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<p>Preface vii</p> <p>List of abbreviations ix</p> <p><b>Part 1: Foundations of Endocrinology 1</b></p> <p>1 Overview of endocrinology 3</p> <p>2 Basic cell biology and hormone synthesis 12</p> <p>3 Molecular basis of hormone action 22</p> <p>4 Investigations in endocrinology and diabetes 39</p> <p><b>Part 2: Endocrinology – Biology to Clinical Practice 51</b></p> <p>5 The hypothalamus and pituitary gland 53</p> <p>6 The adrenal gland 80</p> <p>7 Reproductive endocrinology 103</p> <p>8 The thyroid gland 134</p> <p>9 Calcium and metabolic bone disorders 155</p> <p>10 Pancreatic and gastrointestinal endocrinology and endocrine neoplasia 175</p> <p><b>Part 3: Diabetes and Obesity 193</b></p> <p>11 Overview of diabetes 195</p> <p>12 Type 1 diabetes 213</p> <p>13 Type 2 diabetes 239</p> <p>14 Complications of diabetes 265</p> <p>15 Obesity 293</p> <p>Index 311</p>

<p><b>Richard Holt</b> is Professor in Diabetes and Endocrinology at the University of Southampton, UK, and Honorary Consultant in Diabetes at University Hospital Southampton NHS Foundation Trust.  </p> <p> </p> <p><b>Neil Hanley</b> is Professor of Medicine at the University of Manchester, UK, and Honorary Consultant in Endocrinology at the Manchester University NHS Foundation Trust. </p>

<p>The <i>Essentials</i> are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wiley.com for further details.</p><p><i>Essential Endocrinology and Diabetes</i> provides the accurate and up-to-date knowledge required for treating all areas of endocrinology and diabetes, covering the latest research, clinical guidelines, investigational methods, and therapies. This classic text explains the vital aspects of endocrine physiology in a succinct and easy-to-use format, with full-colour illustrations, clinical images, and case studies to assist readers in applying theory to practice.</p><p>The text covers the principles of endocrinology, clinical endocrinology, and clinical diabetes and obesity, and has been revised throughout to present the most recent developments in the field. The seventh edition includes new and updated material on the latest molecular techniques, approaches to clinical investigation and diagnostics, next generation sequencing technology, and positron emission tomography (PET). The treatment of type 1 diabetes and type 2 diabetes has been updated with clinical algorithms and reflects significant advances such as incretin-based therapies, SGLT2 inhibitors, the development of better insulins, and technologies that support self-management.</p> <li><bl>Provides students and practitioners with comprehensive and authoritative information on all major aspects of endocrine physiology</bl></li><li><bl>Covers diagnosis, management, and complications of clinical disorders such as endocrine neoplasia, and type 1 diabetes and type 2 diabetes</bl></li><li><bl>Explains the core principle of feedback regulation, which is vital for the correct interpretation of many clinical tests</bl></li><li><bl>Features case histories, learning objectives, ‘recap’ links to chapter content, cross-referencing guides, key information boxes, and chapter summaries</bl></li> <p><i>Essential Endocrinology and Diabetes, Seventh Edition</i> is the ideal textbook for medical and biomedical students, junior doctors, and clinicians looking to refresh their knowledge of endocrine science.</p> <p>For more information on the complete range of Wiley medical student and junior doctor publishing, please visit: <b>www.wiley.com</b></p><p>To receive automatic updates on Wiley books and journals, join our email list. Sign up today at <b>www.wiley.com/email</b></p><p><b>All content reviewed by students for students</b></p><p>Wiley Medical Education books are designed exactly for their intended audience. All of our books are developed in collaboration with students. This means that our books are always published with you, the student, in mind.</p><p>If you would like to be one of our student reviewers, go to <b>www.reviewmedicalbooks.com</b> to find out more.</p><p>This title is also available as an e-book. For more details, please see <b>www.wiley.com/buy/9781118763964</b></p>

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