Details

Combinatorial Chemistry


Combinatorial Chemistry

A Practical Approach
Methods & Principles in Medicinal Chemistry, Band 9 1. Aufl.

von: Willi Bannwarth, Eduard Felder, Raimund Mannhold, Hugo Kubinyi, Hendrik Timmerman

147,99 €

Verlag: Wiley-VCH
Format: PDF
Veröffentl.: 14.08.2009
ISBN/EAN: 9783527614158
Sprache: englisch
Anzahl Seiten: 450

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Beschreibungen

As we enter the new millennium, combinatorial chemistry is providing significant impetus to new innovations in synthetic chemistry. Combinatorial chemistry has rapidly become the rising star among research methods, allowing scientists to efficiently test the feasibility of a multitude of new compounds.<br> The pursuit of new drugs is but one challenging field in which these combinatorial methods are particularly advantageous, helping researchers meet the modern-day demands of a highly competitive environment.<br> This book emphasises that modern combinatorial synthesis is possible not only in the solid phase, but also in solutions. Moreover, it discusses computer-assisted methods as well as the apparatus and instrumentation required for the combinatorial method. Successful and experienced researchers in the leading pharmaceutical companies and most renowned research institutes offer a solid insight and perspective into this diverse field.<br> A 'must' for every scientist in the area of pharmaceutical research
GENERAL INTRODUCTION<br> COMBINATORIAL CHEMISTRY IN SOLUTION<br> Introduction<br> Multicomponent Condensations<br> Purification in High Speed Solution-Phase Synthesis<br> SOLID-PHASE CHEMISTRY<br> Linkers for Solid-Phase Organic Synthesis and Combinatorial Approaches on Solid Support<br> Cyclative Cleavage: A Versatile Concept in Solid-Phase Organic Chemistry<br> C-C Bond Forming Reactions<br> Combinatorial Synthesis of Heterocycles<br> POLYMER SUPPORTED REAGENTS: PREPARATION AND USE IN PARALLEL ORGANIC SYNTHESIS<br> ENCODING STRATEGIES FOR COMBINATORIAL CHEMISTRY<br> DEVICES FOR COMBINATORIAL SYNTHESIS<br> COMPUTER-ASSISTED LIBRARY DESIGN
"...this book is recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope." (<i>Journal of the American Chemical Society</i>, Vol. 123, No. 35)
<p><b>Willi Bannwarth</b> is the editor of <i>Combinatorial Chemistry: A Practical Approach</i>, published by Wiley.</p> <p><b>Eduard Felder</b> is the editor of <i>Combinatorial Chemistry: A Practical Approach</i>, published by Wiley.</p>

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