Details

<p>Dedication</p> <p>Contributors</p> <p>Preface</p> About the Editors <p><b>Section 1: The Gram-Positive Cell Wall<br /></b><i>Vincent A. Fischetti</i></p> <p>1 The Gram-Positive Cell Wall<br /> <i>Manfred Rohde<br /> </i><br /> 2 Surface Proteins on Gram-Positive Bacteria<br /> <i>Vincent A. Fischetti<br /> </i><br /> <b>Section 2: The Streptococcus<br /></b><i>Vincent A. Fischetti and Joseph J. Ferretti </i></p> <p><b>Group A Streptococci<br /> <br /> </b>3 Intracellular Invasion by Streptococcus pyogenes: Invasins, Host Receptors, and Relevance to Human Disease<br /> <i>Beinan Wang and P. Patrick Cleary<br /> </i><br /> 4 Capsular Polysaccharide of Group A Streptococci <br /> <i>Michael Wessels<br /> </i><br /> 5 Toxins and Superantigens of Group A Streptococci<br /> <i>Blake A. Shannon, John K. McCormick, and Patrick M. Schlievert<br /> </i><br /> 6 Genetics of Group A Streptococci<br /> <i>Kyu Hong Cho, Gary Port, and Michael Caparon<br /> </i><br /> 7 Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and Their Sequelae<br /> <i>Madeline W. Cunningham<br /> <br /> </i>8 Extracellular Matrix Interactions with Gram-Positive Pathogens<br /> <i>Sven Hammerschmidt, Manfred Rohde, and Klaus T. Preissner<br /> </i><br /> 9 Streptococcus-Mediated Host Cell Signaling<br /> <i>Vijay Pancholi<br /> </i><br /> 10 Vaccine Approaches to Protect Against Group A Streptococcal Pharyngitis<br /> <i>Vincent Fischetti<br /> </i><br /> 11 The Bacteriophages of Group A Streptococci<br /> <i>W. Michael McShan<br /> <br /> </i>12 Molecular Epidemiology, Ecology, and Evolution of Group A Streptococci<br /> <i>Debra E. Bessen, Pierre R. Smeesters, and Bernard W. Beall<br /> </i><br /> <b>Group B Streptococci<br /> </b><br /> 13 Surface Structures of Group B Streptococci Important to Human Immunity<br /> <i>Lawrence Paoletti and Dennis Kasper<br /> </i><br /> 14 Epidemiology of Group B Streptococcal Infections<br /> <i>Vanessa N. Raabe and Andi L. Shane<br /> </i><br /> <b>Group C and G Streptococci<br /> </b><br /> 15 Genetics and Pathogenicity Factors of Group C and G Streptococci<br /> <i>Horst Malke<br /> </i><br /> 16 Pathogenicity Factors in Group C and G Streptococci<br /> <i>Claire E. Turner, Laura Bubba, and Androulla Efstratiou<br /> </i><br /> 17 Infections Caused by Group C and G Streptococcus (Streptococcus dysgalactiae subsp. equisimilis and Others): Epidemiological and Clinical Aspects<br /><i>Gio Baracco</i></p> <p><b>Streptococcus pneumoniae<br /> </b><br /> 18 The Cell Wall of Streptococcus pneumoniae<br /> <i>Waldemar Vollmer, Orietta Massidda, and Alexander Tomasz<br /> </i><br /> 19 Streptococcus pneumoniae Capsular Polysaccharide<br /> <i>James Paton and Judy Morona<br /> </i><br /> 20  Streptococcus pneumoniae: Invasion and Inflammation<br /> <i>Allister J. Loughran, Carlos J. Orihuela, and Elaine I. Tuomanen<br /> </i><br /> 21 Phase Variation of Streptococcus pneumoniae<br /> <i>Jing Li and Jing-Ren Zhang <br /> </i><br /> 22 Genetics of Streptococcus pneumoniae<br /> <i>Francesco Santoro, Francesco Iannelli, and Gianni Pozzi<br /> </i><br /> 23 Pneumococcal Vaccines<br /> <i>David E. Briles, James C. Paton, Reshmi Mukerji, Edward Swiatlo, and Marilyn J. Crain<br /> </i><br /> <b>Enterococci<br /> </b><br /> 24 Pathogenicity of Enterococci<br /> <i>Elizabeth M. Selleck, Daria Van Tyne, and Michael S. Gilmore<br /> </i><br /> 25 Enterococcal Genetics<br /> <i>Keith E. Weaver<br /> </i><br /> <b>Oral Streptococci<br /> </b><br /> 26 Biology of Oral Streptococci<br /> <i>J. Abranches, L. Zeng, J. K. Kajfasz, S. R. Palmer, B. Chakraborty, Z. T. Wen, V. P. Richards, L. J. Brady, and J. A. Lemos<br /> </i><br /> 27 The Biology of Streptococcus mutans<br /><i>J. A. Lemos</i></p> <p>28 Genetics of Sanguinis-Group Streptococci in Health and Disease<br /> <i>Angela Nobbs and Jens Kreth<br /> </i><br /> <b>Lactococci<br /> </b><br /> 29 Genetics of Lactococci<br /> <i>Philippe Gaudu, Yuji Yamamoto, Peter Ruhdal Jensen, Karin Hammer, Delphine Lechardeur, and Alexandra Gruss<br /> </i><br /> <b>Section 3: The Staphylococcus<br /></b><i>Richard P. Novick<br /><br /></i>30 The Evolving Genome<br /><i>Jodi Lindsay</i></p> <p>31 Plasmids and Transposable and Integrative Elements<br /> <i>Neville Firth, Slade O. Jensen, Stephen M. Kwong, Ronald A. Skurray, and Joshua P. Ramsay<br /> </i><br /> 32 Temperate Phages of Staphylococcus aureus<br /> <i>Hanne Ingmer, David Gerlach, and Christine Wolz<br /> </i><br /> 33 Pathogenicity Islands and Their Role in Staphylococcal Biology<br /> <i>Richard Novick<br /> </i><br /> 34 Respiration and Small Colony Variants of Staphylococcus aureus<br /> <i>Richard Proctor<br /> </i><br /> 35 Noncoding RNA<br /> <i>Emma Desgranges, Stefano Marzi, Karen Moreau, Pascale Romby, and Isabelle Caldelari<br /> </i><br /> 36 The Staphylococcal Cell Wall<br /> <i>Rita Sobral and Alexander Tomasz<br /> </i><br /> 37 Staphylococcal Protein Secretion and Envelope Assembly<br /> <i>Olaf Schneewind and Dominique M. Missiakas<br /> </i><br /> 38 Surface Proteins Required for Adhesion and Invasion<br /> <i>Timothy J. Foster<br /> </i><br /> 39 Immune Evasion by Staphylococcus aureus<br /> <i>Nienke W. M. de Jong, Kok P. M. van Kessel, and Jos A. G. van Strijp<br /> </i><br /> 40 Staphylococcus aureus Secreted Toxins and Extracellular Enzymes<br /> <i>Victor J. Torres<br /> </i><br /> 41 Regulation of Staphylococcus aureus Virulence<br /> <i>Christian Jenul and Alexander R. Horswill<br /> </i><br /> 42 Virulence and Metabolism<br /> <i>Anthony R. Richardson<br /> </i><br /> 43 Staphylococcal Biofilms<br /> <i>Michael Otto<br /> </i><br /> 44 Fulminant Staphylococcal Infections<br /> <i>Yves Gillet, Thomas Henry, and Françios Vandenesch<br /> </i><br /> 45 Staphylococcus aureus Colonization of the Human Nose and Interaction with Other Microbiome Members<br /> <i>Claudia Laux, Andreas Peschel, and Bernhard Krismer<br /> <br /> </i>46 Staphylococcus aureus in Animals<br /> <i>Andreas F. Haag, J. Ross Fitzgerald, and José R. Penadés<br /> </i><br /> 47 Antibiotic Resistance and the MRSA Problem<br /> <i>Martin Vestergaard, Dorte Frees, and Hanne Ingmer<br /> </i><br /> 48 Immunity to Staphylococcus aureus: Implications for Vaccine Development<br /> <i>Richard A. Proctor<br /> </i><br /> 49 Nonconventional Therapeutics Against Staphylococcus aureus<br /> <i>Eric Skaar<br /> <br /> </i><b>Section 4: The Listeriae<br /></b><i>Daniel A. Portnoy</i></p> <p>50 Epidemiology and Clinical Manifestations of Listeria monocytogenes Infection<br /> <i>Walter F. Schlech III<br /> </i><br /> 51 Innate and Adaptive Immune Responses during Listeria monocytogenes Infection<br /> <i>Sarah E.F. D'Orazio<br /> </i><br /> 52 Regulation of Listeria monocytogenes Virulence<br /> <i>Jörgen Johannson and Nancy E. Freitag<br /> </i><br /> 53 The Cell Biology of Invasion and Intracellular Growth by Listeria monocytogenes<br /> <i>Javier Pizarro-Cerdá and Pascale Cossart<br /> </i><br /> 54 Metabolism of the Gram-Positive Bacterial Pathogen Listeria monocytogenes<br /> <i>John-Demian Sauer, Anat A. Herskovits, and Mary X. D. O’Riordan<br /> </i><br /> <b>Section 5: Spore-Forming Pathogens<br /></b><i>Julian I. Rood</i></p> <p>55 The Bacillus cereus Group: Bacillus Species with Pathogenic Potential<br /> <i>Monika Ehling-Sculz, Theresa M. Koehler, and Didier Lereclus<br /> </i><br /> 56 Sporulation and Germination in Clostridial Pathogens<br /> <i>Aimee Shen, Adrianne N. Edwards, Mahfuzur R. Sarker, and Daniel Paredes-Sabja<br /> </i><br /> 57 Clostridial Genetics: Genetic Manipulation of the Pathogenic Clostridia<br /> <i>Sarah A. Kuehne, Julian I. Rood, and Dena Lyras<br /> </i><br /> 58 Genomics of the Pathogenic Clostridia<br /> <i>Robert J. Moore and Jake A. Lacey<br /> </i><br /> 59 Virulence Plasmids of the Pathogenic Clostridia<br /> <i>Sarah A. Revitt-Mills, Callum J. Vidor, Thomas D. Watts, Dena Lyras, Julian I. Rood, and Vicki Adams<br /> </i><br /> 60 Enterotoxic Clostridia: Clostridium perfringens Enteric Diseases<br /> <i>Archana Shrestha, Francisco A. Uzal, and Bruce A. McClane<br /> </i><br /> 61 Enterotoxic Clostridia: Clostridioides difficile Infections<br /> <i>S. Mileto, A. Das, and Dena Lyras<br /> </i><br /> 62 Histotoxic Clostridial Infections<br /> <i>Mashahiro Nagahama, Masaya Takehara, and Julian I. Rood<br /> </i><br /> 63 Neurotoxigenic Clostridia<br /> <i>Eric A. Johnson<br /></i><b><br />Section 6: Mycobacteria and Corynebacteria<br /></b><i>Miriam Braunstein</i></p> <p>64 Mycobacteriophages<br /> <i>Graham F. Hatfull<br /> </i><br /> 65 Immunology of Mycobacterium tuberculosis Infections<br /> <i>Jonathan Kevin Sia and Jyothi Rengarajan<br /> </i><br /> 66 Unraveling the Structure of the Mycobacterial Envelope<br /><i>Mamadou Daffé and Hedia Marrakchi</i></p> <p>67 The Dream of a Mycobacterium<br /> <i>Catherine Baranowski, E. Hesper Rego, and Eric J. Rubin<br /> <br /> </i>68 Mycobacterium tuberculosis Metabolism<br /><i>Gabriel T. Mashabela1, Timothy J. de Wet, and Digby F. Warner </i></p> <p>69 Protein Export Into and Across the Atypical Diderm Cell Envelope of Mycobacteria<br /> <i>Vincent J.C. van Winden, Edith N.G. Houben, and Miriam Braunstein<br /> </i><br /> 70 Corynebacterium diphtheriae: Iron-Mediated Activation of dtxR and Regulation of Diphtheria Toxin Expression<br /> <i>Sadiya Parveen, William R. Bishai, and John R. Murphy<br /> </i><br /> Index</p>

<p>“This textbook comprises a superb collection of scientific knowledge making it a must-read for any graduate student, medical doctor, or investigator studying these gram-positive bacteria and inspiring future imaginations of biological knowledge.”<br /><br />-  William R. Jacobs, Jr., PhD<br />Professor Microbiology & Immunology, Albert Einstein College of Medicine</p> <p> </p>

<p><b>Gram-Positive Pathogens</b> <p>Third Edition <p>Gram-positive bacteria, lacking an outer membrane and related secretory systems and having a thick peptidoglycan, have developed novel approaches to pathogenesis by acquiring (among others) a unique family of surface proteins, toxins, enzymes, and prophages. For the new edition, the editors have enhanced this fully researched compendium of Gram-positive bacterial pathogens by including new data generated using genomic sequencing as well as the latest knowledge on Gram-positive structure and mechanisms of antibiotic resistance and theories on the mechanisms of Gram-positive bacterial pathogenicity. This edition emphasizes streptococci, staphylococci, listeria, and spore-forming pathogens, with chapters written by many of the leading researchers in these areas. The chapters systematically dissect these organisms biologically, genetically, and immunologically, in an attempt to understand the strategies used by these bacteria to cause human disease.

US