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<p>List of Contributors, vii</p> <p>Preface, x</p> <p><b>Section 1 Dermatology and Oncology</b></p> <p>1 Epidemiology and Burden of Disease, 3<br /><i>Beth N. McLellan, Devika Patel and Mario E. Lacouture</i></p> <p>2 The History of Supportive Oncodermatology, 17<br /><i>Yevgeniy Balagula, Steven T. Rosen and Mario E. Lacouture</i></p> <p>3 Structure and Function of the Integumentary System and the Dermatology Lexicon, 24<br /><i>Emmy Graber and Amit Garg</i></p> <p>4 Types of Dermatologic Reactions, 33<br /><i>Raed O. Alhusayen, Sandra R. Knowles and Neil H. Shear</i></p> <p>5 Grading Dermatologic Adverse Events in Clinical Trials Using CTCAE v4.0, 47<br /><i>Alice Chen, Asha Acharya and Ann Setser</i></p> <p>6 Psychosocial Issues in Oncology: Clinical Management of Psychosocial Distress, Health-Related Quality of Life, and Special Considerations in Dermatologic Oncology, 60<br /><i>Lynne I. Wagner and David Cella</i></p> <p>7 Dermatopathology, 69<br /><i>Molly A. Hinshaw and James L. Troy</i></p> <p><b>Section 2 Cancer-Related Dermatologic Disorders</b></p> <p>8 Paraneoplastic, Inherited Cancer Syndrome, and Environmental Carcinogen-Related Dermatoses, 77<br /><i>Cindy England Owen and Jeffrey P. Callen</i></p> <p><b>Section 3 Dermatologic Conditions During Cancer Therapy</b></p> <p>9 Oral Mucosal Complications of Cancer Therapy, 89<br /><i>Stephen T. Sonis</i></p> <p>10 Hair Disorders Associated with Anticancer Agents, 100<br /><i>Caroline Yeager and Elise A. Olsen</i></p> <p>11 Nail Abnormalities in Oncology Practice, 115<br /><i>Robert Baran, Bernard Fouilloux and Caroline Robert</i></p> <p>12 Pruritus, 122<br /><i>Tejesh Patel and Gil Yosipovitch</i></p> <p>13 Management Options for Hot Flashes in Cancer Patients, 131<br /><i>Amanda R. Moraska and Charles L. Loprinzi</i></p> <p><b>Section 4 Skin Toxicities to Chemotherapy</b></p> <p>14 Alkylating Agents, 147<br /><i>Elisabeth Livingstone, Lisa Zimmer, Larissa Leister and Dirk Schadendorf</i></p> <p>15 Antimetabolite Reactions, 160<br /><i>Emily Y. Chu and Heidi H. Kong</i></p> <p>16 Topoisomerase-Interacting Agents, 170<br /><i>Tomas Skacel, Roger von Moos and Reinhard Dummer</i></p> <p>17 Epidermal Growth Factor Receptor Inhibitor Reactions, 184<br /><i>Yevgeniy Balagula and Mario E. Lacouture</i></p> <p>18 Small Molecule Multikinase Inhibitors, 196<br /><i>Caroline Robert, Vincent Sibaud and Christine Mateus</i></p> <p>19 Antimicrotubule Agents, 208<br /><i>Claus Garbe</i></p> <p>20 Histone Deacetylase Inhibitors, Proteasome Inhibitors, Demethylating Agents, Arsenicals, and Retinoids, 215<br /><i>Najla Al-Dawsari, Shannon C. Trotter and Francine Foss</i></p> <p>21 Miscellaneous Reactions, 224<br /><i>Katharina C. Kaehler, Christine B. Boers-Doets, </i><i>Mario E. Lacouture and Axel Hauschild</i></p> <p>22 Skin Toxicities due to Biotherapy, 233<br /><i>Kathryn T. Ciccolini, Katharina C. Kaehler, Mario E. Lacouture and Axel Hauschild</i></p> <p>23 Monoclonal Antibodies, 241<br /><i>Caroline Robert</i></p> <p>24 Endocrine Agents, 248<br /><i>Katherine Szyfelbein Masterpol, Maura Dickler and Mario E. Lacouture</i></p> <p>25 Agents for the Management of Hematologic Reactions, 257<br /><i>Mee-young Lee and Caroline C. Kim</i></p> <p>26 Radiation-Induced Skin Reactions, 264<br /><i>Rebecca K.S. Wong and Zahra Kassam</i></p> <p>27 Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease, 281<br /><i>Stephanie W. Hu and Jonathan Cotliar</i></p> <p>28 Extravasation Reactions, 295<br /><i>Seppo W. Langer</i></p> <p>29 Topical Anticancer Therapies, 301<br /><i>Patricia L. Myskowski</i></p> <p>30 Life-threatening (Serious) Dermatologic Adverse Events, 310<br /><i>Milan J. Anadkat</i></p> <p>31 Dermatologic Infections, 319<br /><i>Yevgeniy Balagula, Mario E. Lacouture and James I. Ito</i></p> <p><b>Section 5 Late Cutaneous Events from Cancer Treatment</b></p> <p>32 Late Dermatologic Conditions, 339<br /><i>Jennifer Nam Choi</i></p> <p><b>Section 6 Dermatologic Practice in Oncology</b></p> <p>33 Management Algorithms for Dermatologic Adverse Events, 367<br /><i>Alyx Rosen, Iris Amitay-Laish and Mario E. Lacouture</i></p> <p>34 Dermatologic Therapeutics and Formulations, 384<br /><i>Judy H. Borovicka, Jennifer R.S. Gordon, Ann Cameron Haley, Nicole E. Larsen and Dennis P. West</i></p> <p>35 Dermatologic Techniques and Procedures, 401<br /><i>Robert Eilers Jr., Kishwer S. Nehal and Erica H. Lee</i></p> <p>36 Appearance-Related Concerns in the Cancer Patient, 410<br /><i>Amy J. Derick</i></p> <p>Index, 417</p>

<p><strong>Mario E. Lacouture</strong>, MD, is Associate Attending Dermatologist in the Department of Medicine at the Memorial Sloan-Kettering Cancer Center in New York City. He is a well recognized international authority on skin conditions in cancer patients, His clinical focus is the recognition and management of the side effects and conditions of the skin, hair, and nails that may arise in cancer patients and survivors as a consequence of surgery, chemotherapy, radiation, or transplantation. In 2012 published a well-received book for patients on this subject, <em>Dr. Lacouture's Skin Care Guide for People Living With Cancer</em> (Harborside Press).

<p><b>The first book focusing specifically on frequent and frequently disabling side effects involving the skin, hair and nails in cancer patients</b><br /> <br /> According to the World Health Organization, there are approximately thirty million people living with a diagnosis of cancer – the majority of whom will receive surgery, systemic therapy, and/or radiation, and who will suffer from dermatologic adverse events. Dermatologists and oncologists are only beginning to grapple with these events, which pose serious quality-of-life issues with so many patients, and will become more prevalent as survival rates improve, thanks in part to new cancer treatments and drug regimens.<br /> <br /> Concentrating on a topic that has only been briefly touched upon by other texts, this book offers a focused perspective on the clinical presentation, underlying pathophysiologic mechanisms, and management of skin, hair, and nail conditions for oncologists, dermatologists, and allied practitioners.<br /> <i>Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients:</i><br /> <br /> • Covers in detail the dermatologic adverse events of oncologic therapies, clinical presentations, and treatment recommendations<br /> <br /> • Enables dermatologists and other practitioners to significantly improve the care of patients with cancer<br /> • Addresses the dermatologic adverse events of cancer therapies used globally, of which a large number are found in developing countries<br /> <br /> • Emphasizes prophylactic measures – based on treatments used and type of cancer – to prevent the appearance of adverse events<br /> <br /> • Provides built-in discussions on patient education for practical counseling during therapies<br /> <br /> • Offers rapid-reference sections on topical dermatology drugs</p> <p>The first book to present dermatologic conditions in cancer patients and survivors in a uniform and in-depth manner, <i>Dermatologic Principles and Practice in Oncology</i> is ideal for oncologists, oncology nurses, and dermatologists who wish to take better care of those with adverse skin, hair, and nail conditions.</p>

SG