Details

Liver Transplantation


Liver Transplantation

Clinical Assessment and Management
2. Aufl.

von: James Neuberger, James Ferguson, Philip N. Newsome, Michael R. Lucey

134,99 €

Verlag: Wiley-Blackwell
Format: EPUB
Veröffentl.: 25.02.2021
ISBN/EAN: 9781119633990
Sprache: englisch
Anzahl Seiten: 592

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Beschreibungen

<p><b>Explore this practical and step-by-step guide to managing liver transplant patients from leading international clinicians in Hepatology </b></p> <p>The newly revised Second Edition of <i>Liver Transplantation: Clinical Assessment and Management</i> delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Authors are all experts in their field and cover a world-wide perspective. Organized in an accessible, stepwise fashion and packed with text features such as key points, the book covers all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long term care. </p> <p>Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, learn the principles of the procedure and the long term management of the transplant recipient. <i>Liver Transplantation</i> provides the entire hepatology and surgical team the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. </p> <p>Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks. Readers will also enjoy: </p> <ul> <li>A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and abuse of prognostic models </li> <li>An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage a patient with chronic liver disease while on the waiting list </li> <li>A treatment of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list </li> <li>A discussion of care of the liver transplant recipient after the procedure in the short and long term  </li> </ul> <p>Perfect for gastroenterologists, hepatologists, and surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing and following liver transplantation, <i>Liver Transplantation: Clinical Assessment and Management </i>will also earn a place in the libraries of medical students, residents, internal medicine physicians, and GI/Hepatology trainees and all health care professionals providing clinical care to people with liver disease, before, during and after transplantation. </p>
<p>List of Contributors x</p> <p>Foreword to the Second Edition xx</p> <p>Foreword to the First Edition xxi</p> <p>Preface xxii</p> <p>Abbreviations xxiii</p> <p><b>Part 1 When to Refer a Patient for Liver Transplantation </b><b>1</b></p> <p>1 Overview on Organ Donation and Liver Transplantation 3<br /><i>Michael Ronan Lucey</i></p> <p>2 Predicting Outcomes and Use and Abuse of Prognostic Models 11<br /><i>Moira B. Hilscher and Patrick S. Kamath</i></p> <p><b>Part 2 Selection, Assessment, and Management on the List </b><b>19</b></p> <p>3 Assessment of the Potential Transplant Recipient 21<br /><i>Michael L. Volk</i></p> <p>4 Frailty and the Potential Liver Transplant Candidate 27<br /><i>Matthew J. Armstrong and Jennifer C. Lai</i></p> <p>5 Alcohol Use (excluding Alcohol-Related Liver Disease), Tobacco, Marijuana, and Illicit Drugs 33<br /><i>John P. Rice</i></p> <p>6 The Role of the Psychiatric Consultant in the Selection, Assessment, and Management of Liver Transplant Patients 39<br /><i>Robert M. Weinrieb and Arpita Goswami-Banerjee</i></p> <p>7 When Liver Transplant Patients Do Not Adhere to Therapeutic Plans 48<br /><i>Kerry Webb and Rowena Jones</i></p> <p>8 Liver Transplant Assessment for Young People: Addressing the Needs of Young People with Liver Disease 55<br /><i>Marianne Samyn and Jemma Marie Day</i></p> <p>9 Assessment and Management of the Patient with Hepatitis C 64<br /><i>Emma L. Hathorn and David J. Mutimer</i></p> <p>10 Management of Hepatitis B Virus Infection Pre Transplantation 68<br /><i>Bruno Roche and Didier Samuel</i></p> <p>11 Transplantation for the Management of Malignancy 74<br /><i>Adiba I. Azad, Julie K. Heimbach, and Gregory J. Gores</i></p> <p>12 Assessment and Management of the Liver Transplant Candidate with Acute-on-Chronic Liver Failure 82<br /><i>Giovanni Perricone and Rajiv Jalan</i></p> <p>13 Assessment and Management of the Transplant Candidate with Alcohol-Associated Liver Disease 96<br /><i>Stéphanie Faure, Magdalena Meszaros, Lucy Meunier, Hélène Donnadieu-Rigole, and Georges-Philippe Pageaux</i></p> <p>14 Non-alcoholic Fatty Liver Disease as an Indication for Liver Transplantation 104<br /><i>Paul Horn and Philip N. Newsome</i></p> <p>15 Consent 109<br /><i>Christopher J.E. Watson</i></p> <p>16 Prehabilitation and General Management 116<br /><i>Matthew J. Armstrong and Felicity R. Williams</i></p> <p>17 Removal of Patients from the Liver Transplant Waiting List 123<br /><i>John O’Grady</i></p> <p>18 Palliative Care and Liver Transplantation 126<br /><i>Mina Rakoski and Puneeta Tandon</i></p> <p><b>Part 3 Transplantation for Acute Liver Failure </b><b>135</b></p> <p>19 Assessment of the Patient with Acute Liver Failure 137<br /><i>Ashley Barnabas and John O’Grady</i></p> <p>20 Management of the Patient with Fulminant Hepatic Failure Awaiting Liver Transplantation 143<br /><i>Robert J. Fontana</i></p> <p><b>Part 4 Donation and Allocation </b><b>153</b></p> <p>21 Ethical and Legal Aspects of Organ Donation 155<br /><i>Jessica Mellinger</i></p> <p>22 Liver Allocation, Including Principles of Organ Allocation 161<br /><i>Parita Patel and Michael Charlton</i></p> <p>23 Living Donor Liver Transplant in Children 168<br /><i>Adebowale A. Adeyemi, Elizabeth B. Rand, and Kim M. Olthoff</i></p> <p>24 Living Liver Donation in Adults 180<br /><i>Mohamed Rela and Ashwin Rammohan</i></p> <p>25 Deceased Liver Donors: Standard and Expanded Criteria 190<br /><i>Shareef Syed and Sandy Feng</i></p> <p>26 Donor-Transmitted Disease 203<br /><i>James Neuberger</i></p> <p>27 Liver Donation and Preservation 209<br /><i>Navneet Tiwari and Hynek Mergental</i></p> <p>28 Liver Retrieval and Preservation 223<br /><i>Carlo D.L. Ceresa, Brian R. Davidson, Peter J. Friend, and Rutger J. Ploeg</i></p> <p>29 Alternatives to Whole Graft Liver Transplantation 236<br /><i>Paolo Muiesan, Alessandro Parente, and Hector Vilca-Melendez</i></p> <p>30 Surgical Aspects of Deceased Donor Transplantation 252<br /><i>Amit Nair, K.V. Narayanan Menon, Cristiano Quintini, and Charles Miller</i></p> <p><b>Part 5 Care of the Liver Transplant Recipient </b><b>265</b></p> <p>31 Outcomes after Liver Transplantation 267<br /><i>James Neuberger</i></p> <p>32 Outpatient Follow-Up of Liver Transplant Recipients 276<br /><i>Amardeep Khanna and James Ferguson</i></p> <p>33 Medication Adherence 285<br /><i>Maureen Whitsett and Josh Levitsky</i></p> <p>34 Transitional Care 299<br /><i>Fiona Thompson</i></p> <p>35 Managing the Liver Transplant Recipient with Abnormal Liver Blood Tests 303<br /><i>Joanna A. Leithead</i></p> <p>36 The Immune System in Liver Transplantation: Rejection versus Tolerance 317<br /><i>Palak J. Trivedi and Nick D. Jones</i></p> <p>37 Immunosuppressive Medications: Liver Transplantation 334<br /><i>Tim Mitchell and Gerry MacQuillan</i></p> <p>38 Immunosuppression in Liver Transplantation 344<br /><i>Nicholas Lim and John R. Lake</i></p> <p>39 Patterns of Liver Allograft Rejection 353<br /><i>Geoffrey W. McCaughan, Ken Liu, Avik Majumdar, Patrick Bertolino, David G. Bowen, and Simone I. Strasser</i></p> <p>40 De Novo Autoimmune Hepatitis 360<br /><i>James Neuberger</i></p> <p>41 Managing Rejection 364<br /><i>Neil Halliday and Douglas Thorburn</i></p> <p>42 Withdrawal of Immunosuppression after Liver Transplantation 386<br /><i>Luca Toti, Tommaso Maria Manzia, Francesca Blasi, and Giuseppe Tisone</i></p> <p>43 Liver Transplant Pathology 393<br /><i>Owen L. Cain and Stefan G. Hübscher</i></p> <p>44 Care of the Liver Transplant Recipient: Management of Renal Function 403<br /><i>Andres F. Carrion and Paul Martin</i></p> <p>45 Managing Cardiovascular Risk in the Liver Transplant Recipient 409<br /><i>Manhal Izzy and Kymberly D. Watt</i></p> <p>46 Bone Disease in Liver Transplantation 418<br /><i>John Ayuk</i></p> <p>47 Diagnosis and Management of Recurrent Autoimmune Liver Disease 424<br /><i>Fernanda Q. Onofrio, Nazia Selzner, and Gideon M. Hirschfield</i></p> <p>48 NAFLD and NASH in the Patient after Liver Transplantation 438<br /><i>Paul Horn and Philip N. Newsome</i></p> <p>49 Recurrent Metabolic Diseases 445<br /><i>James Neuberger</i></p> <p>50 Treatment of Hepatitis C in the Transplant Setting 449<br /><i>Jeffrey Kahn and Norah A. Terrault</i></p> <p>51 Management of Hepatitis B Virus Infection Post Transplantation 458<br /><i>Bruno Roche and Didier Samuel</i></p> <p>52 Antimicrobial Prophylaxis Following Liver Transplantation 469<br /><i>Michael J. Williams and Peter C. Hayes</i></p> <p>53 Cytomegalovirus and the Liver Transplant Recipient 475<br /><i>James Ferguson</i></p> <p>54 Post-Liver Transplant Infections 481<br /><i>Miruna David and Ahmed Elsharkawy</i></p> <p>55 De Novo Malignancies after Liver Transplantation 493<br /><i>Simone I. Strasser, Ken Liu, Avik Majumdar, and Geoffrey W. McCaughan</i></p> <p>56 Post-Transplant Lymphoproliferative Disorders 500<br /><i>Jose Ignacio Herrero</i></p> <p>57 Quality of Life and Employment after Liver Transplantation 507<br /><i>Santiago Tome, Esteban Otero, and Michael Ronan Lucey</i></p> <p>58 Sexual Function, Fertility, and Pregnancy in Liver Disease and after Liver Transplantation 514<br /><i>Patrizia Burra, Salvatore Stefano Sciarrone, and Patrizio Bo</i></p> <p>59 Common Drug Interactions 519<br /><i>Amanda Smith</i></p> <p>60 Immunization and Liver Transplantation 525<br /><i>Jessica Hause and Erin Spengler</i></p> <p>Postscript 529<br /><i>James Neuberger</i></p> <p>Index 531</p>
<p><b>JAMES NEUBERGER, DM, FRCP</b> is Consultant Physician in the Liver Unit, Birmingham, UK. A previous President of the British Association for the Study of the Liver, he has over 35 years of liver transplantation and disease experience and has edited five books on liver disease and liver transplantation and published extensively in liver disease and transplantation.</p> <p><b>JAMES FERGUSON, MD, FRCPE</b> is Consultant Hepatologist at the Queen Elizabeth Hospital in Birmingham, UK. He has extensive experience in managing patients with liver disease and in liver transplantation. <p><b>PHILIP N. NEWSOME, PHD, FRCPE</b> is Professor of Experimental Hepatology and Honorary Consultant Hepatologist, Director of Research and Knowledge Transfer for the College of Medical & Dental Sciences and Director of the Centre for Liver and Gastrointestinal Research in the University of Birmingham, UK. Currently Secretary General of the European Association for the Study of the Liver, he continues to research in all aspects of liver disease and stem cell therapy. <p><b>MICHAEL RONAN LUCEY, MD, FRCPI</b> is Chief of the Division of Gastroenterology and Hepatology at the University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. A past President of the American Society of Transplantation, he continues to publish widely in the field of liver disease and liver transplantation.
<p><b>A COMPLETE GUIDE TO THE MANAGEMENT OF PATIENTS AT EVERY STAGE OF LIVER TRANSPLANTATION</b> <p>The newly revised Second Edition of <i>Liver Transplantation: Clinical Assessment and Management</i> delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Each author is a leader in their field and together they cover a world-wide perspective, addressing all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long-term care. <p>Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, procedural principles and the long-term management of the transplant recipient. <i>Liver Transplantation</i> provides the entire hepatology and surgical team with the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. <p>Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks, offering: <li><bl>A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and potential misuse of prognostic models</bl></li> <li><bl>An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage patients with chronic liver disease</bl></li> <li><bl>An examination of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list</bl></li> <li><bl>A discussion of care of the liver transplant recipient after the procedure in the short and long term</bl></li> <p>Designed for gastroenterologists, hepatologists, surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing or recovering from transplantation, <i>Liver Transplantation: Clinical Assessment and Management</i> is a practical and authoritative guide to all aspects of this complex and vital procedure.

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