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<p><i>Contributor List ix</i></p> <p><i>Series Foreword xiii</i></p> <p><i>Preface xv</i></p> <p><b>Part I: Epilepsy Basics</b></p> <p>1 Recognizing Seizures and Epilepsy: Insights from Pathophysiology 3<br /> Carl E. Stafstrom</p> <p>2 Classifying Epileptic Seizures and the Epilepsies 10<br /> Valeria M. Muro and Mary B. Connolly</p> <p>3 What Causes Epilepsy? 15<br /> Anna Rosati and Renzo Guerrini</p> <p>4 Epidemiology of Seizures and Epilepsy 28<br /> Aidan Neligan and Josemir W. Sander</p> <p><b>Part II: Working up Seizures and Epilepsy</b></p> <p>5 Diagnosing and Localizing Seizures at the Bedside and in Clinic 35<br /> Joseph I. Sirven</p> <p>6 Psychogenic Nonepileptic Episodes 42<br /> Vaishali S. Phatak</p> <p>7 What Can the EEG Tell Us? 45<br /> Mark Quigg</p> <p>8 What Can Neuroimaging Tell Us? 54<br /> Edward J. Novotny</p> <p>9 Workup of New-Onset Seizures 61<br /> Jennifer Langer</p> <p>10 Evaluation of the Patient with Medically Refractory Epilepsy 67<br /> Gregory L. Holmes</p> <p><b>Part III: Using Antiepileptic Medications</b></p> <p>11 Choosing, Initiating, Adjusting, and Changing Antiepileptic Medications 77<br /> John W. Miller</p> <p>12 Antiepileptic Drug Adverse Effects: What to Watch Out For 84<br /> Jacquelyn L. Bainbridge and Caleb Y. Oh</p> <p>13 Antiepileptic Drug Interactions 91<br /> Philip N. Patsalos</p> <p>14 Recognizing Intractability to Antiepileptic Medication 102<br /> Bassel W. Abou-Khalil</p> <p>15 Optimizing Antiepileptic Drug Therapy in Refractory Epilepsy 107<br /> Nicholas P. Poolos</p> <p>16 Rescue Medications for Home Treatment of Acute Seizures 112<br /> Peter Wolf and Rûta Mameniškienë</p> <p>17 When and How to Stop Antiepileptic Drugs 118<br /> John D. Hixson</p> <p>18 Using Parenteral Antiepileptic Medications 122<br /> Jane G. Boggs</p> <p>19 Pharmacopeia 126<br /> Gail D. Anderson</p> <p><b>Part IV: Special Topics in Pediatric Epilepsy</b></p> <p>20 Seizures in the Neonate 141<br /> Adam L. Hartman and Frances J. Northington</p> <p>21 Benign and Malignant Childhood Epilepsies 147<br /> Katherine C. Nickels and Elaine C. Wirrell</p> <p>22 Epilepsy: When to Perform a Genetic Analysis 159<br /> Heather E. Olson and Annapurna Poduri</p> <p>23 Metabolic Disorders Not to Miss 167<br /> Phillip L. Pearl and Yuezhou Joe Yu</p> <p><b>Part V: Special Topics in Adult Epilepsy</b></p> <p>24 Juvenile Myoclonic Epilepsy and Other Primary Generalized Epilepsies 177<br /> Shahin Hakimian</p> <p>25 Epilepsy in Women of Childbearing Age 184<br /> Autumn Klein</p> <p>26 Epilepsy After Sixty 189<br /> Edward Faught</p> <p><b>Part VI: What can be done when medication doesn’t work?</b></p> <p>27 When Should Epilepsy Neurosurgery Be Considered, and What Can It Accomplish? 199<br /> Paul A. Garcia</p> <p>28 When Should Vagus Nerve Stimulation Be Considered, and What Can It Accomplish? 205<br /> Pearce J. Korb and Sandra L. Helmers</p> <p>29 Ketogenic Diet and Alternative Therapies 210<br /> Dana Ekstein and Steven C. Schachter</p> <p><b>Part VII: How are acute seizures and status epilepticus evaluated and treated in the emergency department and the hospital?</b></p> <p>30 acute Symptomatic Seizures in Children and Adults: Evaluation and Treatment 217<br /> J. Stephen Huff and Jessica L. Carpenter</p> <p>31 Evaluating and Treating Status Epilepticus 222<br /> Jeffrey Bolton and Howard P. Goodkin</p> <p>32 Recognizing, Assessing, and Treating Seizures and Status Epilepticus in the ICU 227<br /> Nicolas Gaspard and Lawrence J. Hirsch</p> <p><b>Part VIII: The morbidity and mortality of epilepsy</b></p> <p>33 mortality in Epilepsy 243<br /> Elizabeth J. Donner</p> <p>34 Accidents in Epilepsy 248<br /> Allan Krumholz and Ana M. Sanchez</p> <p>35 Medical Comorbidity in Epilepsy 253<br /> Kimberly L. Pargeon and Sheryl R. Haut</p> <p>36 Cognitive Effects of Chronic Epilepsy 260<br /> Daniel L. Drane</p> <p>37 Recognizing and Treating Psychiatric Comorbidity in Epilepsy 268<br /> Jay Salpekar</p> <p><i>Index 275</i></p> <p><b>Color plate section between pages 80 and 81</b></p>

<p><b>John W. Miller</b>, MD, PhD, University of Washington, Seattle, WA, USA</p> <p><b>Howard P. Goodkin</b>, MD, PhD, University of Virginia, Charlottesville, VA, USA</p>

<p><b>Epilepsy is common but complex<br /> <br /> </b>Epilepsy is a complicated neurological condition with variable manifestations, numerous etiologies, and a diverse range of treatments. It is a chronic disease that, in many cases, can be controlled. However, treatment requires accurate clinical evaluation to allow intelligent treatment choices. </p> <p><i>Epilepsy</i> has been designed to help you develop these evaluation skills. Expert neurologists have distilled the evidence and combined their experience. They provide practical guidance to: </p> <ul> <li>The causes and classification of epilepsy</li> <li>Working up seizures</li> <li>Antiepileptic medications</li> <li>Pediatric epilepsy</li> <li>Adult epilepsy</li> <li>Emergency epilepsy</li> <li>Comorbidity and mortality of epilepsy</li> </ul> <p>Clinical in approach, practical in execution, <i>Epilepsy</i> is packed with tricks, tips, and focused advice to help you better manage your patients’ seizures.</p>

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