

New York, NY, USA

Keith D. Lindor MD

Executive Vice Provost Health Solutions

Arizona State University

Tempe, AZ, USA

Dileep N. Lobo MS, DM, FRCS, FACS

Professor of Gastrointestinal Surgery

Division of Gastrointestinal Surgery

Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit

Nottingham University Hospitals

Nottingham, UK

Alain Luciani MD, PhD

Henri Mondor Hospital

Créteil, France

Michael R. Lucey MD

Professor of Medicine

Chief, Section of Gastroenterology and Hepatology

University of Wisconsin School of Medicine and Public Health

Madison, WI, USA

Ryan D. Madanick MD

Assistant Professor of Medicine

Department of Medicine, Division of Gastroenterology and Hepatology

University of North Carolina School of Medicine

Chapel Hill, NC, USA

Yashwant R. Mahida MD

Professor of Medicine

Institute of Infection, Immunity and Inflammation

Nottingham University Hospitals

Nottingham, UK

Erica Makin MSc, FRCS(Paeds)

Specialist Registrar

King’s College Hospital

London, UK

Giuseppe Malizia MD

Consultant in Gastroenterology

Department of Gastroenterology

Ospedale V Cervello

Palermo, Italy

Jayan Mannath MD, MRCP

Research Fellow

Nottingham Digestive Diseases Centre and Biomedical Research Unit

University of Nottingham and Nottingham University Hospitals

Nottingham, UK

Michael P. Manns MD

Professor and Chairman

Department of Gastroenterology, Hepatology and Endocrinology

Hannover Medical School

Hannover, Germany

Magnus J. Mansard MS

Senior Registrar

Department of Surgical Gastroenterology

Asian Institute of Gastroenterology

Hyderabad, India

Patrick Marcellin MD, PhD

Service d’Hépatologie

Hôpital Beaujon

University of Paris

Clichy, France

Luca Marciani PhD

Lecturer in GI MRI

Nottingham Digestive Diseases Centre and NIHR Biomedical Research Unit

School of Clinical Sciences

University of Nottingham and Nottingham University Hospitals

Nottingham, UK

Michele Marchese MD

Gastrointestinal Endoscopy Unit

Catholic University of the Sacred Heart

“A. Gemelli” Hospital

Rome, Italy

Barry J. Marshall MD, FRACP

Clinical Professor

Microbiology and Immunology

School of Biomedical, Biomolecular and Chemical Sciences

University of Western Australia

Perth, WA, Australia

Cindy Matsen MD

Resident, General Surgery

University of Utah

Salt Lake City, UT, USA

Catherine McCrann MD

Gastroenterology Fellow

Yale University

New Haven, CT, USA

Arthur J. McCullough MD

Professor of Medicine

Cleveland Clinic Lerner College of Medicine

Case Western Reserve University

Digestive Diseases Institute

Cleveland, OH, USA

George B. McDonald MD

Professor of Medicine

University of Washington;

Gastroenterology / Hepatology Section

Fred Hutchinson Cancer Research Center

Seattle, WA, USA

Dermot McGovern MD, PhD

Cedars-Sinai IBD Center

Los Angeles, CA, USA

Donald P. McManus BSc(Hons), PhD, DSc

National Health and Medical Research Council of Australia Senior Principal Research Fellow

Professor and Laboratory Head

Queensland Institute of Medical Research

Brisbane, QLD, Australia

A. Merrie MBChB, PhD, FRACS

Consultant Surgeon

Discipline of Oncology

Faculty of Medical and Health Sciences

University of Auckland

Auckland, New Zealand

Rachel S. Midgley MD, BSc(Hons) MB ChB(Hons) FRCP, PhD

Consultant Medical Oncologist and DH / HEFCE Clinical Senior Lecturer

Department of Oncology

University of Oxford

Oxford, UK

Giorgina Mieli-Vergani MD, PhD

Alex Mowat Professor of Paediatric Hepatology

Department of Child Health and Institute of Liver Studies

King’s College Hospital

London, UK

Hitomi Minami MD

Faculty of Medicine, Showa University

Showa University

Showa University International Training Center for Endoscopy (SUITE)

Digestive Disease Center

Showa University Northern Yokohama Hospital

Yokohama, Japan

Paul Moayyedi BSc, MB ChB, PhD, MPH, FRCP (London), FRCPC, FACG, AGAF

Director, Division of Gastroenterology

Department of Medicine

Health Sciences Centre

McMaster University

Hamilton, ON, Canada

Dana C. Moffatt MD

Division of Gastroenterology / Hepatology

Indiana University Health

Indianapolis, IN, USA

Tanya M. Monaghan BSc (Hons), BSc (Hons), BM, MRCP

Specialist Registrar in Gastroenterology

Institute of Infection, Immunity and Inflammation

Nottingham University Hospitals

Nottingham, UK

Andrew R. Moore MBChB, MRCP

Specialist Registrar in Gastroenterology

Royal Liverpool University Hospital

Clinical Research Fellow

Institute of Translational Medicine

University of Liverpool

Liverpool, UK

Rosa Miquel Morera MD

Pathology Department

Hospital Clinic and University of Barcelona

Barcelona, Spain

Koenraad J. Mortele MD

Department of Radiology

Beth Israel Deaconess Medical Center

Harvard Medical School

Boston, MA, USA

N. Mortensen MD, FRCS

Professor of Surgery

Nuffield Department of Surgery

University of Oxford

Oxford, UK

Menachem Moshkowitz MD

The Integrated Cancer Prevention Center

Gastroenterology and Liver Institute

Tel-Aviv Medical Center;

Sackler Faculty of Medicine

Tel-Aviv University

Tel-Aviv, Israel

Rami Moucari MD, PhD

Service d’Hépatologie

Hôpital Beaujon

University of Paris

Clichy, France

Chris Mulder MD, PhD

Department of Gastroenterology

Vrije Universiteit Medical Center

Amsterdam, The Netherlands

Kevin D. Mullen MD

MetroHealth Medical Center;

Division of Gastroenterology and Hepatology

Case Western Reserve University

Cleveland, OH, USA

Ulf Müller-Ladner MD

Chair, Department for Internal Medicine and Rheumatology

Justus-Liebig University Giessen;

Department for Rheumatology and Clinical Immunology

Kerckhoff Clinic

Bad Nauheim, Germany

Simon Murch PhD, FRCP, FRCPCH

Professor of Paediatrics and Child Health

Division of Metabolic and Vascular Health

Warwick Medical School

The University of Warwick

Coventry, UK

V. Raman Muthusamy MD

Director, Gastroenterology Fellowship Program, Health Sciences Associate

Clinical Professor of Medicine

H.H. Chao Comprehensive Digestive Disease Center

Division of Gastroenterology

Department of Medicine

University of California

Irvine, CA, USA

John P. Neoptolemos FMedSci

The Owen and Ellen Evans Chair of Surgery

Director Liverpool Cancer Research UK Centre

Department of Molecular and Clinical Cancer Medicine

Institute of Translational Medicine

University of Liverpool

Liverpool, UK

Leigh Neumayer MD

Professor of Surgery

University of Utah

Salt Lake City, UT, USA

Julia L. Newton MBBS, FRCP, PhD

Professor of Ageing – Medicine

UK NIHR Biomedical Research Centre in Ageing

Institute for Ageing and Health

Newcastle University

Newcastle upon Tyne, UK

Timothy T. Nostrant MD

Professor

Department of Internal Medicine

University of Michigan Health Center

Ann Arbor, MI, USA

Kjell Öberg MD, PhD

Professor of Endocrine Oncology

Department of Medical Sciences

Endocrine Oncology

Uppsala University Hospital

Uppsala, Sweden

Sebastian Obrzut MD

Assistant Professor of Radiology

University of California at San Diego

San Diego, CA, USA

John G. O’Grady MD, FRCPI

Consultant Hepatologist

Institute of Liver Studies

King’s College School of Medicine

London, UK

Philippe Otal MD

Service de Radiologie

Université de Toulouse

Toulouse, France

Bergein F. Overholt MD

Center of Excellence for Treatment of Barrett’s Esophagus

Thomson Cancer Survival Center

Knoxville, TN, USA

Masoud Panjehpour PhD

Center of Excellence for Treatment of Barrett’s Esophagus

Thomson Cancer Survival Center

Knoxville, TN, USA

Georgios Papachristou MD

Division of Gastroenterology, Hepatology and Nutrition

Departments of Medicine

University of Pittsburgh

Pittsburgh, PA, USA

Michael C. Parker BSc, MS, FRCS, FRCS (Ed)

Fawkham Manor Hospital

Fawkham, UK

Henry P. Parkman MD

Professor of Medicine

Director, GI Motility Laboratory;

Gastroenterology Section

Department of Medicine

Temple University School of Medicine

Philadelphia, PA, USA

Stephen P. Pereira BSc, PhD, FRCP, FRCPE

Reader in Hepatology and Gastroenterology

University College London Hospitals

London, UK

David H. Perlmutter MD

Vira I. Heinz Professor and Chair

Department of Pediatrics

Professor of Cell Biology and Physiology

University of Pittsburgh School of Medicine;

Physician-in-Chief and Scientific Director

Children’s Hospital of Pittsburgh of UPMC

Pittsburgh, PA, USA

Lucio Petruzziello MD

Gastrointestinal Endoscopy Unit

Catholic University of the Sacred Heart

“A. Gemelli” Hospital

Rome, Italy

Patrick R. Pfau MD

Associate Professor of Medicine

Chief of Clinical Gastroenterology

Section of Gastroenterology and Hepatology

University of Wisconsin School of Medicine and Public Health

Madison, WI, USA

Antonello Pietrangelo MD, PhD

Professor of Medicine

Head, Division of Internal Medicine

and “Mario Coppo” Liver Research Center

University Hospital of Modena

Modena, Italy

Jeffrey L. Ponsky MD

Chairman, Department of Surgery

University Hospitals of Cleveland

Cleveland, OH, USA

Todd A. Ponsky MD

Associate Professor

Division of Pediatric Surgery

Rainbow Babies & Children’s Hospital

University Hospitals Case Medical Center

Cleveland, OH, USA

John J. Poterucha MD

Professor of Medicine

Division of Gastroenterology and Hepatology

Mayo Clinic

Rochester, MN, USA

Benjamin K. Poulose MD, MPH

Assistant Professor

Department of Surgery

Vanderbilt University Medical Center

Nashville, TN, USA

Raoul Poupon MD

Université Pierre et Marie Curie

AP-Hôpitaux de Paris

Service d’Hepatologie

Hôpital Saint-Antoine

Paris, France

Hervé Puy MD, PhD

Professor of Medicine

Centre Français des Porhpyries

Hôpital Louis Mourier

Colombes, France

Rodrigo M. Quera MD

Gastroenterologist

Clinica Las Condes

Santiago, Chile

Eamonn M. M. Quigley MD, FRCP, FACP, FACG, FRCPI

Professor of Medicine and Human Physiology

Alimentary Pharmabiotic Centre

University College Cork

Cork, Ireland

Krish Ragunath MD, DNB, MPhil, FRCP

Associate Professor and Reader in GI Endoscopy

Nottingham Digestive Diseases Centre and Biomedical Research Unit

University of Nottingham and Nottingham University Hospitals

Nottingham, UK

G. V. Rao MS, MAMS

Director and Chief of Gastrointestinal and Minimally Invasive Surgery

Department of Surgical Gastroenterology

Asian Institute of Gastroenterology

Hyderabad, India

Satish S. C. Rao MD, FRCP (Lon), PhD

Professor of Medicine

Chief, Gastroenterology / Hepatology

Director, Digestive Health Center

Medical College of Georgia

Georgia Health Sciences University

Augusta, GA;

President

American Neurogastroenterology & Motility Society / FBG

Belleville, MI, USA