Details

Detection of Highly Dangerous Pathogens


Detection of Highly Dangerous Pathogens

Microarray Methods for BSL 3 and BSL 4 Agents
1. Aufl.

von: Tanja Kostic, Patrick Butaye, Jacques Schrenzel

58,99 €

Verlag: Wiley-Blackwell
Format: PDF
Veröffentl.: 29.04.2009
ISBN/EAN: 9783527626694
Sprache: englisch
Anzahl Seiten: 191

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Beschreibungen

Written by leading experts in the field as part of an interdisciplinary pan-European research program funded by the EU, the results provided in this booklet provide a unique and comprehensive overview of how microarray technology can be used in safely tracking the most highly dangerous pathogens. A must-have for public health agencies focused on bioterrorism as well as all laboratories working with BSL3 and/or BSL 4 agents.
Preface (Kostic, Butaye, Schrenzel)<br /> Introduction on Microarray-based Detection Methods (Schrenzel, Kostic, Bodrossy, Francois)<br /> METHODS<br /> Long-oligonucleotide Microarray-based Microbial Detection (Kostic, Bodrossy)<br /> Sequence-specific End-labelling of Oligonucleotides (SSELO) (Kostic, Bodrossy)<br /> Non-cognate Approaches for Pathogen Detection on Microarrays (Schrenzel, Francois, Hernandez, Hibbs, Huyghe, Charbonnier)<br /> Patterning Techniques for Array Platforms (Piskin, Garipcan, Demirel, Caglayan)<br /> Probe Immobilization Techniques in Array Technologies (Piskin, Caglayan, Duman)<br /> IDENTIFICATION <br /> Low-Cost-and-Density (LCD)-Microarrays - a Novel Technique for Identification and Typing of Microorganisms (Frangoulidis, Heiser, Landt, Meyer)<br /> DNA Microarray Technique for Detection and Identification of Viruses Causing Encephalitis and Hemorrhagic Fever (Nordstroem, Falk, Nilsson, Lundkvist)<br /> Microarrays for genomotyping of pathogens (Kieboom, Voskamp, Broekhuijsen)<br /> TYPING <br /> Single Nucleotide Polymorphisms (SNPs) as Targets for DNA-array Based Identification and Typing of BSL3 Bacteria (Wattiau, Vos, Fretin)<br /> Use of a Microchip to Detect Antibiotic Resistance Genes in Bacillus anthracis (Perreten, Frey)<br /> QUALITY CONTROL<br /> Progress Toward Development of Microarrays for Routine Diagnostic Use for Detection of Select High Risk Pathogens (Kempsell, Shah, Sherwin, Vipond, Silman)
"The book reads very well and includes many useful colour schematic diagrams and pictures. I would recommend this book to the researcher who is interested in getting into the microarray field." (<i>Microbiology Today</i>, November 2009)
Tania Kostic is a researcher in the Department of Bioresources/Microbiology at the Austrian Research Centers at Seibersdorf working on microbial diagnostic microarrays. <br /> <br /> Patrick Butaye is a veterinary researcher at the Veterinary and Agrochemical Research Center in Brussels with a focus on antimicrobial resistance in bacteria from animal origin. <br /> <br /> Jacques Schrenzel is a physician and microbiologist, heading the central bacteriological laboratory of the Hôpitaux Universitaires de Genève. He is also a consultant for infectious diseases and is in charge of the genome research laboratory.

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