Details

<p>Foreword vii</p> <p>List of Contributors ix</p> <p>Series Preface xi</p> <p>About the Companion Website xiii</p> <p>1 Neuroanatomy of Feeding Pathways 1<br /> <i>Brian J. Oldfield, Paul N. Mirabella, and Aneta Stefanidis</i></p> <p>2 Afferent Endocrine Control of Eating 24<br /> <i>Wolfgang Langhans and Jens Juul Holst</i></p> <p>3 Ontogeny of Neuroendocrine Feeding Circuits 55<br /> <i>Sophie Croizier and Sebastien G. Bouret</i></p> <p>4 Hypothalamic Peptides and Meal Patterns 76<br /> <i>Yada Treesukosol and Timothy H. Moran</i></p> <p>5 Food Hedonics: Insight from Animal Models 90<br /> <i>Karolina P. Skibicka and Scott E. Kanoski</i></p> <p>6 Functional and Anatomical Dissection of Feeding Circuits 112<br /> <i>Deniz Atasoy and Scott M. Sternson</i></p> <p>7 Exploring Appetite and Hypothalamic Circuitry through Manipulating Gene Expression 134<br /> <i>Tara Jois and Mark W. Sleeman</i></p> <p>8 Electrophysiology of the Appetite‐Regulating Circuits of the Hypothalamus 151<br /> <i>Nancy Sabatier, John Menzies, and Gareth Leng</i></p> <p>9 Functional Neuroimaging of Appetite and Gut–Brain Interactions 174<br /> <i>Paul A.M. Smeets and Hubert Preissl</i></p> <p>10 Appetite Disorders: From Binge Eating to Anorexia Nervosa 201<br /> <i>Mathieu Méquinion, Susanne la Fleur, and Odile Viltart</i></p> <p>11 Future Prospects of the Management of Appetite Disorders Bariatric Surgery 224<br /> <i>Carel le Roux and Karl Neff</i></p> <p>12 Discovery of New Drugs for Weight Loss and Prevention of Weight Regain 247<br /> <i>Anders Lehmann, Udo Bauer, Stephan Hjorth, Rudolph L. Leibel and Michael Rosenbaum</i></p> <p>Index 000</p>

<p><b>Professor Suzanne L Dickson</b>, The Sahlgrenska Academy of the University of Gothenberg, Sweden</p> <p><b>Professor Julian G. Mercer</b>, Rowett Institute of Nutrition and Health, University of Aberdeen, UK</p>

<p>The regulation of appetite - the desire to eat food - in response to hunger, is fundamental to survival. Multiple feedback systems signal the need to consume food, and elicit the behaviours that result in the ingestion of foods of appropriate energy and macronutrient content. The efficiency of these systems is not only key to survival and reproduction, but also underlies clinical issues such as obesity and clinical inappetance, at opposite ends of the spectrum of malnutrition. Consequently, the neuroendocrine pathways in the brain that relate to metabolic need, food choice and desirability, and the feedback that these systems receive from the gastrointestinal tract and food processing are of importance in a wide range of related research areas in the biosciences.</p> <p><i>Neuroendocrinology of Appetite</i> provides researchers and students with a state-of-the-art account of this key interface between physiology and behaviour - the brain areas, pathways and signalling molecules, and the gut signals and processes that are involved in metabolic and hedonic drives to eat. Chapters cover contemporary research tools and approaches, including translational pre-clinical models, the activity of the human brain, and the future of surgical and pharmacological therapies for obesity and eating disorders.</p> <p>This is the fifth volume in the Masterclass in Neuroendocrinology Series, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.</p> <p>Series Editors: John A. Russell, University of Edinburgh, UK<br />and William E. Armstrong, The University of Tennessee, USA</p>

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