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<p><i>Contributors, viii</i></p> <p><i>Foreword, xiv</i></p> <p><i>Preface, xv</i></p> <p><i>About the companion website, xvi</i></p> <p><b>Part 1: Gastrointestinal Diseases and Disorders: The Public Health Perspective</b></p> <p>1 The Burden of Gastrointestinal and Liver Disease Around the World, 3<br /> Hannah P. Kim, Seth D. Crockett, & Nicholas J. Shaheen</p> <p><b>Part 2: How to Critically Read the Gastrointestinal Epidemiology Literature</b></p> <p>Introduction and Overview, 17<br /> Joe West</p> <p>2 How to Read a Cohort Study, 18<br /> Laila J. Tata</p> <p>3 How to Read a Case-Control Study, 30<br /> Joe West, Laila J. Tata, & Timothy R. Card</p> <p>4 How to Read a Randomized Controlled Clinical Trial, 39<br /> Matthew J. Grainge</p> <p>5 How to Read a Systematic Review and Meta-Analysis, 48<br /> Alexander C. Ford & Paul Moayyedi</p> <p>6 How to Decide if Any of This Matters, 58<br /> Kate M. Fleming & Timothy R. Card</p> <p><b>Part 3: How to Do Clinical Research in GI</b></p> <p>7 How to Develop and Validate a GI Questionnaire, 67<br /> Enrique Rey & G. Richard Locke III</p> <p>8 How to Do Population-Based Studies and Survey Research, 75<br /> Sanjiv Mahadeva & Hematram Yadav</p> <p>9 How to Find and Apply Large Databases for Epidemiologic Research, 83<br /> Jonas F. Ludvigsson, Joe West, Jessica A. Davila, Timothy R. Card, & Hashem B. El-Serag</p> <p>10 How to Do Genetic and Molecular Epidemiologic Research, 98<br /> Yuri A. Saito</p> <p>11 Diagnostic Studies, 106<br /> Paul Moayyedi</p> <p>12 Randomized Controlled Trials, 113<br /> Paul Moayyedi & Richard H. Hunt</p> <p><b>Part 4: Epidemiology of Major GI Diseases</b></p> <p>13 Epidemiology of GERD, Barrett’s Esophagus and Esophageal Cancer, 121<br /> David Armstrong</p> <p>14 Epidemiology of Helicobacter Pylori Infection, Peptic Ulcer Disease and<br /> Gastric Cancer, 135<br /> Grigorios I. Leontiadis & Olof Nyr´en<br /> <br /> 15 Epidemiology of Dyspepsia, 158<br /> Alexander C. Ford & Nicholas J. Talley</p> <p>16 Epidemiology of Upper Gastrointestinal Bleeding, 172<br /> Colin J. Crooks, Joseph Sung, & Timothy R. Card</p> <p>17 Epidemiology of Celiac Disease, 185<br /> Alberto Rubio-Tapia, Jonas F. Ludvigsson, & Joseph A. Murray</p> <p>18 Measuring Utilization of Endoscopy in Clinical Practice, 196<br /> Frances Tse & Alan Barkun</p> <p>19 Epidemiology of Colorectal Carcinoma, 213<br /> Harminder Singh, Joselito M. Montalban, & Salaheddin Mahmud</p> <p>20 Epidemiology of Irritable Bowel Syndrome, 222<br /> Rok Seon Choung & Yuri A. Saito</p> <p>21 Epidemiology of Constipation, 235<br /> Brian E. Lacy & John M. Levenick</p> <p>22 Epidemiology of Diverticular Disease, 249<br /> Robin Spiller & David Humes</p> <p>23 Epidemiology of Infectious Diarrhea, 262<br /> Christina M. Surawicz & Crenguta Stepan</p> <p>24 Epidemiology of Inflammatory Bowel Disease, 273<br /> Edward V. Loftus, Jr.</p> <p>25 Epidemiology of Fecal Incontinence, 285<br /> Adil E. Bharucha</p> <p>26 Epidemiology of Gallstones and Biliary Tract Cancers, 296<br /> Guy D. Eslick & Eldon A. Shaffer</p> <p>27 Epidemiology of Pancreatitis, 306<br /> Dhiraj Yadav, Santhi Swaroop Vege, & Suresh T. Chari</p> <p>28 Epidemiology of Pancreatic Cancer, 313<br /> Aravind Sugumar & Santhi Swaroop Vege</p> <p>29 Epidemiology of Hepatitis B and C in the United States, 322<br /> Sumeet K. Asrani & W. Ray Kim</p> <p>30 Epidemiology of Alcoholic Liver Disease, 332<br /> Sumeet K. Asrani & William Sanchez</p> <p>31 Epidemiology of Cirrhosis and Hepatocellular Carcinoma, 344<br /> Joe West & Guruprasad P. Aithal</p> <p>32 Epidemiology of Nonalcoholic Fatty Liver Disease (NAFLD), 357<br /> Guruprasad P. Aithal, Kshaunish Das, & Abhijit Chowdhury</p> <p>33 Epidemiology of Common Tropical GI Diseases, 373<br /> Magnus Halland, Rodney Givney, & Anne Duggan</p> <p>34 Nutritional Epidemiology and GI Cancers, 383<br /> Linda E. Kelemen & Ilona Csizmadi</p> <p>35 The Epidemiology of Obesity Among Adults, 394<br /> Cynthia L. Ogden, Brian K. Kit, Tala H.I. Fakhouri, Margaret D. Carroll, & Katherine M. Flegal</p> <p><i>Index 405</i></p>

<p>“With the exception of minor quibbles, this book represents the best and most up up-to-date summary of GI epidemiology currently available.”  (<i>Gastroenterology</i>, 1 October 2014)</p> <p> </p>

<p><b>Nicholas J. Talley</b>, University of Newcastle, Callaghan, NSW, Australia<br /><br /><b>G. Richard Locke III</b>, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine,<br />Rochester, MN, USA</p> <p><b>Paul Moayyedi</b>, McMaster University, Hamilton, ON, Canada</p> <p><b>Joe West</b>, Leeds Teaching Hospital Trust, University of Nottingham, Nottingham, UK</p> <p><b>Alexander C. Ford</b>, Leeds General Infirmary, Leeds, UK</p> <p><b>Yuri A. Saito</b>, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA</p>

<p>Identifying how, why and in whom gastrointestinal disease occurs, and what can be done to prevent it, is of key importance for the modern-day gastroenterologist and researcher.</p> <p>Brought to you by the world’s leading gastroenterologists, the second edition of <i>GI Epidemiology: Diseases and Clinical Methodology</i> is the only book that combines detailed analysis of the epidemiology of GI disease with a study of the methodology of clinical research.</p> <p>With a much greater clinical focus on the diagnostic and management approach for each disease than<br /> before, all existing chapters are fully updated with the very latest in statistical and clinical data. In addition, the revised edition contains several significant improvements, notably:</p> <p>• Five extra disease epidemiology chapters: Upper GI Bleeding; Hepatitis B and C; Common Tropical GI<br /> Diseases; Nutritional Epidemiology and GI Cancers; and Obesity among Adults</p> <p>• More illustrations, including maps of each disease</p> <p>• A more international focus with the inclusion of two experienced European editors</p> <p>• MCQs, summary checklists and key points throughout</p> <p>• Ten extra online-only chapters on methodological issues related to GI epidemiology such as Patient reported</p> <p><i>GI Epidemiology: Diseases and Clinical Methodology, 2nd Edition</i> is the perfect reference tool for gastroenterologists involved in both patient management and clinical research, and also for epidemiologists involved specifically in GI disease data and more general epidemiological studies.</p> <p><b>Titles of Related Interest</b></p> <p><i>Yamada’s Handbook of Gastroenterology, 3rd Edition</i><br /> Yamada; ISBN 9780470656204</p> <p><i>Essentials of Gastroenterology</i><br /> Friedman; ISBN 9780470656259</p>

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