Details

Principles of Toxicology


Principles of Toxicology

Environmental and Industrial Applications
4. Aufl.

von: Stephen M. Roberts, Robert C. James, Phillip L. Williams

119,99 €

Verlag: Wiley
Format: EPUB
Veröffentl.: 05.04.2022
ISBN/EAN: 9781119635161
Sprache: englisch
Anzahl Seiten: 592

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Beschreibungen

<p><i>Principles of Toxicology</i> concisely and efficiently presents the scientific basis for toxicology as it applies to the workplace and the environment, covering diverse chemical hazards encountered in modern workplaces and natural environments and providing a practical understanding of these hazards for those concerned with protecting the health of humans and ecosystems. The work presents not only theory, but also practical information regarding chemical hazards to give the student and new professional a working knowledge of the practice of toxicology and the ability to solve problems in environmental and industrial settings. <p> Case histories and examples from industrial and environmental exposures to chemicals are included to demonstrate the application of toxicological principles. To allow for seamless reader comprehension and further exploration of covered topics, the work is supplemented with numerous illustrations to clarify and summarize key points, as well as annotated bibliographies. In the 4th edition, all chapters and references have been updated to account for the latest scientific thinking, and new color figures have been added. <p> New topics covered in 4th Edition of <i>Principles of Toxicology</i> include: <ul> <li>Regulatory toxicology, including the key regulatory framework in which much of the field of toxicology operates</li> <li>Alternative methods in toxicology, including cutting-edge approaches to developing new information on the toxicity of drugs and chemicals</li> <li> The dilemma of selecting safe exposure limits, guiding readers through practical considerations and pitfalls in developing and using safe exposure limits </li> <li>Ecological risk assessment, with detailed discussion of methods and considerations when evaluating the effects of contaminants on plants and animals.</li></ul><p>Providing information on the principles of toxicology and the application of those principles to solve problems in environmental and industrial settings, <i>Principles of Toxicology</i> serves as an excellent textbook resource for advanced undergraduate, graduate, and professional students in a range of environmental and health fields. It is also valuable to health professionals who need toxicological information and assistance beyond what is found in an introductory text to general toxicology.
<p>1 General Principles of Toxicology<br /><i>Robert C. James, Stephen M. Roberts, and Phillip L. Williams</i></p> <p>2 Xenobiotic Absorption, Distribution, Metabolism and Excretion<br /><i>Michael R. Franklin</i></p> <p>3 Toxicokinetics<br /><i>Rebecca A. Clewell and Harvey J. Clewell III</i></p> <p>4 Regulatory Toxicology<br /><i>Raymond M. David</i></p> <p>5 Alternative Methods in Toxicity Testing<br /><i>Leona D. Scanlan, XuefeiCao, and Christopher D. Vulpe</i></p> <p>6 ComputationalToxicology<br /><i>Richard S. Judson, David M. Reif, Keith A. Houck, Thomas B. Knudsen, Joshua Harrill, Katie Paul Friedman</i></p> <p>7 Hematotoxicity:Toxic Effects on the Hematopoietic System<br /><i>Lila Ramaiah, Tara Arndt, and Michelle Cora</i></p> <p>8 Hepatotoxicity: Toxic Effects on the Live<br /><i>Robert C. James and Stephen M. Roberts</i></p> <p>9 Nephrotoxicity: Toxic Effects on the Kidney<br /><i>Lawrence H. Lash</i></p> <p>10 Neurotoxicology: Toxic Effects on the Nervous System<br /><i>W. Michael Caudle, Meghan Bucher, Alexandria C. White, and Gary W. Miller</i></p> <p>11 Dermal Toxicology: Toxic Effects on the Skin<br /><i>Sailesh Konda and Howard I Maibach</i></p> <p>12 Pulmonotoxicity: Toxic Effects on the Respiratory System<br /><i>Cuiqing Liu and Qinghua Sun</i></p> <p>13 Immunotoxicity: Toxic Effects on the Immune System<br /><i>Eric S. Sobel and Stephen M. Roberts</i></p> <p>14 Reproductive and Developmental Toxicity: Toxic Effects on the Female and Male Reproductive Tracts and Offspring<br /><i>Shuo Xiao, Krista Symosko, and Charles A. Easley IV</i></p> <p>15 Mutagenesis and Genetic Toxicology<br /><i>Martha M. Moore, Meagan B. Myers and Robert H. Heflich</i></p> <p>16 Chemical Carcinogenesis<br /><i>James E. Klaunig, Luma Melo, and Karen Tilmant</i></p> <p>17 Properties and Effects of Metals<br /><i>David B. Mayfield, Lisa A. Bailey, Joel M. Cohen, and Barbara D. Beck</i></p> <p>18 Pesticides<br />Janice Britt</p> <p>19 Properties and Toxicology of Organic Solvents and Solvent-Like Chemicals<br /><i>Christopher M. Teaf and Michele M. Garber</i></p> <p>20 Nanotoxicology<br /><i>Hongbo Ma and Stephen M. Roberts</i></p> <p>21 Insights into Epidemiology<br /><i>J. Fryzek, C. Frankenfeld, N. Movva, L. Bylsma, and J. Acquavella</i></p> <p>22 Occupational and Environmental Health<br /><i>Laura Breeher, Fredric Gerr, and T. Renėe Anthony</i></p> <p>23 Human Health Risk Assessment<br /><i>Leah D. Stuchal</i></p> <p>24 Ecological Risk Assessment<br /><i>Brett Thomas</i></p> <p>25 The Dilemma of Selecting Safe Exposure Values<br /><i>Robert C. James, Phillip L. Williams,and Stephen M. Roberts</i></p>
<p><b>Stephen M. Roberts, PhD, </B>is Professor and Program Director of the Center for Environmental and Human Toxicology at the University of Florida, Gainesville, FL.</p> <p><b>Robert C. James, PhD,</b> is Senior Science Advisor, ToxStrategies, Boise, ID. <p><b>Phillip L. Williams, PhD, </b>is Dean and Professor Emeritus, College of Public Health, University of Georgia, Athens, GA.
<p><i>Principles of Toxicology</i> concisely and efficiently presents the scientific basis for toxicology as it applies to the workplace and the environment, covering diverse chemical hazards encountered in modern workplaces and natural environments and providing a practical understanding of these hazards for those concerned with protecting the health of humans and ecosystems. The work presents not only theory, but also practical information regarding chemical hazards to give the student and new professional a working knowledge of the practice of toxicology and the ability to solve problems in environmental and industrial settings.</p> <p>Case histories and examples from industrial and environmental exposures to chemicals are included to demonstrate the application of toxicological principles. To allow for seamless reader comprehension and further exploration of covered topics, the work is supplemented with numerous illustrations to clarify and summarize key points as well as annotated bibliographies. In the 4th edition, all chapters and references have been updated to account for the latest scientific thinking, and new color figures have been added. <p>New topics covered in 4th Edition of <i>Principles of Toxicology </i>include: <ul><li>Regulatory toxicology, including the key regulatory framework in which much of the field of toxicology operates</li> <li>Alternative methods in toxicology, including cutting-edge approaches to developing new information on the toxicity of drugs and chemicals</li> <li>The dilemma of selecting safe exposure limits, guiding readers through practical considerations and pitfalls in developing and using safe exposure limits</li> <li>Ecological risk assessment, with detailed discussion of methods and considerations when evaluating the effects of contaminants on plants and animals</li></ul> <p>Providing information on the principles of toxicology and the application of those principles to solve problems in environmental and industrial settings, <i>Principles of Toxicology</i> serves as an excellent textbook resource for advanced undergraduate, graduate, and professional students in a range of environmental and health fields. It is also valuable to health professionals who need toxicological information and assistance beyond what is found in an introductory text to general toxicology.

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