Details

Biomaterials Surface Science


Biomaterials Surface Science


2. Aufl.

von: Andreas Taubert, Joao F. Mano, Jos¿ Carlos Rodr¿guez-Cabello

156,99 €

Verlag: Wiley-VCH
Format: PDF
Veröffentl.: 12.07.2013
ISBN/EAN: 9783527649631
Sprache: englisch
Anzahl Seiten: 616

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Beschreibungen

At the interface of biology, chemistry, and materials science, this book provides an overview of this vibrant research field, treating the seemingly distinct disciplines in a unified way by adopting the common viewpoint of surface science.<br> The editors, themselves prolific researchers, have assembled here a team of top-notch international scientists who read like a "who's who" of biomaterials science and engineering. They cover topics ranging from micro- and nanostructuring for imparting functionality in a top-down manner to the bottom-up fabrication of gradient surfaces by self-assembly, from interfaces between biomaterials and living matter to smart, stimuli-responsive surfaces, and from cell and surface mechanics to the elucidation of cell-chip interactions in biomedical devices. As a result, the book explains the complex interplay of cell behavior and the physics and materials science of artificial devices.<br> Of equal interest to young, ambitious scientists as well as to experienced researchers.
PART I: Polymer Surfaces<br> <br> POLYMERS FOR SURFACE STRUCTURING <br> Introduction <br> Structuring and Modification of Interfaces by Self-Assembling Proteins <br> Structuring and Modification of Solid Surfaces via Printing of Biomolecules <br> Conclusion and Outlook <br> <br> SURFACE-GRAFTED POLYMER BRUSHES <br> Introduction <br> Synthesis of Polymer Brushes<br> Stimuli-Responsive Polymer Brushes<br> Polyelectrolyte Brushes <br> Bio-Functionalized Polymer Brushes <br> <br> INHIBITING NONSPECIFIC PROTEIN ADSORPTION: MECHANISMS, METHODS, AND MATERIALS <br> Introduction <br> Fundamental Forces Leading to Nonspecific Protein Adsorption <br> Poly(Ethylene Glycol) <br> Surface Force Apparatus (SFA) <br> Applications of Poly(Ethylene Glycol) <br> Summary <br> <br> STIMULI-RESPONSIVE SURFACES FOR BIOMEDICAL APPLICATIONS <br> Introduction <br> Surface Modification Methodologies: How to Render Substrates with Stimuli Responsiveness <br> Exploitable Stimuli and Model Smart Biomaterials <br> Biomedical Applications of Smart Surfaces <br> Conclusions <br> <br> SURFACE MODIFICATION OF POLYMERIC BIOMATERIALS <br> Introduction <br> Effect of Material Surfaces on Interactions with Biological Entities<br> Surface Morphology of Polymeric Biomaterials <br> Surface Modifications to Improve Biocompatibility of Biomaterials <br> Surface Modifications to Improve Hemocompatibility of Biomaterials <br> Surface Modifications to Improve Antibacterial Properties of Biomaterials <br> Nanoparticles <br> <br> POLYMER VESICLES ON SURFACES <br> Introduction <br> Polymer Vesicles<br> Applications of Polymer Membranes and Vesicles as Smart and Active Surfaces <br> Current Limitations of Polymer Vesicles and Emerging Trends <br> Conclusions <br> <br> PART II: Hydrogel Surfaces <br> <br> PROTEIN-ENGINEERED HYDROGELS <br> Introduction to Protein Engineering for Materials Design <br> History and Development of Protein-Engineered Materials <br> Modular Design and Recombinant Synthesis Strategy <br> Processing Protein-Engineered Materials <br> Conclusion<br> <br> BIOACTIVE AND SMART HYDROGEL SURFACES <br> Introduction <br> Mimicking the Extracellular Matrix <br> Hydrogels: Why Are They So Special? <br> Elastin-Like Recombinamers as Bioinspired Proteins <br> Perspectives <br> <br> BIORESPONSIVE SURFACES AND STEM CELL NICHES <br> General Introduction <br> Stem Cell Niches <br> Surfaces as Stem Cell Niches <br> Conclusions <br> <br> PART III: Hybrid & Inorganic Surfaces <br> <br> MICRO- AND NANOPATTERNING OF BIOMATERIAL SURFACES<br> Introduction <br> Photolithography <br> Electron Beam Lithography<br> Focused Ion Beam <br> Soft Lithography <br> Dip-Pen Nanolithography <br> Nanoimprint Lithography <br> Sandblasting and Acid Etching <br> Laser-Induced Surface Patterning <br> Colloidal Lithography <br> Conclusions and Perspectives <br> <br> ORGANIC/INORGANIC HYBRID SURFACES <br> Introduction <br> Calcium Carbonate Surfaces and Interfaces<br> Calcium Phosphate Surfaces and Interfaces <br> Silica Surfaces and Interfaces <br> Conclusion and Outlook<br> <br> BIOACTIVE CERAMIC AND METALLIC SURFACES FOR BONE ENGINEERING <br> Introduction <br> Ceramics for Bone Replacement and Regeneration <br> Metallic Surfaces for Bone Replacement and Regeneration <br> Conclusions <br> <br> PLASMA-ASSISTED SURFACE TREATMENTS AND MODIFICATIONS FOR BIOMEDICAL APPLICATIONS <br> Introduction <br> Surface Requisites for Biomedical Applications <br> Surface Functionalization of Inorganic Surfaces by Plasma Techniques <br> Applications of Plasma-Modified Surfaces in Biology and Biomedicine<br> Conclusions and Outlook <br> <br> BIOLOGICAL AND BIOINSPIRED MICRO- AND NANOSTRUCTURED DRY ADHESIVES <br> Introduction: Adhesion in Biological Systems <br> Fibrillar Contact Elements <br> Basic Physical Forces Contributing to Adhesion <br> Contact Mechanics <br> Larger Animals Rely on Finer Fibers <br> Peeling Theory <br> Artificial Adhesive Systems <br> Toward Smart Adhesives <br> <br> PART IV: Cell -<br> Surface Interactions <br> <br> GENERIC METHODS OF SURFACE MODIFICATION TO CONTROL ADHESION OF CELLS AND BEYOND <br> General Introduction <br> Survey on Generic Methods to Modify Material Surfaces <br> Results and Discussion <br> Summary and Conclusions <br> <br> SEVERE DEFORMATIONS OF MALIGNANT BONE AND SKIN CELLS, AS WELL AS AGED CELLS, ON MICROPATTERNED SURFACES <br> Introduction <br> Experimental Methods <br> The Interaction of Bone Cells with Micropillars <br> The Deformation of Skin Cells as a Function of Their Malignancy <br> The Deformation of Fibroblasts of Different Cellular Ages <br> Discussion <br> Conclusions <br> <br> THERMORESPONSIVE CELL CULTURE SURFACES DESIGNED FOR CELL-SHEET-BASED TISSUE ENGINEERING AND REGENERATIVE MEDICINE <br> Introduction <br> Characteristics of PIPAAm-Grafted Cell Culture Surfaces <br> Mechanisms of Cell Detachment from the Thermoresponsive Cell Culture Dish <br> Cell-Sheet-Based Tissue Engineering and Its Clinical Applications <br> Next-Generation Thermoresponsive Cell Culture Dishes <br> Conclusions<br> <br> CELL MECHANICS ON SURFACES <br> Introduction <br> What is Elasticity and Stiffness? <br> Measuring and Quantifying Stiffness <br> Controlling Substrate Stiffness <br> Naturally Derived Scaffolds <br> Synthetic Scaffolds <br> Substrate Stiffness - Impact on Cell Behavior <br> When Stiffness In vivo Goes Awry: the Impact of Fibrosis on Function <br> Novel Surface Fabrication Techniques to Improve Biomimicry <br> Conclusion <br> <br> ELECTRODE -<br> NEURAL TISSUE INTERACTIONS: IMMUNE RESPONSES, CURRENT<br> TECHNOLOGIES, AND FUTURE DIRECTIONS <br> Introduction <br> Immune Response to Neural Implants <br> Past and Current Neural Interfaces <br> Methods for Improvement of the Electrode -<br> Tissue Interface <br> Conclusions and Future Directions <br> <br> INDEX <br>
Andreas Taubert is Professor of Supramolecular Chemistry at the University of Potsdam, Germany. After his PhD at the Max-Planck-Institute for Polymer Research in Mainz he was a postdoc at the University of Pennsylvania, USA, and then a group leader at the University of Basel, Switzerland. His research interests are bioinspired hybrid materials and materials chemistry with ionic liquids.<br> <br> Joao F. Mano is Professor at the University of Minho, Portugal, and staff member of the 3B's research group Biomaterials, Biodegradables and Biomimetics. His research interests include the development of new materials and concepts for biomedical applications. He was awarded the Stimulus to Excellence by the Portuguese Minister for Science and Technology in 2005 and the Materials Science and Technology Prize by the Federation of European Materials Societies in 2007.<br> <br> Jose Carlos Rodriguez-Cabello is Professor at the University of Valladolid, Spain, and head of the research group "Biomaterials, Biomimicry, Nanobiotechnology". His research is focused on design, biosynthesis and characterization of advanced, multifunctional genetically engineered protein-polymers. In 2009, he received the "Campus Emprende" Award in the category of business venture for a project on new materials for biomedical applications.<br>
<p>At the interface of biology, chemistry, and materials science, this book provides an overview of this vibrant research field, treating the seemingly distinct disciplines in a unified way by adopting the common viewpoint of surface science.</p> <p>The editors, themselves prolific researchers, have assembled here a team of top-notch international scientists who read like a "who's who" of biomaterials science and engineering.They cover topics ranging from micro- and nanostructuring for imparting functionality in a top-down manner to the bottom-up fabrication of gradient surfaces by self-assembly, from interfaces between biomaterials and living matter to smart, stimuli-responsive surfaces, and from cell and surface mechanics to the elucidation of cell-chip interactions in biomedical devices. As a result, the book explains the complex interplay of cell behavior and the physics and materials science of artificial devices.</p> <p>Of equal interest to young, ambitious scientists as well as to experienced researchers.</p>

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