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<b>Part 1: Pharmacology</b>. <p>1 Pharmacokinetic principles.</p> <p><i>Michel MRF Struys, Alain Kalmar and Peter De Paepe</i>.</p> <p>2 Pharmacodynamics.</p> <p><i>Susan Hill</i>.</p> <p>3 Pharmacogenomics.</p> <p><i>Amr Mahdy</i>.</p> <p>4 Receptors and second messenger systems.</p> <p><i>Thomas Engelhardt.</i></p> <p>5 Anaphylaxis.</p> <p><i>Michael Rose and Malcolm Fisher</i>.</p> <p>6 Refl ections on chirality.</p> <p><i>Daniel Burke</i>.</p> <p>7 Ion channels.</p> <p><i>George Lees, Leanne Coyne and Karen M. Maddison</i>.</p> <p>8 Immunosuppression.</p> <p><i>Roxanna Bloomfield and David Noble</i>.</p> <p>9 Mechanisms of anaesthesia: a role for voltage-gated K channels?.</p> <p><i>Peter Århem, Kristoffer Sahlholm and Johanna Nilsson</i>.</p> <p>10 Use and abuse of antibiotics.</p> <p><i>Jeremy Cohen and Jeffrey Lipman</i>.</p> <p><b>Part 2: Physiology</b>.</p> <p>11 Infl ammation and immunity.</p> <p><i>Helen F. Galley</i>.</p> <p>12 Shock: pathogenesis and pathophysiology.</p> <p><i>Anand Kumar</i>.</p> <p>13 Cellular physiology.</p> <p><i>Nigel R. Webster</i>.</p> <p>14 Acid–base balance: albumin and strong ions.</p> <p><i>John A. Kellum</i>.</p> <p>15 Fluids and electrolytes.</p> <p><i>Martin Kuper and Neil Soni</i>.</p> <p>16 The microcirculation.</p> <p><i>Bryce Randalls</i>.</p> <p>17 Respiratory physiology at the molecular level.</p> <p><i>Andrew Lumb</i>.</p> <p>18 Non-respiratory functions of the lung.</p> <p><i>Andrew Lumb and Susan Walwyn</i>.</p> <p>19 The brain as a site of infl ammation after acute injury.</p> <p><i>Jonathan Rhodes and Peter Andrews.</i></p> <p>20 Heart failure.</p> <p><i>Sze-Yuan Ooi, Christopher Pepper and Stephen Ball</i>.</p> <p>21 The hormonal and metabolic response to anaesthesia, surgery and trauma.</p> <p><i>Grainne Nicholson and George M. Hall</i>.</p> <p>22 Temperature regulation.</p> <p><i>Anita Holdcroft</i>.</p> <p>23 Theories of pain.</p> <p><i>Lesley Colvin</i>.</p> <p>24 Neuromuscular transmission and function.</p> <p><i>Andrew D. Axon and Jennifer M. Hunter</i>.</p> <p><b>Part 3: Clinical measurement</b>.</p> <p>25 Magnetic resonance imaging.</p> <p><i>Fiona J. Gilbert and Thomas W. Redpath.</i></p> <p>26 Nanotechnology.</p> <p><i>The Nanotechnology Study Group, University of Aberdeen</i>.</p> <p>27 Assessment of the cardiovascular system.</p> <p><i>Charles S. Reilly</i>.</p> <p>28 Assessment of respiratory function.</p> <p><i>Stuart Murdoch</i>.</p> <p>29 Monitoring the depth of anaesthesia.</p> <p><i>Praveen Kalia</i>.</p> <p>30 Research study design.</p> <p><i>John Robert Sneyd</i></p>

<b>Nigel Webster</b> graduated in Medicine from Leeds University in 1977 and obtained his PhD in 1985. He was appointed to the Chair in Anaesthesia & Intensive Care at the University of Aberdeen, in 1994. Professor Webster has an extensive publication record in inflammatory and immune responses in the critically ill. He reviews for a number of basic science, anaesthesia and critical care journals and is an Editorial Board member for the British Journal of Anaesthesia and Critical Care Medicine. <br /> <p><b>Helen Galley</b> obtained her PhD from the University of Leeds in 1989. She was appointed to the post of Lecturer in Anaesthesia & Intensive Care at the University of Aberdeen in 1995 and was promoted to Senior Lecturer in 2000. Dr Galley has published 60 research papers, 26 reviews/editorials/chapters and edited 12 books. Her research interests focus on inflammatory and immune responses in the critically ill. Dr Galley reviews for a number of basic science, anaesthesia and critical care journals and is a member of the Board of Management for the British Journal of Anaesthesia.</p>

<i>Anaesthesia Science</i> presents the scientific foundations upon which the clinical practice of anaesthesia and care of the critically ill are based. <br /> <p><br /> </p> <p>Written on the basis that basic science underlies the practice of anaesthesia, <i>Anaesthesia Science</i> provides detailed coverage on less well appreciated aspects of the subject, such as the microcirculation, multi-organ failure, and the theory of pain. The book thoroughly integrates the clinical practice of anaesthesia with basic sciences, providing all the information needed in one convenient source.<br /> Furthermore the contributors, who feature some of the world’s most eminent anaesthesiologists, consistently include salient features of the scientific foundations of anaesthesia in their discussions.<br /> </p> <p><br /> </p> <p><i>Anaesthesia Science</i> is based on the Fellowship of the Royal College of Anaesthetists (FRCA) syllabus and aimed at trainee anaesthetists preparing for the FRCA, the European Diploma of Anaesthesiology and other equivalent examinations.</p>

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