Details

Marine Microbiology


Marine Microbiology

Bioactive Compounds and Biotechnological Applications
1. Aufl.

von: Se-Kwon Kim

185,00 €

Verlag: Wiley-VCH
Format: PDF
Veröffentl.: 05.06.2013
ISBN/EAN: 9783527665280
Sprache: englisch
Anzahl Seiten: 580

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Beschreibungen

Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues. Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.
PREFACE INTRODUCTION TO MARINE ACTINOBACTERIA Introduction Actinobacteria Origin and Distribution of Marine Actinobacteria Isolation and Identification of Marine Actinobacteria Indigenous Marine Actinobacteria Role of Actinobacteria in the Marine Environment Importance of Marine Actinobacteria Symbioses Bioinformatics Conclusions TREASURE HUNTING FOR USEFUL MICROORGANISMS IN THE MARINE ENVIRONMENT Introduction Microorganisms Living in the Marine Environment Microorganisms Living in Deep Sea Water STRATEGY OF MARINE VIRUSES IN GLOBAL ECOSYSTEM Introduction Reproductive Strategies of Viruses Abundance of Marine Viruses Viral Activities in Ecosystems Recent Advancement of Viruses versus Diseases The Effect of Ocean Acidification on Marine Viruses Further Aspects TAXONOMIC STUDY OF ANTIBIOTIC-PRODUCING MARINE ACTINOBACTERIA Introduction Materials and Methods Result Discussion Conclusion MARINE CYANOBACTERIA: A PROLIFIC SOURCE OF BIOACTIVE NATURAL PRODUCTS AS DRUG LEADS Introduction Bioactive Secondary Metabolites from Marine Cyanobacteria Conclusions MARINE BACTERIA ARE AN ATTRACTIVE SOURCE TO OVERCOME THE PROBLEMS OF ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS AUREUS Introduction Strategies for Overcoming Antibiotic Resistance of Bacteria Marine Bacteria Are Attractive Natural Sources for Overcoming Antibiotic Resistance of MRSA MARINE BACTERIA AS PROBIOTICS AND THEIR APPLICATIONS IN AQUACULTURE Introduction Definition of Probiotics in Aquaculture Selecting and Developing Probiotics in Aquaculture Effects of Probiotics on Aquatic Organisms Probiotics in the Larviculture 1 Problems Associated with Probiotics Development Further Work and Conclusions SMALL-MOLECULE ANTIBIOTICS FROM MARINE BACTERIA AND STRATEGIES TO PREVENT REDISCOVERY OF KNOWN COMPOUNDS Antibiotic Activity of Marine Bacteria Structurally Elucidated Marine Bacterial Antibiotics Cosmopolitan Antibiotics: the Rediscovery Problem Future Strategies for the Discovery of Marine Bacterial Antibiotics Conclusions and Perspectives MARINE BACTERIOPHAGES FOR THE BIOCONTROL OF FISH AND SHELLFISH DISEASES Introduction Mode of Action of Phages Diversity of Marine Phages Application of Marine Phages to Control Fish and Shellfish Diseases Potentials and Limitations of Phage Therapy in Marine Fish and Shellfish MARINE ACTINOMYCETES AS SOURCE OF PHARMACEUTICALLY IMPORTANT COMPOUNDS Introduction Marine Actinomycetes as Source of Therapeutics Marine Actinomycete Compounds as Antibacterials Marine Actinomycete Compounds as Antitumors/Antiproliferative Marine Actinomycete Enzymes as Antiproliferatives Marine Actinomycete Compounds as Antimalarials Marine Actinomycete Compounds as Antifungals Bioactive Compounds from Sponge-Associated Actinomycetes Conclusion ANTIMICROBIAL AGENTS FROM MARINE CYANOBACTERIA AND ACTINOMYCETES Introduction Antimicrobials from Marine Actinomycetes Antimicrobials from Marine Cyanobacteria Current Research Status: Challenges and Future Prospects Conclusions BIOACTIVE COMPOUNDS FROM MARINE ACTINOMYCETES Introduction Actinomycetes Diversity and Distribution of Marine Actinobacteria Bioactive Compounds Conclusions FUNGAL BIOACTIVE GENE CLUSTERS: A MOLECULAR INSIGHT Introduction to Fungal Secondary Metabolites Polyketide Synthase Nonribosomal Peptide Synthetase PKS and NRPS Products Conclusions ANTICANCER POTENTIALS OF MARINE-DERIVED FUNGAL METABOLITES Introduction Marine Fungi Cancer: Initiation, Progression, and Therapeutics Anticancer Metabolites of Marine Fungal Origin Future Prospects and Concluding Remarks ANTIFUNGAL AND ANTIMYCOTOXIN ACTIVITIES OF MARINE ACTINOMYCETES AND THEIR COMPOUNDS Introduction Diversity of Actinomycetes in the Sea Diversity of Natural Compounds from Marine Actinomycetes Biological Activities Conclusions ANTITUBERCULOSIS MATERIALS FROM MARINE MICROBES Introduction Marine Microbe-Derived Antituberculosis Agents Conclusions HARNESSING THE CHEMICAL
Professor Se-Kwon Kim, PhD, currently serves as a senior professor in the Department of Chemistry and the director of the Marine Bioprocess Research Center (MBPRC) at Pukyong National University in the Republic of Korea. He received his BSc, MSc, and PhD from the Pukyong National University and joined as a faculty member. He has previously served as a scientist in the University of Illinois, Urbana Champaign, Illinois (1988 - 1989), and was a visiting scientist at the Memorial University of Newfoundland in Canada (1999 - 2000). Professor Se-Kwon Kim was president of the Korean Society of Chitin and Chitosan (1986 - 1990) and the Korean Society of Marine Biotechnology (2006 - 2007). He was also the chairman for the 7th Asia-Pacific Chitin and Chitosan Symposium, which was held in South Korea in 2006. He is one of the board members of the International Society of Marine Biotechnology and the International Society for Nutraceuticals and Functional Foods. Moreover, he was the editor in chief of the Korean Journal of Life Sciences (1995 - 1997), the Korean Journal of Fisheries Science and Technology (2006 - 2007), and the Korean Journal of Marine Bioscience and Biotechnology (2006 - present). His research has been credited with the best paper award from the American Oil Chemist's Society (AOCS) and the Korean Society of Fisheries Science and Technology in 2002. Professor Se-Kwon Kim's major research interests are investigation and development of bioactive substances derived from marine organisms and their application in oriental medicine, nutraceuticals, and cosmeceuticals via marine bioprocessing and mass- production technologies. He has also conducted research on the development of bioactive materials from marine organisms for applications in oriental medicine, cosmeceuticals, and nutraceuticals. To date, he has authored over 500 research papers and holds 110 patents. In addition, he has written or edited more than 40 books.
Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues. Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.

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