Details

<p>Preface</p> <p>Abbreviations</p> <p>1. Haemophagocytic syndrome secondary to anaplastic large cell lymphoma</p> <p>2. Bone marrow AL amyloidosis</p> <p>3. Cup-like blast morphology in acute myeloid leukaemia</p> <p>4. Neutrophil morphology</p> <p>5. Primary myelofibrosis</p> <p>6. Sarcoidosis</p> <p>7. Leishmaniasis</p> <p>8. Gelatinous transformation of the bone marrow</p> <p>9. Acanthocytic red cell disorders</p> <p>10. Large granular lymphocytic leukaemia</p> <p>11. Pure erythroid leukaemia</p> <p>12. Reactive mesothelial cells</p> <p>13. Plasmablastic myeloma</p> <p>14. Septicaemia</p> <p>15. Unstable haemoglobin (haemoglobin Köln) and a myeloproliferative neoplasm</p> <p>16. Sickle cell anaemia in crisis</p> <p>17. Acute myeloid leukaemia with t(8;21)(q22;q22.1)</p> <p>18. Chronic neutrophilic leukaemia</p> <p>19. Essential thrombocythaemia</p> <p>20. Hairy cell leukaemia</p> <p>21. Mantle cell lymphoma in leukaemic phase</p> <p>22. Infantile osteopetrosis</p> <p>23. Reactive eosinophilia</p> <p>24. Stomatocytic red cell disorders</p> <p>25. Reactive lymphocytosis due to viral infection</p> <p>26. Therapy-related acute myeloid leukaemia with eosinophilia</p> <p>27. Red cell fragmentation syndromes</p> <p>28. NK/T-cell lymphoma in leukaemic phase</p> <p>29. Myelodysplastic syndrome with del(5q)</p> <p>30. Classical Hodgkin lymphoma</p> <p>31. Cryoglobulinaemia</p> <p>32. Congenital dyserythropoietic anaemia</p> <p>33. Acute monoblastic leukaemia with t(9;11)(p21.3;q23.3)</p> <p>34. Chronic myeloid leukaemia presenting with myeloid sarcoma and extreme thrombocytosis</p> <p>35. Glucose-6-phosphate dehydrogenase deficiency</p> <p>36. Leukaemic presentation of hepatosplenic gamma-delta T-cell lymphoma</p> <p>37. Myelodysplastic syndromes</p> <p>38. Pelger–Huët anomaly</p> <p>39. Russell bodies in lymphoplasmacytic lymphoma</p> <p>40. T-cell prolymphocytic leukaemia</p> <p>41. Myeloid maturation arrest</p> <p>42. MDS/MPN with ring sideroblasts and thrombocytosis</p> <p>43. Acute myeloid leukaemia with inv(16)(p13.1q22)</p> <p>44. Babesiosis</p> <p>45. Haemoglobin E disorders</p> <p>46. Juvenile myelomonocytic leukaemia</p> <p>47. Non-haemopoietic tumours</p> <p>48. Richter transformation of chronic lymphocytic leukaemia</p> <p>49. Sickle cell-haemoglobin C disease</p> <p>50. T cell/histiocyte-rich B-cell lymphoma</p> <p>51. Miliary tuberculosis</p> <p>52. Pure red cell aplasia</p> <p>53. Lymphoblastic transformation of follicular lymphoma</p> <p>54. Primary hyperparathyroidism</p> <p>55. Gamma heavy chain disease</p> <p>56. Acute promyelocytic leukaemia with t(15;17)(q24.1;q21.2)</p> <p>57. AA amyloidosis</p> <p>58. Acquired sideroblastic anaemia</p> <p>59. Diffuse large B-cell lymphoma</p> <p>60. Hickman line infection</p> <p>61. Monocytes and their precursors</p> <p>62. Paroxysmal cold haemoglobinuria</p> <p>63. Transient abnormal myelopoiesis</p> <p>64. Systemic lupus erythematosus</p> <p>65. Granular blast cells in acute lymphoblastic leukaemia</p> <p>66. Chronic myelomonocytic leukaemia</p> <p>67. Burkitt lymphoma/leukaemia</p> <p>68. Gaucher’s disease</p> <p>69. Myelodysplastic syndrome with haemophagocytosis</p> <p>70. Primary oxalosis</p> <p>71. Acute myeloid leukaemia with inv(3)(q21.3q26.2)</p> <p>72. Autoimmune haemolytic anaemia</p> <p>73. Chronic eosinophilic leukaemia due to FIP1L1-PDGFRA fusion gene</p> <p>74. Leukaemic phase of follicular lymphoma</p> <p>75. Megaloblastic anaemia</p> <p>76. Reactive bone marrow and an abnormal PET scan</p> <p>77. Acute megakaryoblastic leukaemia</p> <p>78. Erythrophagocytosis and haemophagocytosis</p> <p>79. Hyposplenism</p> <p>80. Acquired haemoglobin H disease</p> <p>81. Cystinosis</p> <p>82. Familial platelet disorder with a predisposition to AML</p> <p>83. Nodular lymphocyte predominant Hodgkin lymphoma</p> <p>84. Acute monocytic leukaemia with NPM1 mutation</p> <p>85. Adult T-cell leukaemia/lymphoma</p> <p>86. Hereditary elliptocytosis and pyropoikilocytosis</p> <p>87. Sézary syndrome</p> <p>88. Spherocytic red cell disorders</p> <p>89. Acute myeloid leukaemia and metastatic carcinoma</p> <p>90. Chédiak-Higashi syndrome</p> <p>91. Cortical T-lymphoblastic leukaemia/lymphoma</p> <p>92. Trypanosomiasis</p> <p>93. Acute myeloid leukaemia with myelodysplasia-related changes</p> <p>94. Blastic plasmacytoid dendritic cell neoplasm</p> <p>95. Inherited macrothrombocytopenias</p> <p>96. Persistent polyclonal B-cell lymphocytosis</p> <p>97. Acute myeloid leukaemia with t(6;9)(p23;q34.1)</p> <p>98. B-cell prolymphocytic leukaemia</p> <p>99. Various red cell enzyme disorders</p> <p>100. Sea blue histiocytosis in multiple myeloma</p> <p>101. Enteropathy-associated T-cell lymphoma</p> <p>Answers to multiple choice questions and further reflections on the theme</p> <p>Index</p>

The succinct description of the inset images are well synchronised with clear diction of the detailed clinical commentaries which facilitate integrated learning and reporting - the vital conduit that bridges the bench to the bedside. The whittling down of different diagnoses based on morphological features, along with the warnings about possible pitfalls in many cases, is a true bonus...This book is a 'must have' on the bookshelf of all clinicians and scientists who identify haematology as their calling and vocation.

<p><b>About the Authors</b> <p><b>Mike Leach, MB ChB, FRCP, FRCPath,</b> is Consultant Haematologist and Honorary Senior Lecturer at the Haematology Laboratories and West of Scotland Cancer Centre in Gartnavel General Hospital, Glasgow, UK. <p><b>Barbara J. Bain, MB BS, FRACP, FRCPath,</b> is Professor of Diagnostic Haematology at St Mary’s Hospital Campus, Imperial College London, and Consultant Haematologist at St Mary’s Hospital, London, UK.

<p>Diagnostic haematology requires the assessment of clinical and laboratory data together with a careful morphological assessment of cells in blood, bone marrow and tissue ­fluids. Subsequent investigations including flow cytometry, immunohistochemistry, cytogenetics and molecular studies are guided by the original morphological findings. These targeted investigations help generate a prompt unifying diagnosis. <b><i>Haematology: From the Image to the Diagnosis</i></b> presents a series of cases illustrating how skills in morphology can guide the investigative process. In this book, the authors capture a series of images to illustrate key features to recognize when undertaking a morphological review and show how they can be integrated with supplementary information to reach a final diagnosis. <p>Using a novel format of visual case studies, this text mimics ‘real life’ for the practising diagnostic haematologist – using brief clinical details and initial microscopic morphological triage to formulate a differential diagnosis and a plan for efficient and economical confirmatory investigation to deduce the correct final diagnosis. The carefully selected, high-quality photomicrographs and the clear, succinct descriptions of key features, investigations and results will help haematologists, clinical scientists, haematology trainees and haematopathologists to make accurate diagnoses in their day-to-day work. <p>Covering a wide range of topics, and including paediatric as well as adult cases, <b><i>Haematology: From the Image to the Diagnosis</i></b> is a succinct visual guide which will be welcomed by consultants, trainees and scientists alike.

GB