Table of Contents
Cover
Related Titles
Title Page
Copyright
Dedication
List of Contributors
Foreword 1
Foreword 2
Preface
Chapter 1: Computational Studies of Heteroatom-Assisted C−H Activation at Ru, Rh, Ir, and Pd as a Basis for Heterocycle Synthesis and Derivatization
1.1 Introduction
1.2 Palladium
1.3 Ruthenium, Rhodium, and Iridium
1.4 Conclusions
Acknowledgments
References
Chapter 2: Pd-Catalyzed Synthesis of Nitrogen-Containing Heterocycles
2.1 Introduction
2.2 General Consideration on Palladium Chemistry
2.3 Heterocycle Synthesis via C(sp
3
)−H Activation
2.4 Heterocycles via C(sp
2
)−H Activation
2.5 Conclusions
References
Chapter 3: Pd-Catalyzed Synthesis of Oxygen-Containing Heterocycles
3.1 Introduction
3.2 Palladium-Catalyzed C−H Activation/C−C Formation to Construct Oxacycles
3.3 Palladium-Catalyzed C−H Activation/C−O Formation to Construct Oxacycles
3.4 Conclusions
References
Chapter 4: Pd-Catalyzed Synthesis of Other Heteroatom-Containing Heterocycles
4.1 Introduction
4.2 Sulfur-Containing Heterocycles
4.3 Phosphorus-Containing Heterocycles
4.4 Silicon-Containing Heterocycles
4.5 Summary and Conclusions
References
Chapter 5: Rh-Catalyzed Synthesis of Nitrogen-Containing Heterocycles
5.1 Introduction
5.2 Synthesis of Five-Membered Nitrogen Heterocycles
5.3 Synthesis of Six-Membered Nitrogen Heterocycles
5.4 Synthesis of Quaternary Ammonium Salts
5.5 Synthesis of Seven-Membered Nitrogen Heterocycles
5.6 Summary and Conclusions
References
Chapter 6: Rh-Catalyzed Synthesis of Oxygen-Containing Heterocycles
6.1 Introduction
6.2 Synthesis of Five-Membered Oxygen-Containing Heterocycles
6.3 Synthesis of Six-Membered Oxygen-Containing Heterocycles
6.4 Synthesis of Seven-, Eight-, and Nine-Membered Oxygen-Containing Heterocycles
6.5 Summary and Conclusions
References
Chapter 7: Ruthenium-Catalyzed Synthesis of Heterocycles via C−H Bond Activation
7.1 Introduction
7.2 Ruthenium-Catalyzed Heterocycle Synthesis via Intramolecular C−C Bond Formation Based on C−H Bond Activation
7.3 Ruthenium-Catalyzed Heterocycle Synthesis via Intramolecular C−N Bond Formation Based on C−H Bond Activation
7.4 Ruthenium-Catalyzed Heterocycle Synthesis via Intermolecular C−C/C−O Bond Formation Based on C−H Bond Activation
7.5 Ruthenium-Catalyzed Heterocycle Synthesis via Intermolecular C−C/C−N Bond Formation Based on C−H Bond Activation
7.6 Summary and Conclusions
References
Chapter 8: Cu-Catalyzed Heterocycle Synthesis
8.1 Introduction
8.2 Four-Membered-Ring Formation
8.3 Five-Membered-Ring Formation
8.4 Six-Membered-Ring Formation
8.5 Summary
References
Chapter 9: Fe- and Ag-Catalyzed Synthesis of Heterocycles
9.1 Introduction
9.2 Iron-Catalyzed Synthesis of Heterocycles
9.3 Silver-Catalyzed Synthesis of Heterocycles
9.4 Conclusion and Outlook
References
Chapter 10: Heterocycles Synthesis via Co-Catalyzed C−H Bond Functionalization
10.1 Introduction
10.2 Heterocycle Synthesis via Low-Valent Cobalt-Catalyzed C−H Activation
10.3 Heterocycle Synthesis via High-Valent Cobalt-Catalyzed C−H Activation
10.4 Heterocycle Synthesis via C−H Functionalization under Co(II)-Based Metalloradical Catalysis
10.5 Summary and Conclusions
References
Chapter 11: Ir-Catalyzed Heterocycles Synthesis
11.1 Introduction
11.2 Ir-Catalyzed Heterocyclization by
ortho
-Aryl C−H Activation
11.3 Ir-Catalyzed Heterocyclization by Benzylic C−H Activation
11.4 Ir-Catalyzed Heterocyclization by sp
3
C−H Activation
11.5 Heterocyclization by Ir Catalyst as Lewis Acid
11.6 Ir-Catalyzed Heterocyclization by C−H Bond Activation through Transfer Hydrogenation
11.7 Miscellaneous Reactions
11.8 Summary and Conclusions
References
Chapter 12: Au- and Pt-Catalyzed C−H Activation/Functionalizations for the Synthesis of Heterocycles
12.1 Introduction
12.2 Synthesis of
O
-Heterocycles
12.3 Synthesis of
N
-Heterocycles
12.4 Synthesis of
S
-Heterocycles
12.5 Synthesis of
O
-Heterocycles and
N
-Heterocycles
12.6 Synthesis of Fused Polycyclic Polyheterocycles
12.7 Conclusions
References
Chapter 13: Heterocycle Synthesis Based on Visible-Light-Induced Photocatalytic C−H Functionalization
13.1 Introduction
13.2
de novo
Synthesis of Heterocycles
13.3 Direct C−H Functionalization of Heteroarenes
13.4 Summary and Outlook
References
Chapter 14: Heterogeneous C−H Activation for the Heterocycle Synthesis
14.1 Introduction
14.2 Heterogeneous Pd-Catalyzed Heterocycle Synthesis via C−H Activation
14.3 Heterogeneous Photocatalysis for the Heterocycle Synthesis via C−H Activation
14.4 Summary
References
Chapter 15: Transition Metal-Catalyzed Carbonylative Synthesis of Heterocycles via C−H Activation
15.1 Introduction
15.2 Cobalt-Catalyzed Heterocyclic Synthesis via Carbonylative C−H Activation
15.3 Rhodium-Catalyzed Heterocyclic Synthesis via Carbonylative C−H Activation
15.4 Ruthenium-Catalyzed Heterocyclic Synthesis via Carbonylative C−H Activation
15.5 Palladium-Catalyzed Heterocyclic Synthesis via Carbonylative C−H Activation
15.6 Summary and Outlook
References
Chapter 16: Synthesis of Natural Products and Pharmaceuticals via Catalytic C−H Functionalization
16.1 Introduction
16.2 Natural Products Containing Heteroaromatics
16.3 Summary
References
Index
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Guide
Cover
Table of Contents
Foreword 1
Preface
Begin Reading