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<p>Contributors, ix</p> <p>Foreword, xii</p> <p>Preface, xiv</p> <p>Acknowledgements, xv</p> <p>1 Clinical assessment of the adult patient with possible liver disease: history and physical examination, 1<br /> <i>Eberhard L. Renner</i></p> <p>2 Initial diagnosis, workup, and assessment of severity of liver disease in adults, 13<br /> <i>Scott K. Fung</i></p> <p>3 Pediatric liver disease: an approach to diagnosis and assessment of severity, 31<br /> <i>Binita M. Kamath and Vicky L. Ng</i><br /> <br /> 4 Natural history of the cirrhotic patient, 45<br /> <i>Jordan J. Feld</i></p> <p>5 Management of complications of portal hypertension in adults and children: variceal hemorrhage, 63<br /> <i>E. Jenny Heathcote, Simon Ling, and Binita M. Kamath</i></p> <p>6 Management of ascites, 80<br /> <i>David K.H. Wong</i></p> <p>7 Masses in the liver, 93<br /> <i>Morris Sherman</i></p> <p>8 Chronic portosystemic encephalopathy and its management, 112<br /> <i>Leslie B. Lilly and Binita M. Kamath</i></p> <p>9 Indications for liver transplantation in adults and children, 119<br /> <i>Nazia Selzner and Vicky L. Ng</i></p> <p>10 Management of fulminant hepatic failure, 132<br /> <i>Leslie B. Lilly</i></p> <p>11 Management of the complications of liver transplantation, 142<br /> <i>Eberhard L. Renner and Eve A. Roberts</i></p> <p>12 Acute viral hepatitis in adults and children: hepatitis A, B, C, D, E, and others, 162<br /> <i>Hemant A. Shah and Eve A. Roberts</i></p> <p>13 Chronic viral hepatitis in adults and children: hepatitis B, 185<br /> <i>Jordan J. Feld</i></p> <p>14 Chronic viral hepatitis in adults and children: hepatitis C, 208<br /> <i>Eberhard L. Renner and Eve A. Roberts</i></p> <p>15 Liver disease due to alcohol, 226<br /> <i>Nazia Selzner</i></p> <p>16 Drug-induced liver disease, 235<br /> <i>Leslie B. Lilly</i></p> <p>17 Obesity and its hepatic complications in adults and children, 244<br /> <i>E. Jenny Heathcote and Eve A. Roberts</i></p> <p>18 HIV-associated liver diseases, 263<br /> <i>David K.H. Wong</i></p> <p>19 Autoimmune hepatitis in adults and children, 281<br /> <i>Gideon M. Hirschfield</i></p> <p>20 Chronic cholestatic liver disease and its management in adults and children, 297<br /> <i>Gideon M. Hirschfi eld and Binita M. Kamath</i></p> <p>21 Vascular diseases of the liver, 315<br /> <i>Jordan J. Feld</i></p> <p>22 Approach to metabolic and storage diseases, 329<br /> <i>Hemant A. Shah and Eve A. Roberts</i></p> <p>23 Wilson disease: when should you think of Wilson disease?, 352<br /> <i>Eve A. Roberts and Gideon M. Hirschfield</i><br /> <br /> 24 Liver disease in pregnant women, 367<br /> <i>E. Jenny Heathcote</i></p> <p>25 Cystic disease of the liver, 383<br /> <i>Morris Sherman</i></p> <p>26 An internist’s approach to radiologic examination of the liver, 396<br /> <i>Anthony E. Hanbidge and Korosh Khalili</i></p> <p>Index, 413</p>

<p><strong>Dr. Jenny Heathcote</strong>, MB.BS, M.D, FRCP, FRCP, is Professor of Medicine at the?University of Toronto. She graduated from the Royal Free Hospital School of Medicine, London, UK in 1968. After completing internship and residency in internal medicine, she moved to Stanford, USA for further research training and joined the Toronto Western Hospital, where she has since built up an internationally recognized clinical liver research unit with a major interest in viral hepatitis and autoimmune liver disease. She is a Senior Scientist in the Toronto Western Research Institute where she is Division Head of "Patient Based Clinical Research".<br />Dr. Heathcote has been a Professor at the University of Toronto since 1995, winning numerous awards in a stellar career, including:?Queen's Jubilee Medal for services to hepatology;?Canadian Liver Foundation Gold Medal at the Canadian Digestive Diseases Week in 2004; the Canadian Liver Foundation Lifetime Achievement Award 2004; American Association for the Study of Liver Diseases Distinguished Achievement Award 2005;?International Sheila Sherlock Award from the Falk Foundation 2006.<br />She was funded from 2003 — 2009 by the Canadian?Institutes of Health Research, and was Director of the CIHR funded National Canadian Research Training Program in Hepatitis C. She now heads up the NIH funded Toronto site for the North American Clinical network for chronic hepatitis B.<br />She has published over 200 papers in the area of autoimmune liver disease and chronic viral hepatitis.

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